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HEREDITARY MYELOPATHIES

Fink, John K.

doi: 10.1212/01.CON.0000324124.55065.09
Article

Hereditary myelopathies are a diverse group of disorders in which major aspects of the clinical syndrome involve spinal cord structures. Hereditary myelopathic syndromes can be recognized as four clinical paradigms: (1) spinocerebellar ataxia, (2) motor neuron disorder, (3) leukodystrophy, and (4) distal motor-sensory axonopathy. This review illustrates these hereditary myelopathy paradigms with clinical examples with an emphasis on clinical recognition and differential diagnosis.

Relationship Disclosure: Dr Fink has received personal compensation from Athena Diagnostics, Inc. Dr Fink has received royalty payments for atlastin and NIPA1 patents.

Unlabeled Use of Products/Investigational Use Disclosure: Dr Fink has nothing to disclose.

© 2008 American Academy of Neurology
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