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Current Opinion in Organ Transplantation:
doi: 10.1097/MOT.0b013e32835daf68
CURRENT WORLD LITERATURE: Bibliography

Current World Literature

Free Access

This bibliography is compiled by clinicians from the relevant journals scanned by this publication. It is based on the literature regularly pulled into our database from OvidSP (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

▪ Papers considered by the reviewers to be of special interest

▪▪ Papers considered by the reviewers to be of outstanding interest

The number in square brackets following a selected paper, e.g. [7], refers to its number in the annotated references of the corresponding review.

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Mechanisms of rejection
Non-invasive biomarkers to guide management following renal transplantation: the need for a multiplatform approach

Review: (pp. 1–5)

Agorogiannis EI, Regateiro FS, Howie D, Waldmann H, et al. Th17 Cells Induce a Distinct Graft Rejection Response That Does Not Require IL-17A. Am J Transplant 2012; 12:835–845. View Full Text | PubMed | CrossRef

Alachkar N. Serum and urinary biomarkers in acute kidney transplant rejection. Nephrol Ther 2012; 8:13–19. PubMed

Andreev VP, Tryphonopoulos P, Blomberg BB, Tsinoremas N, et al. Peripheral Blood Gene Expression Analysis in Intestinal Transplantation: A Feasibility Study for Detecting Novel Candidate Biomarkers of Graft Rejection. Transplantation 2011; 92:1385–1391. View Full Text | PubMed | CrossRef

Asaoka T, Sotolongo B, Island ER, Tryphonopoulos P, et al. MicroRNA Signature of Intestinal Acute Cellular Rejection in Formalin-Fixed Paraffin-Embedded Mucosal Biopsies. Am J Transplant 2012; 12:458–468. View Full Text | PubMed | CrossRef

Ashokkumar C, Ningappa M, Ranganathan S, Higgs BW, et al. Increased Expression of Peripheral Blood Leukocyte Genes Implicate CD14(+) Tissue Macrophages in Cellular Intestine Allograft Rejection. Am J Pathol 2011; 179:1929–1938. PubMed | CrossRef

Badell IR, Thompson PW, Turner AP, Russell MC, et al. Nondepleting Anti-CD40-Based Therapy Prolongs Allograft Survival in Nonhuman Primates. Am J Transplant 2012; 12:126–135.

Bestard O, Cunetti L, Cruzado JM, Lucia M, et al. Intragraft Regulatory T Cells in Protocol Biopsies Retain Foxp3 Demethylation and Are Protective Biomarkers for Kidney Graft Outcome. Am J Transplant 2011; 11:2162–2172. View Full Text | PubMed | CrossRef

Camirand G, Li Q, Demetris AJ, Watkins SC, et al. Multiphoton Intravital Microscopy of the Transplanted Mouse Kidney. Am J Transplant 2011; 11:2067–2074. View Full Text | PubMed | CrossRef

Chen G, Mi J, Xiao MZ, Fu YR. PDIA3 mRNA expression and IL-2, IL-4, IL-6, and CRP levels of acute kidney allograft rejection in rat. Mol Biol Rep 2012; 39:5233–5238. PubMed | CrossRef

Chen JH, Wen H, Liu J, Yu C, et al. Metabonomics study of the acute graft rejection in rat renal transplantation using reversed-phase liquid chromatography and hydrophilic interaction chromatography coupled with mass spectrometry. Mol Biosyst 2012; 8:871–878. PubMed

Cohen D, Colvin RB, Daha MR, Drachenberg CB, et al. Pros and cons for C4d as a biomarker. Kidney Int 2012; 81:628–639. PubMed | CrossRef

Conway J, Manlhiot C, Allain-Rooney T, McCrindle BW, et al. Development of Donor-Specific Isohemagglutinins Following Pediatric ABO-Incompatible Heart Transplantation. Am J Transplant 2012; 12:888–895. View Full Text | PubMed | CrossRef

Cravedi P, Heeger PS. Immunologic monitoring in transplantation revisited. Curr Opin Organ Transpl 2012; 17:26–32. View Full Text | PubMed | CrossRef

Cui YX, Huang QH, Auman JT, Knight B, et al. Genomic-Derived Markers for Early Detection of Calcineurin Inhibitor Immunosuppressant-Mediated Nephrotoxicity. Toxicol Sci 2011; 124:23–34.

Dharnidharka VR. Less invasive biomarkers of acute rejection: Reaching the elusive clinic. Pediatr Transplant 2012; 16:308–309. View Full Text | PubMed | CrossRef

Dyer AK, Barnes AP, Fixler DE, Shah TK, et al. Use of a highly sensitive assay for cardiac troponin T and N-terminal pro-brain natriuretic peptide to diagnose acute rejection in pediatric cardiac transplant recipients. Am Heart J 2012; 163:595–600. View Full Text | PubMed | CrossRef

Farid WRR, Pan QW, van der Meer AJP, de Ruiter PE, et al. Hepatocyte-derived microRNAs as serum biomarkers of hepatic injury and rejection after liver transplantation. Liver Transplant 2012; 18:290–297. PubMed | CrossRef

Fleissner F, Goerzig Y, Haverich A, Thum T. Microvesicles as Novel Biomarkers and Therapeutic Targets in Transplantation Medicine. Am J Transplant 2012; 12:289–297. View Full Text | PubMed | CrossRef

Garcia-Roca P, Vargas YA, Fuentes Y, Hernandez AM, et al. Serum soluble interleukin 2 receptor (sIL-2R) as a marker of acute rejection in renal transplant children. Pediatr Transplant 2012; 16:274–279. View Full Text | PubMed | CrossRef

Gong W, Whitcher GH, Townamchai N, Xiao X, et al. Biomarkers for Monitoring Therapeutic Side Effects or Various Supratherapeutic Confounders after Kidney Transplantation. Transplant Proc 2012; 44:1265–1269. PubMed | CrossRef

He B, Zhang YT, Yuan XG, Sun JS, et al. Protective effects of Radix Codonopsis on ischemia-reperfusion injury in rats after kidney transplantation. Pediatr Surg Int 2011; 27:1203–1212. PubMed | CrossRef

Hirt-Minkowski P, Amico P, Ho J, Gao A, et al. Detection of Clinical and Subclinical Tubulo-Interstitial Inflammation by the Urinary CXCL10 Chemokine in a Real-Life Setting. Am J Transplant 2012; 12:1811–1823. PubMed | CrossRef

Ho JL, Rush DN, Karpinski M, Storsley L, et al. Validation of Urinary CXCL10 As a Marker of Borderline, Subclinical, and Clinical Tubulitis. Transplantation 2011; 92:878–882. View Full Text | PubMed | CrossRef

Jimenez-Sousa MA, Fernandez-Rodriguez A, Heredia M, Tamayo E, et al. Genetic polymorphisms located in TGFB1, AGTR1, and VEGFA genes are associated to chronic renal allograft dysfunction. Cytokine 2012; 58:321–326. View Full Text | PubMed | CrossRef

Johnston O, Cassidy H, O'Connell S, O'Riordan A, et al. Identification of beta 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods. Proteom Clin Appl 2011; 5:422–431.

Kienzl-Wagner K, Pratschke J, Brandacher G. Proteomics-A Blessing or a Curse? Application of Proteomics Technology to Transplant Medicine. Transplantation 2011; 92:499–509.

Kim C, Aono S, Marubashi S, Wada H, et al. Significance of Alanine Aminopeptidase N (APN) in Bile in the Diagnosis of Acute Cellular Rejection After Liver Transplantation. J Surg Res 2012; 175:138–148. PubMed | CrossRef

Konvalinka A, Scholey JW, Diamandis EP. Searching for New Biomarkers of Renal Diseases through Proteomics. Clin Chem 2012; 58:353–365. PubMed | CrossRef

Kosanam H, Sato M, Batruch I, Smith C, et al. Differential proteomic analysis of bronchoalveolar lavage fluid from lung transplant patients with and without chronic graft dysfunction. Clin Biochem 2012; 45:223–230. PubMed | CrossRef

Kusaka M, Iwamatsu F, Kuroyanagi Y, Nakaya M, et al. Serum Neutrophil Gelatinase Associated Lipocalin During the Early Postoperative Period Predicts the Recovery of Graft Function After Kidney Transplantation From Donors After Cardiac Death. J Urol 2012; 187:2261–2267. View Full Text | PubMed | CrossRef

Labarrere CA, Jaeger BR. Biomarkers of heart transplant rejection: the good, the bad, and the ugly!. Transl Res 2012; 159:238–251.

