Opioids have demonstrated efficacy in relieving neuropathic pain. Familiarity with the pharmacology and adverse effect profile of this class of medication is essential for its safe and optimal use, as is knowledge of the regulatory requirements related to opioid prescribing. Opioids are versatile and can be effective as part of a rational multidrug therapeutic approach. As such, they are an integral part of the multimodal and multidisciplinary treatment of neuropathic pain.
Relationship Disclosure: Dr Backonja has received personal compensation for activities with Abbott Laboratories, Inc., Eli Lilly and Company, Endo Pharmaceuticals, Grünenthal, Johnson & Johnson, Merck & Co., Inc., NeurogesX, and Valeant Pharmaceuticals, Inc. Dr Backonja has received research support from Eli Lilly and Company, Johnson & Johnson, NeurogesX, and Valeant Pharmaceuticals, Inc.
Unlabeled Use of Products/Investigational Use Disclosure: Dr Backonja has nothing to disclose.