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The Neurologic Side Effects of Chemotherapeutic Agents

Dropcho, Edward J. MD

doi: 10.1212/01.CON.0000394676.67372.87
Review Articles

Neurologic dysfunction is a common side effect of many chemotherapy drugs. For several agents neurotoxicity is common, severe, and can be dose limiting. As the list of newer chemotherapy agents and systemic targeted therapies grows, so does the number and variety of potential neurotoxicities. This article reviews the clinical features of chemotherapy-induced syndromes involving the central and peripheral nervous systems.

Address correspondence to Dr Edward Dropcho, Indiana University Medical Center, 541 Clinical Drive, Department of Neurology, Cl 292, Indianapolis, IN46202, edropcho@iupui.edu.

Relationship Disclosure: Dr Dropcho has received personal compensation for speaking engagements with Merck & Co., Inc., and in an editorial capacity from Medlink Neurology.

Unlabeled Use of Products/Investigational Use Disclosure: Dr Dropcho has nothing to disclose.

© 2011 American Academy of Neurology