Lee JS, Song JW, Wolters PJ, Elicker BM, et al. Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis. Eur Resp J 2012; 39:352–358. PubMed | CrossRef

Lehnhardt A, Dunst F, van Husen M, Loos S, et al. Elevated serum levels of B-cell activating factor in pediatric renal transplant patients. Pediatr Nephrol 2012; 27:1389–1395. PubMed | CrossRef

▪. Li L, Khatri P, Sigdel TK, et al. A Peripheral Blood Diagnostic Test for Acute Rejection in Renal Transplantation. Am J Transplant 2012; 12:2710–2718. [05]

Londono MC, Danger R, Giral M, Soulillou JP, et al. A Need for Biomarkers of Operational Tolerance in Liver and Kidney Transplantation. Am J Transplant 2012; 12:1370–1377. View Full Text | PubMed | CrossRef

Lorenzen JM, Volkmann I, Fiedler J, Schmidt M, et al. Urinary miR-210 as a Mediator of Acute T-Cell Mediated Rejection in Renal Allograft Recipients. Am J Transplant 2011; 11:2221–2227. View Full Text | PubMed | CrossRef

Lozano JJ, Pallier A, Martinez-Llordella M, Danger R, et al. Comparison of Transcriptional and Blood Cell-Phenotypic Markers Between Operationally Tolerant Liver and Kidney Recipients. Am J Transplant 2011; 11:1916–1926. View Full Text | PubMed | CrossRef

Minisini R, Giarda P, Grossi G, Bitetto D, et al. Early activation of interferon-stimulated genes in human liver allografts: relationship with acute rejection and histological outcome. J Gastroenterol 2011; 46:1307–1315. PubMed | CrossRef

Mullen W, Delles C, Mischak H. Urinary proteomics in the assessment of chronic kidney disease. Curr Opin Nephrol Hypertens 2011; 20:654–661. View Full Text | PubMed | CrossRef

Neujahr DC, Perez SD, Mohammed A, Ulukpo O, et al. Cumulative Exposure to Gamma Interferon-Dependent Chemokines CXCL9 and CXCL10 Correlates with Worse Outcome After Lung Transplant. Am J Transplant 2012; 12:438–446.

▪▪. Newell KA, Asare A, Kirk AD, et al. Identification of a B cell signature associated with renal transplant tolerance in humans. J Clin Invest 2010; 120:1836–1847. [38]

Pascual-Figal DA, Garrido IP, Blanco R, Minguela A, et al. Soluble ST2 Is a Marker for Acute Cardiac Allograft Rejection. Ann Thorac Surg 2011; 92:2118–2124. View Full Text | PubMed | CrossRef

▪. Pham MX, Teuteberg JJ, Kfoury AG, et al. Gene-expression profiling for rejection surveillance after cardiac transplantation. N Engl J Med 2010; 362:1890–1900. [10]

Pisitkun T, Gandolfo MT, Das S, Knepper MA, et al. Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation. Proteom Clin Appl 2012; 6:268–278.

Reilly C, Cervenka T, Hertz MI, Becker T, et al. Human neutrophil peptide in lung chronic allograft dysfunction. Biomarkers 2011; 16:663–669. PubMed | CrossRef

Rodriguez-Peralvarez M, Germani G, Tsochatzis E, Rolando N, et al. Predicting severity and clinical course of acute rejection after liver transplantation using blood eosinophil count. Transpl Int 2012; 25:555–563. View Full Text | PubMed | CrossRef

▪▪. Sagoo P, Perucha E, Sawitzki B, et al. Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans. J Clin Invest 2010; 120:1848–1861. [39]

Santolaya JL, Galan I, Di Stefano V, Jasani S, et al. Candidate Biomarkers for Acute Rejection of Pregnancy After in-utero Cell-Based Therapy in Pre-Immune Embryos via Ultrasound-Guided Celocentesis. Am J Reprod Immunol 2012; 68:181–184. View Full Text | PubMed | CrossRef

Shaw SM, Critchley WR, Puchalka CM, Williams SG, et al. Brain natriuretic peptide induces CD8+T cell death via a caspase 3 associated pathway - Implications following heart transplantation. Transpl Immunol 2012; 26:119–122. PubMed | CrossRef

Sindhi R, Ashokkumar C, Higgs BW, Gilbert PB, et al. Allospecific CD154+T-cytotoxic memory cells as potential surrogate for rejection risk in pediatric intestine transplantation. Pediatr Transplant 2012; 16:83–91. View Full Text | PubMed | CrossRef

Soulez M, Pilon EA, Dieude M, Cardinal H, et al. The Perlecan Fragment LG3 Is a Novel Regulator of Obliterative Remodeling Associated With Allograft Vascular Rejection. CircRes 2012; 110:94–104. View Full Text | PubMed | CrossRef

Spivey TL, Uccellini L, Ascierto ML, Zoppoli G, et al. Gene expression profiling in acute allograft rejection: challenging the immunologic constant of rejection hypothesis - art. no. 174. J Transl Med 2011; 9:12.

Vieyra M, Leisman S, Raedler H, Kwan WH, et al. Complement Regulates CD4 T-Cell Help to CD8 T Cells Required for Murine Allograft Rejection. Am J Pathol 2011; 179:766–774. PubMed | CrossRef

Viglietti D, Peraldi MN. Cytopenias following kidney transplantation. Nephrol Ther 2011; 7:474–478. PubMed

Wang MM, Jin Q, Tu HY, Mao YY, et al. Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis. Int Urol Nephrol 2011; 43:1009–1017. PubMed | CrossRef

Wei L, Wang M, Qu X, Mah A, et al. Differential Expression of MicroRNAs During Allograft Rejection. Am J Transplant 2012; 12:1113–1123. View Full Text | PubMed | CrossRef

Weigt SS, Derhovanessian A, Liao E, Hu S, et al. CXCR3 Chemokine Ligands During Respiratory Viral Infections Predict Lung Allograft Dysfunction. Am J Transplant 2012; 12:477–484. View Full Text | PubMed | CrossRef

Xie L, Ichimaru N, Morita M, Chen JJ, et al. Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance. Liver Transplant 2012; 18:444–454.

Xu XG, Huang HY, Cai M, Qian YY, et al. Serum hematopoietic growth factors as diagnostic and prognostic markers of acute renal allograft rejection: A potential role for serum stem cell factor. Cytokine 2011; 56:779–785. View Full Text | PubMed | CrossRef

Yaghobi R, Karimi MH, Namayandeh M, Geramizadeh B, et al. The Association of Polymorphisms in Cytokine Genes with Acute Rejection and the Pathogenesis of Hepatitis B and C in Liver Transplant Recipients. Labmedicine 2012; 43:181–188.

Ziegler ME, Chen TC, Le Blanc JF, Wei XL, et al. Apolipoprotein A1 and C-Terminal Fragment of alpha-1 Antichymotrypsin Are Candidate Plasma Biomarkers Associated With Acute Renal Allograft Rejection. Transplantation 2011; 92:388–395. View Full Text | PubMed | CrossRef

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New perspectives in transplantation through intravital microscopy imaging

Review: (pp. 6–12)

▪. Abdulreda MH, Faleo G, Molano RD, et al. High-resolution, noninvasive longitudinal live imaging of immune responses. Proc Natl Acad Sci 2011; 108:1–13. [22]

Arifin DR, Bulte JWM. Imaging of pancreatic islet cells. Diabetes-Metab Res Rev 2011; 27:761–766. PubMed | CrossRef

Aygen M, Amirmokri P, Berk F, Nguyen N, et al. A preliminary report on Tc-99m-fanolesomab imaging of renal allograft. Nucl Med Commun 2011; 32:925–928. View Full Text | PubMed | CrossRef

Bader FM, Islam N, Mehta NA, Worthen N, et al. Noninvasive Diagnosis of Cardiac Allograft Rejection Using Echocardiography Indices of Systolic and Diastolic Function. Transplant Proc 2011; 43:3877–3881. PubMed | CrossRef

Barnett BP, Ruiz-Cabello J, Hota P, Ouwerkerk R, et al. Use of perfluorocarbon nanoparticles for non-invasive multimodal cell tracking of human pancreatic islets. Contrast Media Mol Imaging 2011; 6:251–259.

Borot S, Crowe LA, Toso C, Vallee JP, et al. Noninvasive Imaging Techniques in Islet Transplantation. Curr Diabetes Rep 2011; 11:375–383. PubMed | CrossRef

▪. Camirand G, Li Q, Demetris AJ, et al. Multiphoton intravital microscopy of the transplanted mouse kidney. Am J Transplant 2011; 11:2067–2074. [04]

▪▪. Celli S, Albert ML, Bousso P. Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy. Nat Med 2011; 17:744–749. [23]

Eriksson O, Alavi A. Imaging the islet graft by positron emission tomography. Eur J Nucl Med Mol Imaging 2012; 39:533–542. View Full Text | PubMed | CrossRef

Fleissner F, Goerzig Y, Haverich A, Thum T. Microvesicles as Novel Biomarkers and Therapeutic Targets in Transplantation Medicine. Am J Transplant 2012; 12:289–297. View Full Text | PubMed | CrossRef

▪▪. Germain RN, Robey EA, Cahalan MD. A decade of imaging cellular motility and interaction dynamics in the immune system. Science 2012; 336:1676–1681. [32]

Goland S, Siegel RJ, Burton K, De Robertis MA, et al. Changes in left and right ventricular function of donor hearts during the first year after heart transplantation. Heart 2011; 97:1681–1686. View Full Text | PubMed | CrossRef

Jeong WK, Kim KW, Lee SJ, Shin YM, et al. Hepatofugal Portal Venous Flow on Doppler Sonography After Liver Transplantation Analysis of presumed causes based on radiologic and pathologic features. J Ultrasound Med 2012; 31:1069–1079. PubMed

Kahraman S, Dirice E, Hapil FZ, Ertosun MG, et al. Tracing of islet graft survival by way of in vivo fluorescence imaging. Diabetes-Metab Res Rev 2011; 27:575–583. PubMed | CrossRef

Kim JH, Jin SM, Oh SH, Lee S, et al. Counting Small Hypointense Spots Confounds the Quantification of Functional Islet Mass Based on Islet MRI. Am J Transplant 2012; 12:1303–1312. View Full Text | PubMed | CrossRef

