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DISEASE-MODIFYING THERAPIES

Mehta, Lahar R.; Goodman, Andrew D.

doi: 10.1212/01.CON.0000293644.43858.54
Article

The introduction of disease-modifying therapies has revolutionized the care of patients with multiple sclerosis (MS). Currently six agents have been specifically approved for use in MS. These include three formulations of interferon beta, glatiramer acetate, mitoxantrone, and natalizumab. Evidence supporting their use includes demonstrable impact on relapse rate, MRI measures of lesion activity and accumulation, as well as (in some cases) a favorable impact on disability progression.

© 2007 American Academy of Neurology
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