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PATHOPHYSIOLOGY OF MIGRAINE

Goadsby, Peter J.

CONTINUUM: Lifelong Learning in Neurology: December 2006 - Volume 12 - Issue 6, Headache - p 52-66
doi: 10.1212/01.CON.0000290523.47203.c3
Article

Primary headache is a common problem in neurology. The main disabling form of primary headache presenting to neurologists is migraine, either episodic or chronic. Migraine is an inherited disorder of the brain that involves dysfunction of subcortical structures that modulate sensory input. Its therapy involves reducing afferent traffic or stabilizing these abnormal pathways. Understanding the pathophysiology of migraine is integral to providing explanations to patients and good management strategies.

© 2006 American Academy of Neurology
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