Kriz J, Jirak D, Berkova Z, Herynek V, et al. Detection of pancreatic islet allograft impairment in advance of functional failure using magnetic resonance imaging. Transpl Int 2012; 25:250–260. View Full Text | PubMed | CrossRef

Lee VS, Miller FH, Omary RA, Wang Y, et al. Magnetic Resonance Elastography and Biomarkers to Assess Fibrosis From Recurrent Hepatitis C in Liver Transplant Recipients. Transplantation 2011; 92:581–586. View Full Text | PubMed | CrossRef

▪▪. Li W, Nava RG, Bribriesco AC, et al. Intravital 2-photon imaging of leukocyte trafficking in beating heart. J Clin Invest 2012; 122:2499–2508. [20]

Lin YH, Yeh YC, Tzeng CR, Shang WJ, et al. Evaluating the effects of immunosuppression by in-vivo bioluminescence imaging after allotransplantation of ovarian grafts. Reprod Biomed Online 2011; 22:220–227. PubMed | CrossRef

Michaely HJ, Metzger L, Haneder S, Hansmann J, et al. Renal BOLD-MRI does not reflect renal function in chronic kidney disease. Kidney Int 2012; 81:684–689. PubMed | CrossRef

▪▪. Moreau HD, Lemaître F, Terriac E, et al. Dynamic in situ cytometry uncovers T cell receptor signaling during immunological synapses and kinapses in vivo. Immunity 2012; 37:351–363. [38]

Mundinger GS, Narushima M, Hui-Chou HG, Jones LS, et al. Infrared Fluorescence Imaging of Lymphatic Regeneration in Nonhuman Primate Facial Vascularized Composite Allografts. Ann Plast Surg 2012; 68:314–319. View Full Text | PubMed | CrossRef

Obeidat MA, Luyckx VA, Grebe SO, Jhangri GS, et al. Post-transplant nuclear renal scans correlate with renal injury biomarkers and early allograft outcomes. Nephrol Dial Transplant 2011; 26:3038–3045. View Full Text | PubMed | CrossRef

▪▪. Orth JD, Kohler RH, Foijer F, et al. Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Res 2011; 71:4608–4616. [39]

▪▪. Reiner T, Thurber G, Gaglia J, et al. Accurate measurement of pancreatic islet beta-cell mass using a second generation fluorescent exendin-4 analog. Proc Natl Acad Sci USA 2011; 108:12815–12820. [40]

Rigamonti C, Fraquelli M, Bastiampillai AJ, Caccamo L, et al. Transient elastography identifies liver recipients with nonviral graft disease after transplantation: A guide for liver biopsy. Liver Transplant 2012; 18:566–576. View Full Text | PubMed | CrossRef

Sachdeva R, Malik S, Seib PM, Frazier EA, et al. Doppler tissue imaging and catheter-derived measures are not independent predictors of rejection in pediatric heart transplant recipients. Int J Cardiovasc Imaging 2011; 27:947–954.

Sandrasegaran K, Ramaswamy R, Ghosh S, Tahir B, et al. Diffusion-weighted MRI of the transplanted liver. Clin Radiol 2011; 66:820–825. PubMed | CrossRef

Sargsyan SA, Serkova NJ, Renner B, Hasebroock KM, et al. Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis. Kidney Int 2012; 81:152–159. PubMed | CrossRef

Shi J, Pan CZ, Shu XH, Sun MM, et al. The role of speckle tracking imaging in the noninvasive detection of acute rejection after heterotopic cardiac transplantation in rats. Acta Cardiol 2011; 66:779–785. PubMed

Stock KF, Klein BS, Cong MTV, Regenbogen C, et al. ARFI-based tissue elasticity quantification and kidney graft dysfunction: First clinical experiences. Clin Hemorheol Microcirc 2011; 49:527–535. PubMed

Sun QQ, Zhang MC, Xie KN, Li X, et al. Endothelial injury in transplant glomerulopathy is correlated with transcription factor T-bet expression. Kidney Int 2012; 82:321–329. PubMed | CrossRef

Takahashi H, Ruiz P, Ricordi C, De lacruz V, et al. Quantitative In Situ Analysis of FoxP3(+) T Regulatory Cells on Transplant Tissue Using Laser Scanning Cytometry. Cell Transplant 2012; 21:113–125. PubMed | CrossRef

Van dermeer FQ, Manning MA, Frazier AA, Wong-You-Cheong JJ. Imaging of Whole-Organ Pancreas Transplants. Radiographics 2012; 32:411–435. PubMed | CrossRef

Xiao WB, Xu JJ, Wang QD, Xu Y, et al. Functional evaluation of transplanted kidneys in normal function and acute rejection using BOLD MR imaging. Eur J Radiol 2012; 81:838–845. PubMed | CrossRef

Yamamoto A, Zhang JL, Rusinek H, Chandarana H, et al. Quantitative Evaluation of Acute Renal Transplant Dysfunction with Low-Dose Three-dimensional MR Renography. Radiology 2011; 260:781–789. PubMed | CrossRef

Zhang B, Jiang BA, Chen Y, Huang H, et al. Detection of viability of transplanted beta cells labeled with a novel contrast agent - polyvinylpyrrolidone-coated superparamagnetic iron oxide nanoparticles by magnetic resonance imaging. Contrast Media Mol Imaging 2012; 7:35–44.

Zhang JS, Razavian M, Tavakoli S, Nie L, et al. Molecular Imaging of Vascular Endothelial Growth Factor Receptors in Graft Arteriosclerosis. Arterioscler Thromb Vasc Biol 2012; 32:1849. View Full Text | PubMed | CrossRef

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Rethinking the multiple roles of B cells in organ transplantation

Review: (pp. 13–21)

Acevedo MJ, Caro-Oleas JL, Alvarez-Marquez AJ, Sobrino JM, et al. Antibodies against heterogeneous nuclear ribonucleoprotein K in patients with cardiac allograft vasculopathy. J Heart Lung Transplant 2011; 30:1051–1059. PubMed | CrossRef

Adams AB, Newell KA. B cells in clinical transplantation tolerance. Semin Immunol 2012; 24:92–95. PubMed | CrossRef

Baldwin WM, Halushka MK, Valujskikh A, Fairchild RL. B cells in cardiac transplants: From clinical questions to experimental models. Semin Immunol 2012; 24:122–130. PubMed | CrossRef

▪▪. Blair PA, Norena LY, Flores-Borja F, et al. CD19+CD24hi CD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity 2010; 32:129–140. [69]

▪▪. Cherukuri A, Salama AD, Carter C, et al. An analysis of lymphocyte phenotype after steroid avoidance with either alemtuzumab or basiliximab induction in renal transplantation. Am J Transplant 2012; 12:919–931. [104]

Chikamoto H, Sugawara N, Akioka Y, Shimizu T, et al. Immunohistological study of a pediatric patient with plasma cell-rich acute rejection. Clin Transplant 2012; 26:54–57. View Full Text | PubMed | CrossRef

Conway J, Manlhiot C, Allain-Rooney T, McCrindle BW, et al. Development of Donor-Specific Isohemagglutinins Following Pediatric ABO-Incompatible Heart Transplantation. Am J Transplant 2012; 12:888–895. View Full Text | PubMed | CrossRef

Cowan ML, Sciammas R, Chong AS. Experimental models of B cell tolerance in transplantation. Semin Immunol 2012; 24:77–85. PubMed | CrossRef

▪▪. Danger R, Pallier A, Giral M, et al. Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant. J Am Soc Nephrol 2012; 23:597–606. [82]

De La Torre I, Leandro MJ, Valor L, Becerra E, et al. Total serum immunoglobulin levels in patients with RA after multiple B-cell depletion cycles based on rituximab: relationship with B-cell kinetics. Rheumatology 2012; 51:833–840.

Dick AAS, Horslen S. Antibody-mediated rejection after intestinal transplantation. Curr Opin Organ Transpl 2012; 17:250–257. View Full Text | PubMed | CrossRef

▪▪. Di Lillo DJ, Griffiths R, Seshan SV, et al. B lymphocytes differentially influence acute and chronic allograft rejection in mice. J Immunol 2011; 186:2643–2654. [62]

▪. Ding Q, Yeung M, Camirand G, et al. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Investig 2011; 121:3645–3656. [71]

Engels EA, Preiksaitis J, Zingone A, Landgren O. Circulating Antibody Free Light Chains and Risk of Posttransplant Lymphoproliferative Disorder. Am J Transplant 2012; 12:1268–1274. View Full Text | PubMed | CrossRef

Ferrari-Lacraz S, Tiercy JM, Villard J. Detection of anti-HLA antibodies by solid-phase assay in kidney transplantation: friend or foe? Tissue Antigens 2012; 79:315–325.

