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Compulsive Singing Associated With a Dopamine Agonist in Parkinson Disease

Kataoka, Hiroshi MD, PhD; Ueno, Satoshi MD, PhD

Cognitive & Behavioral Neurology: June 2010 - Volume 23 - Issue 2 - pp 140-141
doi: 10.1097/WNN.0b013e3181c12af2
Case Reports

Objective: To describe a patient with Parkinson disease in whom compulsive singing developed without other types of pathologic behavior after starting treatment with pergolide.

Material: An 82-year-old woman with Parkinson disease was given pergolide (250 μg/d), without modifying the doses of other medications.

Results: She started to hum the same melody and often sang songs repeatedly. Pergolide was discontinued, and the episodes of repetitive humming and singing were markedly decreased.

Conclusions: Our observations suggest that a dopamine agonist may contribute to compulsive singing in Parkinson disease.

Department of Neurology, Nara Medical University, Kashihara, Nara, Japan

Reprints: Hiroshi Kataoka, MD, PhD, Department of Neurology, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8522, Japan (e-mail:

Received for publication March 19, 2009

accepted September 13, 2009

© 2010 Lippincott Williams & Wilkins, Inc.