Fukami N, Ramachandran S, Narayanan K, Liu W, et al. Mechanism of Accommodation in a Sensitized Human Leukocyte Antigen Transgenic Murine Cardiac Transplant Model. Transplantation 2012; 93:364–372. View Full Text | PubMed | CrossRef

Galvani S, Trayssac M, Auge N, Thiers JC, et al. A Key Role for Matrix Metalloproteinases and Neutral Sphingomyelinase-2 in Transplant Vasculopathy Triggered by Anti-HLA Antibody. Circulation 2011; 124:2725. View Full Text | PubMed | CrossRef

▪▪. Hanaway MJ, Woodle ES, Mulgaonkar S, et al. Alemtuzumab induction in renal transplantation. N Engl J Med 2011; 364:1909–1919. [102]

▪▪. Heidt S, Hester J, Shankar S, et al. B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naive B cells. Am J Transplant 2012; 12:1784–1792. [103]

Hubscher SG. Antibody-mediated rejection in the liver allograft. Curr Opin Organ Transpl 2012; 17:280–286. View Full Text | PubMed

Iwasaki K, Miwa Y, Ogawa H, Yazaki S, et al. Comparative Study on Signal Transduction in Endothelial Cells After Anti-A/B and Human Leukocyte Antigen Antibody Reaction: Implication of Accommodation. Transplantation 2012; 93:390–397. View Full Text | PubMed | CrossRef

▪▪. Iwata Y, Matsushita T, Horikawa M, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood 2011; 117:530–541. [68]

Kamburova EG, Koenen H, Boon L, Hilbrands LB, et al. In Vitro Effects of Rituximab on the Proliferation, Activation and Differentiation of Human B Cells. Am J Transplant 2012; 12:341–350. View Full Text | PubMed | CrossRef

▪▪. Kamburova EG, Koenen HJ, Boon L, et al. In vitro effects of rituximab on the proliferation, activation and differentiation of human B cells. Am J Transplant 2012; 12:341–350. [87]

▪. La Mattina JC, Mezrich JD, Hofmann RM, et al. Alemtuzumab as compared to alternative contemporary induction regimens. Transpl Int 2012; 25:518–526. [109]

▪▪. Le Texier L, Thebault P, Lavault A, et al. Long-term allograft tolerance is characterized by the accumulation of B cells exhibiting an inhibited profile. Am J Transplant 2011; 11:429–438. [70]

Miyoshi K, Sano Y, Yamane M, Toyooka S, et al. Elevation of Antidonor Immunoglobulin M Levels Precedes Acute Lung Transplant Rejection. Ann Thorac Surg 2011; 92:1233–1238. View Full Text | PubMed | CrossRef

Mohiuddin MM, Corcoran PC, Singh AK, Azimzadeh A, et al. B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months. Am J Transplant 2012; 12:763–771. View Full Text | PubMed | CrossRef

Moreno C, Burgos L, Perez-Robles C, Delgado JA, et al. Predictive value of the Luminex single antigen panel for detecting flow cytometry cross-match positivity. Hum Immunol 2012; 73:517–521. PubMed | CrossRef

▪. Morrow WR, Frazier EA, Mahle WT, et al. Rapid reduction in donor-specific antihuman leukocyte antigen antibodies and reversal of antibody-mediated rejection with bortezomib in pediatric heart transplant patients. Transplantation 2012; 93:319–324. [96]

Naemi FMA, Ali S, Kirby JA. Antibody-mediated allograft rejection: The emerging role of endothelial cell signalling and transcription factors. Transpl Immunol 2011; 25:96–103. PubMed | CrossRef

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Sadaka B, Alloway RR, Shields AR, Schmidt NM, et al. Proteasome Inhibition for Antibody-Mediated Allograft Rejection. Semin Hematol 2012; 49:263–269.

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Zarkhin V, Sarwal MM. The coin toss of B cells in rejection and tolerance: Danger versus defense. Semin Immunol 2012; 24:86–91. PubMed | CrossRef

Zhang XH, Valenzuela NM, Reed EF. HLA class I antibody-mediated endothelial and smooth muscle cell activation. Curr Opin Organ Transpl 2012; 17:446–451. View Full Text | PubMed | CrossRef

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Molecular diagnosis of rejection

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Ashokkumar C, Ningappa M, Ranganathan S, Higgs BW, et al. Increased Expression of Peripheral Blood Leukocyte Genes Implicate CD14(+) Tissue Macrophages in Cellular Intestine Allograft Rejection. Am J Pathol 2011; 179:1929–1938. PubMed | CrossRef

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Bestard O, Cunetti L, Cruzado JM, Lucia M, et al. Intragraft Regulatory T Cells in Protocol Biopsies Retain Foxp3 Demethylation and Are Protective Biomarkers for Kidney Graft Outcome. Am J Transplant 2011; 11:2162–2172. View Full Text | PubMed | CrossRef

Chen G, Huang JB, Mi J, He YF, et al. Characterization of acute renal allograft rejection by proteomic analysis of renal tissue in rat. Mol Biol Rep 2012; 39:1315–1322. PubMed | CrossRef

Chen G, Mi J, Xiao MZ, Fu YR. PDIA3 mRNA expression and IL-2, IL-4, IL-6, and CRP levels of acute kidney allograft rejection in rat. Mol Biol Rep 2012; 39:5233–5238. PubMed | CrossRef

Chen JH, Wen H, Liu J, Yu C, et al. Metabonomics study of the acute graft rejection in rat renal transplantation using reversed-phase liquid chromatography and hydrophilic interaction chromatography coupled with mass spectrometry. Mol Biosyst 2012; 8:871–878. PubMed

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Dharnidharka VR. Less invasive biomarkers of acute rejection: Reaching the elusive clinic. Pediatr Transplant 2012; 16:308–309. View Full Text | PubMed | CrossRef

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Garcia-Roca P, Vargas YA, Fuentes Y, Hernandez AM, et al. Serum soluble interleukin 2 receptor (sIL-2R) as a marker of acute rejection in renal transplant children. Pediatr Transplant 2012; 16:274–279. View Full Text | PubMed | CrossRef

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Johnston O, Cassidy H, O'Connell S, O'Riordan A, et al. Identification of beta 2-microglobulin as a urinary biomarker for chronic allograft nephropathy using proteomic methods. Proteom Clin Appl 2011; 5:422–431.

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Mannon RB. Macrophages: contributors to allograft dysfunction, repair, or innocent bystanders? Curr Opin Organ Transpl 2012; 17:20–25.

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Neujahr DC, Perez SD, Mohammed A, Ulukpo O, et al. Cumulative Exposure to Gamma Interferon-Dependent Chemokines CXCL9 and CXCL10 Correlates with Worse Outcome After Lung Transplant. Am J Transplant 2012; 12:438–446.

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Pisitkun T, Gandolfo MT, Das S, Knepper MA, et al. Application of systems biology principles to protein biomarker discovery: Urinary exosomal proteome in renal transplantation. Proteom Clin Appl 2012; 6:268–278.

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Viglietti D, Peraldi MN. Cytopenias following kidney transplantation. Nephrol Ther 2011; 7:474–478. PubMed

Wang MM, Jin Q, Tu HY, Mao YY, et al. Detection of renal allograft dysfunction with characteristic protein fingerprint by serum proteomic analysis. Int Urol Nephrol 2011; 43:1009–1017. PubMed | CrossRef

Wei L, Wang M, Qu X, Mah A, et al. Differential Expression of MicroRNAs During Allograft Rejection. Am J Transplant 2012; 12:1113–1123. View Full Text | PubMed | CrossRef

Weigt SS, Derhovanessian A, Liao E, Hu S, et al. CXCR3 Chemokine Ligands During Respiratory Viral Infections Predict Lung Allograft Dysfunction. Am J Transplant 2012; 12:477–484. View Full Text | PubMed | CrossRef

Xie L, Ichimaru N, Morita M, Chen JJ, et al. Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance. Liver Transplant 2012; 18:444–454.

Yaghobi R, Karimi MH, Namayandeh M, Geramizadeh B, et al. The Association of Polymorphisms in Cytokine Genes with Acute Rejection and the Pathogenesis of Hepatitis B and C in Liver Transplant Recipients. Labmedicine 2012; 43:181–188.

Zarkhin V, Sarwal MM. The coin toss of B cells in rejection and tolerance: Danger versus defense. Semin Immunol 2012; 24:86–91. PubMed | CrossRef

Zhang JS, Razavian M, Tavakoli S, Nie L, et al. Molecular Imaging of Vascular Endothelial Growth Factor Receptors in Graft Arteriosclerosis. Arterioscler Thromb Vasc Biol 2012; 32:1849. View Full Text | PubMed | CrossRef

Ziegler ME, Chen TC, Le Blanc JF, Wei XL, et al. Apolipoprotein A1 and C-Terminal Fragment of alpha-1 Antichymotrypsin Are Candidate Plasma Biomarkers Associated With Acute Renal Allograft Rejection. Transplantation 2011; 92:388–395. View Full Text | PubMed | CrossRef

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T cell structure and allograft rejection

Engels B, Chervin AS, Sant AJ, Kranz DM, et al. Long-term Persistence of CD4(+) but Rapid Disappearance of CD8(+) T Cells Expressing an MHC Class I-restricted TCR of Nanomolar Affinity. Mol Ther 2012; 20:652–660. PubMed | CrossRef

Fleischhauer K, Shaw BE, Gooley T, Malkki M, et al. Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study. Lancet Oncol 2012; 13:366–374. PubMed | CrossRef

Smith C, Miles JJ, Khanna R. Advances in Direct T-Cell Alloreactivity: Function, Avidity, Biophysics and Structure. Am J Transplant 2012; 12:15–26. View Full Text | PubMed | CrossRef

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Stem cell transplantation
Machine perfusion in organ transplantation: a tool for ex-vivo graft conditioning with mesenchymal stem cells?

Review: (pp. 24–33)

▪▪. Balfoussia D, Yerrakalva D, Hamaoui K, Papalois V. Advances in machine perfusion graft viability assessment in kidney, liver, pancreas, lung, and heart transplant. Exp Clin Transplant 2012; 10:87–100. [08]

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Hu N, Zhang YY, Gu HW, Guan HJ. Effects of Bone Marrow Mesenchymal Stem Cells on Cell Proliferation and Growth Factor Expression of Limbal Epithelial Cells in vitro. Ophthalmic Res 2012; 48:82–88. PubMed | CrossRef

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Ischemia–reperfusion injury: beneficial effects of mesenchymal stromal cells

Review: (pp. 34–43)

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The role of mesenchymal stromal cells in chronic transplant rejection after solid organ transplantation

Review: (pp. 44–50)

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Yeh SP, Lo WJ, Lin CL, Liao YM, et al. Anti-leukemic therapies induce cytogenetic changes of human bone marrow-derived mesenchymal stem cells. Ann Hematol 2012; 91:163–172. View Full Text | PubMed | CrossRef

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Mesenchymal stromal cells to promote solid organ transplantation tolerance

Review: (pp. 51–58)

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Mesenchymal stromal cells as a means of controlling pathological T-cell responses in allogeneic islet transplantation

Review: (pp. 59–64)

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Gimeno ML, Hyon SH, Argibay PF. Cell therapy for diabetes mellitus: Beyond stem cells. Med-Buenos Aires 2011; 71:267–273.

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Generation of mesenchymal stem cells as a medicinal product in organ transplantation

Review: (pp. 65–70)

Argolo Neto NM, Del Carlo RJ, Monteiro BS, Nardi NB, et al. Role of autologous mesenchymal stem cells associated with platelet-rich plasma on healing of cutaneous wounds in diabetic mice. Clin Exp Dermatol 2012; 37:544–553. View Full Text | PubMed | CrossRef

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Zeng X, Zeng YS, Ma YH, Lu LY, et al. Bone Marrow Mesenchymal Stem Cells in a Three-Dimensional Gelatin Sponge Scaffold Attenuate Inflammation, Promote Angiogenesis, and Reduce Cavity Formation in Experimental Spinal Cord Injury. Cell Transplant 2011; 20:1881–1899. PubMed | CrossRef

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Mesenchymal stem cells in organ and tissue transplantation: one for all seasons?

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Allogeneic stem cell transplant, GVHD, umbilical cord blood transplant

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Pancreas transplantation
Immunological monitoring after pancreas transplantation

Review: (pp. 71–75)

Browne S, Gill J, Dong J, Rose C, et al. The Impact of Pancreas Transplantation on Kidney Allograft Survival. Am J Transplant 2011; 11:1951–1958. View Full Text | PubMed | CrossRef

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Caillard S, Lamy FX, Quelen C, Dantal J, et al. Epidemiology of Posttransplant Lymphoproliferative Disorders in Adult Kidney and Kidney Pancreas Recipients: Report of the French Registry and Analysis of Subgroups of Lymphomas. Am J Transplant 2012; 12:682–693. View Full Text | PubMed | CrossRef

del Rio ML, Jones ND, Buhler L, Norris P, et al. Selective Blockade of Herpesvirus Entry Mediator-B and T Lymphocyte Attenuator Pathway Ameliorates Acute Graft-versus-Host Reaction. J Immunol 2012; 188:4885–4896. PubMed | CrossRef

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Koyama S, Tomimatsu T, Kanagawa T, Daimon E, et al. Successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor: The first case report in Japan. J Obstet Gynaecol Res 2011; 37:1711–1716. View Full Text | PubMed | CrossRef

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Pavlakis M, Hanto DW. Clinical pathways in transplantation: a review and examples from Beth Israel Deaconess Medical Center. Clin Transplant 2012; 26:382–386. View Full Text | PubMed | CrossRef

Pengel LHM, Liu LQ, Morris PJ. Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials. Transpl Int 2011; 24:1216–1230.

Perosa M, Crescentini F, Noujaim H, Mota LT, et al. Over 500 pancreas transplants by a single team in Sao Paulo, Brazil. Clin Transplant 2011; 25:E422–E429. View Full Text | PubMed

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Ricart MJ, Oppenheimer F, Andres A, Morales JM, et al. Enteric-coated mycophenolate sodium in de novo and maintenance kidney-pancreas transplant recipients. Clin Transplant 2012; 26:424–431. View Full Text | PubMed | CrossRef

Tsukamoto H, Chernogorova P, Ayata K, Gerlach UV, et al. Deficiency of CD73/ecto-5 '-nucleotidase in mice enhances acute graft-versus-host disease. Blood 2012; 119:4554–4564. PubMed | CrossRef

Uemura T, Ramprasad V, Matsushima K, Shike H, et al. Single Dose of Alemtuzumab Induction With Steroid-Free Maintenance Immunosuppression in Pancreas Transplantation. Transplantation 2011; 92:678–685. View Full Text | PubMed | CrossRef

Yamazaki T, Aoki K, Heike Y, Kim SW, et al. Real-time in vivo cellular imaging of graft-versus-host disease and immunomodulatory reagents. Immunol Lett 2012; 144:33–40. PubMed | CrossRef

Zyromski NJ, Baker MS. Summary of at the 45th Annual Pancreas Club Meeting Proceedings. J Gastrointest Surg 2012; 16:935–945. PubMed | CrossRef

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Trends in immunosuppression after pancreas transplantation: what is in the pipeline?

Review: (pp. 76–82)

Balamurugan AN, Loganathan G, Bellin MD, Wilhelm JJ, et al. A New Enzyme Mixture to Increase the Yield and Transplant Rate of Autologous and Allogeneic Human Islet Products. Transplantation 2012; 93:693–702. View Full Text | PubMed | CrossRef

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Browne S, Gill J, Dong J, Rose C, et al. The Impact of Pancreas Transplantation on Kidney Allograft Survival. Am J Transplant 2011; 11:1951–1958. View Full Text | PubMed | CrossRef

Burke GW, Vendrame F, Pileggi A, Ciancio G, et al. Recurrence of Autoimmunity Following Pancreas Transplantation. Curr Diabetes Rep 2011; 11:413–419. PubMed | CrossRef

Caillard S, Lamy FX, Quelen C, Dantal J, et al. Epidemiology of Posttransplant Lymphoproliferative Disorders in Adult Kidney and Kidney Pancreas Recipients: Report of the French Registry and Analysis of Subgroups of Lymphomas. Am J Transplant 2012; 12:682–693. View Full Text | PubMed | CrossRef

del Rio ML, Jones ND, Buhler L, Norris P, et al. Selective Blockade of Herpesvirus Entry Mediator-B and T Lymphocyte Attenuator Pathway Ameliorates Acute Graft-versus-Host Reaction. J Immunol 2012; 188:4885–4896. PubMed | CrossRef

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Kosieradzki M, Lisik W, Rowinski W, Malkowski P. Progress in abdominal organ transplantation. Med Sci Monitor 2011; 17:RA282–RA291.

Koyama S, Tomimatsu T, Kanagawa T, Daimon E, et al. Successful pregnancy after simultaneous pancreas-kidney transplantation from a brain-dead donor: The first case report in Japan. J Obstet Gynaecol Res 2011; 37:1711–1716. View Full Text | PubMed | CrossRef

Leventhal J, Huang YM, Xu H, Goode I, et al. Novel regulatory therapies for prevention of Graft-versus-host disease - art. no. 48. BMC Med 2012; 10:15.

Lu QY, Zhang LF, Moro A, Chen MC, et al. Detection of Baicalin Metabolites Baicalein and Oroxylin-A in Mouse Pancreas and Pancreatic Xenografts. Pancreas 2012; 41:571–576. View Full Text | PubMed | CrossRef

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Pengel LHM, Liu LQ, Morris PJ. Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials. Transpl Int 2011; 24:1216–1230.

Piao SG, Bae SK, Lim SW, Song JH, et al. Drug Interaction Between Cyclosporine and mTOR Inhibitors in Experimental Model of Chronic Cyclosporine Nephrotoxicity and Pancreatic Islet Dysfunction. Transplantation 2012; 93:383–389. View Full Text | PubMed | CrossRef

Ricart MJ, Oppenheimer F, Andres A, Morales JM, et al. Enteric-coated mycophenolate sodium in de novo and maintenance kidney-pancreas transplant recipients. Clin Transplant 2012; 26:424–431. View Full Text | PubMed | CrossRef

Saudek F, Berney T, Boucek P. 13(th) World Congress of the International Pancreas and Islet Transplant Association (IPITA). Transplant Proc 2011; 43:3155. PubMed | CrossRef

Su Y, Huang XY, Wang S, Min WP, et al. Double negative Treg cells promote nonmyeloablative bone marrow chimerism by inducing T-cell clonal deletion and suppressing NK cell function. Eur J Immunol 2012; 42:1216–1225. PubMed | CrossRef

Uemura T, Ramprasad V, Matsushima K, Shike H, et al. Single Dose of Alemtuzumab Induction With Steroid-Free Maintenance Immunosuppression in Pancreas Transplantation. Transplantation 2011; 92:678–685. View Full Text | PubMed | CrossRef

Wood KJ, Goto R. Mechanisms of Rejection: Current Perspectives. Transplantation 2012; 93:1–10.

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Donor risk factors, retrieval technique, preservation and ischemia/reperfusion injury in pancreas transplantation

Review: (pp. 83–88)

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Jiang XF, Qian TL, Linn T, Cao LQ, et al. Islet isolation and purification from inbred Wuzhishan miniature pigs. Xenotransplantation 2012; 19:159–165. View Full Text | PubMed

Matsumoto S, Takita M, Shimoda M, Itoh T, et al. Usefulness of the Secretory Unit of Islet Transplant Objects (SUITO) Index for Evaluation of Clinical Autologous Islet Transplantation. Transplant Proc 2011; 43:3246–3249. PubMed | CrossRef

Messersmith EE, Arrington C, Alexander C, Orlowski JP, et al. Development of Donor Yield Models. Am J Transplant 2011; 11:2075–2084. View Full Text | PubMed | CrossRef

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Naziruddin B, Matsumoto S, Noguchi H, Takita M, et al. Improved Pancreatic Islet Isolation Outcome in Autologous Transplantation for Chronic Pancreatitis. Cell Transplant 2012; 21:553–558. PubMed | CrossRef

Niclauss N, Wojtusciszyn A, Morel P, Demuylder-Mischler S, et al. Comparative Impact on Islet Isolation and Transplant Outcome of the Preservation Solutions Institut Georges Lopez-1, University of Wisconsin, and Celsior. Transplantation 2012; 93:703–708. View Full Text | PubMed | CrossRef

Otsuki K, Yoshikawa K, Kenmochi T, Maruyama M, et al. Evaluation of Segmental Pancreatic Function Using 11C-Methionine Positron Emission Tomography for Safe Living Donor Operation of Pancreas Transplantation. Transplant Proc 2011; 43:3273–3276. PubMed | CrossRef

Park JB, Kim YH, Song KB, Chung YS, et al. Single-Center Experience with Pancreas Transplantation. Transplant Proc 2012; 44:925–928. PubMed | CrossRef

Pavlakis M, Hanto DW. Clinical pathways in transplantation: a review and examples from Beth Israel Deaconess Medical Center. Clin Transplant 2012; 26:382–386. View Full Text | PubMed | CrossRef

Perosa M, Crescentini F, Noujaim H, Mota LT, et al. Over 500 pancreas transplants by a single team in Sao Paulo, Brazil. Clin Transplant 2011; 25:E422–E429. View Full Text | PubMed

Porubsky M, Powelson JA, Selzer DJ, Mujtaba MA, et al. Pancreas transplantation after bariatric surgery. Clin Transplant 2012; 26:E1–E6. View Full Text | PubMed | CrossRef

▪. Reich DJ, Mulligan DC, Abt PL, et al. ASTS recommended practice guidelines for controlled donation after cardiac death organ procurement and transplantation. Am J Transplant 2009; 9:2004–2011. [30]

Saudek F, Berney T, Boucek P. 13(th) World Congress of the International Pancreas and Islet Transplant Association (IPITA). Transplant Proc 2011; 43:3155. PubMed | CrossRef

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Wang Y, Paushter D, Wang SS, Barbaro B, et al. Highly Purified Versus Filtered Crude Collagenase: Comparable Human Islet Isolation Outcomes. Cell Transplant 2011; 20:1817–1825. PubMed | CrossRef

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Zyromski NJ, Baker MS. Summary of at the 45th Annual Pancreas Club Meeting Proceedings. J Gastrointest Surg 2012; 16:935–945. PubMed | CrossRef

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Risk factors for and management of graft pancreatitis

Review: (pp. 89–96)

Banga N, Hadjianastassiou VG, Mamode N, Calder F, et al. Outcome of surgical complications following simultaneous pancreas-kidney transplantation. Nephrol Dial Transplant 2012; 27:1658–1663. View Full Text | PubMed | CrossRef

Berrie JL, Kmieciak M, Sabo RT, Roberts CH, et al. Distinct Oligoclonal T Cells Are Associated With Graft Versus Host Disease After Stem-Cell Transplantation. Transplantation 2012; 93:949–957. View Full Text | PubMed | CrossRef

Biglarnia AR, Emanuelsson C, Quach M, Clausen F, et al. The free radical scavenger S-PBN significantly prolongs DSG-mediated graft survival in experimental xenotransplantation. Xenotransplantation 2012; 19:166–176. View Full Text | PubMed | CrossRef

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Cantarovich D, De Amicis S, Akl A, Devys A, et al. Posttransplant Donor-Specific Anti-HLA Antibodies Negatively Impact Pancreas Transplantation Outcome. Am J Transplant 2011; 11:2737–2746. View Full Text | PubMed | CrossRef

Chatzizacharias NA, Vaidya A, Sinha S, Sharples E, et al. Risk analysis for deterioration of renal function after pancreas alone transplant. Clin Transplant 2012; 26:387–392. View Full Text | PubMed | CrossRef

Chatzizacharias NA, Vaidya A, Sinha S, Smith R, et al. Renal function in type 1 diabetics one year after successful pancreas transplantation. Clin Transplant 2011; 25: E509–E515. View Full Text | PubMed | CrossRef

Deboudt C, Branchereau J, Luyckx F, Rigaud J, et al. Pancreas transplantation and venous thrombosis: Multivariate analysis of risk factors. Prog Urol 2012; 22:402–407. PubMed | CrossRef

Donegan D, Hickey DP, Smith D. Hypoglycemia After Simultaneous Pancreas-Kidney Transplant Fact or Factitious? Pancreas 2012; 41:974–976.

Drachenberg CB, Torrealba JR, Nankivell BJ, Rangel EB, et al. Guidelines for the Diagnosis of Antibody-Mediated Rejection in Pancreas Allografts-Updated Banff Grading Schema. Am J Transplant 2011; 11:1792–1802.

Enestvedt CK, Levine MH. Abdominal Pain, Fever and Free Air One Year Post Simultaneous Pancreas-Kidney Transplant. Am J Transplant 2012; 12:1657–1659. View Full Text | PubMed | CrossRef

Farney AC, Rogers J, Stratta RJ. Pancreas graft thrombosis: causes, prevention, diagnosis, and intervention. Curr Opin Organ Transpl 2012; 17:87–92. View Full Text | PubMed | CrossRef

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Garcia-Roca R, Samame J, Garcia-Criado MA, Real MI, et al. Preservation of Pancreas Graft Function After Complete Venous Thrombosis: Report of Four Cases Treated Conservatively. Transplantation 2012; 93:214–218.

Gimenez JM, Bluth EI, Simon A, Troxclair L. Evaluation of Pancreatic Allografts With Sonography. J Ultrasound Med 2012; 31:1041–1051. PubMed

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Grossi PA, Righi E, Dalla Gasperina D, Donati D, et al. Report of Four Simultaneous Pancreas-Kidney Transplants in HIV-Positive Recipients With Favorable Outcomes. Am J Transplant 2012; 12:1039–1045.

Gruessner AC, Sutherland DER, Gruessner RWG. Long-term outcome after pancreas transplantation. Curr Opin Organ Transpl 2012; 17:100–105. View Full Text | PubMed | CrossRef

Huang E, Wiseman A, Okumura S, Kuo HT, et al. Outcomes of Preemptive Kidney With or Without Subsequent Pancreas Transplant Compared With Preemptive Simultaneous Pancreas/Kidney Transplantation. Transplantation 2011; 92:1115–1122. View Full Text | PubMed

Kleespies A, Mikhailov M, Khalil PN, Preissler G, et al. Enteric conversion after pancreatic transplantation: resolution of symptoms and long-term results. Clin Transplant 2011; 25:549–560. View Full Text | PubMed | CrossRef

La Mattina J, Sollinger H, Becker Y, Mezrich J, et al. Long-Term Pancreatic Allograft Survival After Renal Retransplantation in Prior Simultaneous Pancreas-Kidney Recipients. Am J Transplant 2012; 12:937–946. View Full Text | PubMed

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Lu QY, Zhang LF, Moro A, Chen MC, et al. Detection of Baicalin Metabolites Baicalein and Oroxylin-A in Mouse Pancreas and Pancreatic Xenografts. Pancreas 2012; 41:571–576. View Full Text | PubMed | CrossRef

Luan FL, Kommareddi M, Cibrik DM, Samaniego M, et al. The time interval between kidney and pancreas transplantation and the clinical outcomes of pancreas after kidney transplantation. Clin Transplant 2012; 26:403–410. View Full Text | PubMed | CrossRef

Margreiter C, Aigner F, Resch T, Berenji AK, et al. Enteroscopic Biopsies in the Management of Pancreas Transplants: A Proof of Concept Study for a Novel Monitoring Tool. Transplantation 2012; 93:207–213. View Full Text | PubMed | CrossRef

Mindlova M, Boucek P, Saudek F, Skibova J, et al. Prevalence and risk factors of polyomavirus BK replication in simultaneous pancreas/kidney transplant recipients from a single transplant center. Clin Transplant 2012; 26:267–274. View Full Text | PubMed | CrossRef

Miyagi S, Sekiguchi S, Kawagishi N, Akamatsu Y, et al. Nonmarginal-Donor Duodenal Ulcers Caused by Rejection After Simultaneous Pancreas and Kidney Transplantation: A Case Report. Transplant Proc 2011; 43:3292–3295. PubMed | CrossRef

Mujtaba M, Fridell J, Sharfuddin A, Kandula P, et al. BK virus nephropathy in simultaneous pancreas kidney transplant: a potentially preventable cause of kidney allograft loss. Clin Transplant 2012; 26:E87–E93. View Full Text | PubMed | CrossRef

Naziruddin B, Matsumoto S, Noguchi H, Takita M, et al. Improved Pancreatic Islet Isolation Outcome in Autologous Transplantation for Chronic Pancreatitis. Cell Transplant 2012; 21:553–558. PubMed | CrossRef

Nikolic V, Velickovic S, Popovic A. Amine activators influence on grafting reaction between methacrylic acid and starch. Carbohydr Polym 2012; 88:1407–1413. PubMed | CrossRef

Norman SP, Kommareddi M, Ojo AO, Luan FL. Early Pancreas Graft Failure Is Associated With Inferior Late Clinical Outcomes After Simultaneous Kidney-Pancreas Transplantation. Transplantation 2011; 92:796–801. View Full Text | PubMed | CrossRef

Occhipinti M, Lampasona V, Vistoli F, Bazzigaluppi E, et al. Zinc Transporter 8 Autoantibodies Increase the Predictive Value of Islet Autoantibodies for Function Loss of Technically Successful Solitary Pancreas Transplant. Transplantation 2011; 92:674–677. View Full Text | PubMed | CrossRef

Papadimitriou JC, Drachenberg CB. Distinctive morphological features of antibody-mediated and T-cell-mediated acute rejection in pancreas allograft biopsies. Curr Opin Organ Transpl 2012; 17:93–99. View Full Text | PubMed | CrossRef

Piao SG, Bae SK, Lim SW, Song JH, et al. Drug Interaction Between Cyclosporine and mTOR Inhibitors in Experimental Model of Chronic Cyclosporine Nephrotoxicity and Pancreatic Islet Dysfunction. Transplantation 2012; 93:383–389. View Full Text | PubMed | CrossRef

Siddique A, Kowdley KV. Approach to a Patient with Elevated Serum Alkaline Phosphatase. Clin Liver Dis 2012; 16: 199. PubMed | CrossRef

Smail N, Paraskevas S, Tan XM, Metrakos P, et al. Renal function in recipients of pancreas transplant alone. Curr Opin Organ Transpl 2012; 17:73–79. View Full Text | PubMed | CrossRef

Takahashi H, Ruiz P, Ricordi C, De lacruz V, et al. Quantitative In Situ Analysis of FoxP3(+) T Regulatory Cells on Transplant Tissue Using Laser Scanning Cytometry. Cell Transplant 2012; 21:113–125. PubMed | CrossRef

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Van dermeer FQ, Manning MA, Frazier AA, Wong-You-Cheong JJ. Imaging of Whole-Organ Pancreas Transplants. Radiographics 2012; 32:411–435. PubMed | CrossRef

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Weir MR, Bartlett ST, Drachenberg CB. Eosinophilia as an early indicator of pancreatic allograft rejection. Clin Transplant 2012; 26:238–241. View Full Text | PubMed

Wood KJ, Goto R. Mechanisms of Rejection: Current Perspectives. Transplantation 2012; 93:1–10.

Yamauchi FI, Ortega CD, Blasbalg R, Rocha MS, et al. Multidetector CT Evaluation of the Postoperative Pancreas. Radiographics 2012; 32:743. PubMed | CrossRef

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Preoperative risk evaluation: where is the limit for recipients of a pancreatic graft?

Review: (pp. 97–101)

Boggi U, Signori S, Vistoli F, D'Imporzano S, et al. Laparoscopic Robot-Assisted Pancreas Transplantation: First World Experience. Transplantation 2012; 93:201–206. View Full Text | PubMed | CrossRef

Boggi U, Vistoli F, Amorese G, Giannarelli R, et al. Long-Term (5 Years) Efficacy and Safety of Pancreas Transplantation Alone in Type 1 Diabetic Patients. Transplantation 2012; 93:842–846. View Full Text | PubMed | CrossRef

Borot S, Niclauss N, Wojtusciszyn A, Brault C, et al. Impact of the Number of Infusions on 2-Year Results of Islet-After-Kidney Transplantation in the GRAGIL Network. Transplantation 2011; 92:1031–1038.

Cohen DJ, Ratner LE. Type 2 Diabetes: The Best Transplant Option Is Still Uncertain. Clin J Am Soc Nephrol 2012; 7:530–532. PubMed

Fridell JA, Mangus RS, Taber TE, Goble ML, et al. Growth of a nation part II: impact of recipient obesity on whole-organ pancreas transplantation. Clin Transplant 2011; 25: E366–E374. View Full Text | PubMed

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Kosieradzki M, Lisik W, Rowinski W, Malkowski P. Progress in abdominal organ transplantation. Med Sci Monitor 2011; 17:RA282–RA291.

Matsumoto S, Takita M, Shimoda M, Itoh T, et al. Usefulness of the Secretory Unit of Islet Transplant Objects (SUITO) Index for Evaluation of Clinical Autologous Islet Transplantation. Transplant Proc 2011; 43:3246–3249. PubMed | CrossRef

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Park JB, Kim YH, Song KB, Chung YS, et al. Single-Center Experience with Pancreas Transplantation. Transplant Proc 2012; 44:925–928. PubMed | CrossRef

Pavlakis M, Hanto DW. Clinical pathways in transplantation: a review and examples from Beth Israel Deaconess Medical Center. Clin Transplant 2012; 26:382–386. View Full Text | PubMed | CrossRef

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Porubsky M, Powelson JA, Selzer DJ, Mujtaba MA, et al. Pancreas transplantation after bariatric surgery. Clin Transplant 2012; 26:E1–E6. View Full Text | PubMed | CrossRef

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Shapiro AMJ. Strategies toward single-donor islets of Langerhans transplantation. Curr Opin Organ Transpl 2011; 16:627–631. View Full Text | PubMed | CrossRef

Sung RS, Abt PL, Desai DM, Garvey CA, et al. The right organ for the right recipient: the Ninth Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium. Clin Transplant 2011; 25:E592–E598. View Full Text | PubMed | CrossRef

Sutherland DER, Radosevich D, Gruessner R, Gruessner A, et al. Pushing the envelope: living donor pancreas transplantation. Curr Opin Organ Transpl 2012; 17:106–115. View Full Text | PubMed | CrossRef

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Wiseman AC. Pancreas transplant options for patients with type 1 diabetes mellitus and chronic kidney disease: simultaneous pancreas kidney or pancreas after kidney? Curr Opin Organ Transpl 2012; 17:80–86.

Wiseman AC, Gralla J. Simultaneous Pancreas Kidney Transplant versus Other Kidney Transplant Options in Patients with Type 2 Diabetes. Clin J Am Soc Nephrol 2012; 7:656–664. PubMed

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Follow-up of secondary diabetic complications after pancreas transplantation

Review: (pp. 102–110)

Assalino M, Genevay M, Morel P, Demuylder-Mischler S, et al. Recurrence of Type 1 Diabetes After Simultaneous Pancreas-Kidney Transplantation in the Absence of GAD and IA-2 Autoantibodies. Am J Transplant 2012; 12:492–495. View Full Text | PubMed | CrossRef

Balamurugan AN, Loganathan G, Bellin MD, Wilhelm JJ, et al. A New Enzyme Mixture to Increase the Yield and Transplant Rate of Autologous and Allogeneic Human Islet Products. Transplantation 2012; 93:693–702. View Full Text | PubMed | CrossRef

Barton FB, Rickels MR, Alejandro R, Hering BJ, et al. Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010. Diabetes Care 2012; 35:1436–1445. View Full Text | PubMed | CrossRef

Bellin MD, Barton FB, Heitman A, Harmon JV, et al. Potent Induction Immunotherapy Promotes Long-Term Insulin Independence After Islet Transplantation in Type 1 Diabetes. Am J Transplant 2012; 12:1576–1583. View Full Text | PubMed | CrossRef

▪. Boggi U, Amorese G, Marchetti P, Mosca F. Segmental live donor pancreas transplantation: review and critique of rationale, outcomes, and current recommendations. Clin Transplant 2011; 25:4–12. [23]

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Boggi U, Vistoli F, Amorese G, Giannarelli R, et al. Long-Term (5 Years) Efficacy and Safety of Pancreas Transplantation Alone in Type 1 Diabetic Patients. Transplantation 2012; 93:842–846. View Full Text | PubMed | CrossRef

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Chatzizacharias NA, Vaidya A, Sinha S, Smith R, et al. Renal function in type 1 diabetics one year after successful pancreas transplantation. Clin Transplant 2011; 25: E509–E515. View Full Text | PubMed | CrossRef

Cheng H, Zhang YC, Wolfe S, Valencia V, et al. Combinatorial treatment of bone marrow stem cells and stromal cell-derived factor 1 improves glycemia and insulin production in diabetic mice. Mol Cell Endocrinol 2011; 345:88–96. PubMed | CrossRef

Donegan D, Hickey DP, Smith D. Hypoglycemia After Simultaneous Pancreas-Kidney Transplant Fact or Factitious? Pancreas 2012; 41:974–976.

▪. Fioretto P, Najafian B, Sutherland DE, Mauer M. Tacrolimus and cyclosporine nephrotoxicity in native kidneys of pancreas transplant recipients. Clin J Am Soc Nephrol 2011; 6:101–106. [68]

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Gruessner AC, Sutherland DER, Gruessner RWG. Long-term outcome after pancreas transplantation. Curr Opin Organ Transpl 2012; 17:100–105. View Full Text | PubMed | CrossRef

▪. Huang E, Wiseman A, Okumura S, et al. Outcomes of preemptive kidney with or without subsequent pancreas transplant compared with preemptive simultaneous pancreas/kidney transplantation. Transplantation 2011; 92:1115–1122. [27]

Kawahara T, Kin T, Shapiro AMJ. A comparison of islet autotransplantation with allotransplantation and factors elevating acute portal pressure in clinical islet transplantation. J Hepato-Biliary-Pancreat Sci 2012; 19:281–288.

Kleespies A, Mikhailov M, Khalil PN, Preissler G, et al. Enteric conversion after pancreatic transplantation: resolution of symptoms and long-term results. Clin Transplant 2011; 25:549–560. View Full Text | PubMed | CrossRef

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Long D, Lu J, Luo L, Guo YJ, et al. Effects of Octreotide on Activated Pancreatic Stellate Cell-Induced Pancreas Graft Fibrosis in Rats. J Surg Res 2012; 176:248–259. PubMed | CrossRef

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Pour PM. A novel tissue for islet transplantation in diabetics. Pancreatology 2012; 12:57–60. PubMed | CrossRef

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Sekine K, Takebe T, Enomura M, Matsui C, et al. Regenerative Medicine Approach as an Alternative Treatment to Islet Transplantation. Transplant Proc 2012; 44:1104–1106. PubMed | CrossRef

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Shen J, Wan R, Hu GY, Yang LJ, et al. miR-15b and miR-16 induce the apoptosis of rat activated pancreatic stellate cells by targeting Bcl-2 in vitro. Pancreatology 2012; 12:91–99. PubMed | CrossRef

▪▪. Smail N, Paraskevas S, Tan X, et al. Renal function in recipients of pancreas transplant alone. Curr Opin Organ Transplant 2012; 17:73–79. [72]

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Infectious complications after pancreas transplantation

Boutros M, Al-Shaibi M, Chan G, Cantarovich M, et al. Clostridium Difficile Colitis: Increasing Incidence, Risk Factors, and Outcomes in Solid Organ Transplant Recipients. Transplantation 2012; 93:1051–1057. View Full Text | PubMed | CrossRef

de la Torre-Cisneros J, Farinas MC, Caston JJ, Aguado JM, et al. GESITRA-SEIMC/REIPI recommendations for the management of cytomegalovirus infection in solid-organ transplant patients. Enferm Infec Microbiol Clin 2011; 29:735–758.

Gala-Lopez BL, Senior PA, Koh A, Kashkoush SM, et al. Late Cytomegalovirus Transmission and Impact of T-Depletion in Clinical Islet Transplantation. Am J Transplant 2011; 11:2708–2714.

Grossi PA, Righi E, Dalla Gasperina D, Donati D, et al. Report of Four Simultaneous Pancreas-Kidney Transplants in HIV-Positive Recipients With Favorable Outcomes. Am J Transplant 2012; 12:1039–1045.

Matsumoto S, Takita M, Shimoda M, Itoh T, et al. Usefulness of the Secretory Unit of Islet Transplant Objects (SUITO) Index for Evaluation of Clinical Autologous Islet Transplantation. Transplant Proc 2011; 43:3246–3249. PubMed | CrossRef

Parsaik AK, Bhalla T, Dong M, Rostambeigi N, et al. Epidemiology of Cytomegalovirus Infection After Pancreas Transplantation. Transplantation 2011; 92:1044–1050. View Full Text | PubMed

Schnickel GT, Busuttil RW, Lipshutz GS. Improvement in Short-Term Pancreas Transplant Outcome by Targeted Antimicrobial Therapy and Refined Donor Selection. Am Surg 2011; 77:1407–1411. PubMed

Sher L, Jennings L, Rudich S, Alexopoulos SP, et al. Results of live donor liver transplantation in patients with hepatitic C virus infection: the HCV 3 trial experience. Clin Transplant 2012; 26:502–509. View Full Text | PubMed | CrossRef

Tavera M, Petroni J, Leon L, Minue E, et al. Reactive haemophagocytic syndrome associated with parvovirus B19 in a kidney-pancreas transplant patient. Nefrologia 2012; 32:125–126. PubMed

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Acute and chronic pancreatitis

Adrych K, Stojek M, Smoczynski M, Sledzinski T, et al. Increased serum chemerin concentration in patients with chronic pancreatitis. Dig Liver Dis 2012; 44:393–397. PubMed | CrossRef

Alsfasser G, Schwandner F, Pertschy A, Hauenstein K, et al. Treatment of Necrotizing Pancreatitis: Redefining the Role of Surgery. World JSurg 2012; 36:1142–1147.

Arikawa S, Uchida M, Kunou Y, Kaida H, et al. Assessment of Chronic Pancreatitis Use of Whole Pancreas Perfusion With 256-Slice Computed Tomography. Pancreas 2012; 41:535–540. View Full Text | PubMed | CrossRef

Awla D, Abdulla A, Syk I, Jeppsson B, et al. Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis. J Leukoc Biol 2012; 91:711–719. PubMed | CrossRef

Babu BI, Genovese T, Mazzon E, Riccardi L, et al. Recombinant Human Activated Protein C (Xigris) Attenuates Murine Cerulein-Induced Acute Pancreatitis Via Regulation of Nuclear Factor kappa B and Apoptotic Pathways. Pancreas 2012; 41:619–628. View Full Text | PubMed | CrossRef

Bajpai M, Tyagi P, Maharshi S. Therapeutic plasma exchange in hyperlipidemic pancreatitis. Transfusion 2012; 52:929. View Full Text | PubMed | CrossRef

Bakker OJ, van Santvoort HC, van Brunschot S, Geskus RB, et al. Endoscopic Transgastric vs Surgical Necrosectomy for Infected Necrotizing Pancreatitis A Randomized Trial. JAMA-J Am Med Assoc 2012; 307:1053–1061. View Full Text | PubMed | CrossRef

Barreto SG, Saccone GTP. Pancreatic nociception - Revisiting the physiology and pathophysiology. Pancreatology 2012; 12:104–112. PubMed | CrossRef

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Bollen TL. Imaging of Acute Pancreatitis: Update of the Revised Atlanta Classification. Radiol Clin N Am 2012; 50:429.

Curth HM, Drebber U, Stippel D, Bangard C, et al. A peculiar case of autoimmune pancreatitis and sclerosing cholangitis. Endoscopy 2012; 44:E226–E227. PubMed | CrossRef

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Feurer ME, Adler DG. Post-ERCP pancreatitis: review of current preventive strategies. Curr Opin Gastroenterol 2012; 28:280–286. View Full Text | PubMed | CrossRef

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Hallman JL, Mori S, Sharp GC, Lu HM, et al. A Four-Dimensional Computed Tomography Analysis of Multiorgan Abdominal Motion. Int J Radiat Oncol Biol Phys 2012; 83:435–441. PubMed | CrossRef

Hawthorne WJ, Simond DM, Stokes R, Patel AT, et al. Pre-clinical model of composite foetal pig pancreas fragment/renal xenotransplantation to treat renal failure and diabetes. Xenotransplantation 2011; 18:390–399. PubMed | CrossRef

Hines OJ, Donald GW. Endoscopic Transgastric Necrosectomy for Infected Necrotizing Pancreatitis. JAMA-J Am Med Assoc 2012; 307:1084–1085. View Full Text | PubMed | CrossRef

Ji YF, Zhang XM, Li XH, Jing ZL, et al. Gallbladder Patterns in Acute Pancreatitis: An MRI Study. Acad Radiol 2012; 19:571–578. PubMed

Jin H, Yu J, Wang WX, Chen C, et al. Serum Gc-globulin levels are reduced in patients with severe acute pancreatitis. Eur J Gastroenterol Hepatol 2012; 24:501–505. View Full Text | PubMed | CrossRef

Jurgensen C, Neser F, Boese-Landgraf J, Schuppan D, et al. Endoscopic ultrasound-guided endoscopic necrosectomy of the pancreas: is irrigation necessary? Surg Endosc 2012; 26:1359–1363.

Ke L, Ni HB, Tong ZH, Li WQ, et al. D-dimer as a marker of severity in patients with severe acute pancreatitis. J Hepato-Biliary-Pancreat Sci 2012; 19:259–265.

Kim JH, Kim MH, Byun JH, Lee SS, et al. Diagnostic Strategy for Differentiating Autoimmune Pancreatitis From Pancreatic Cancer Is an Endoscopic Retrograde Pancreatography Essential? Pancreas 2012; 41:639–647.

Kim KO, Kim TN. Acute Pancreatic Pseudocyst Incidence, Risk Factors, and Clinical Outcomes. Pancreas 2012; 41:577–581. View Full Text | PubMed | CrossRef

Knezevich E, Crnic T, Kershaw S, Drincic A. Liraglutide-associated acute pancreatitis. Am J Health-Syst Pharm 2012; 69:386–389. View Full Text | PubMed | CrossRef

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Li J, Zhao CC, Wang XM, Chen JH, et al. Hepatobiliary and Pancreatic: Autoimmune cholangitis, pancreatitis and sialadenitis. J Gastroenterol Hepatol 2012; 27:988. View Full Text | PubMed | CrossRef

Li QR, Wang CY, Zhang Q, Tang C, et al. The Role of Sphingosine Kinase 1 in Patients With Severe Acute Pancreatitis. Ann Surg 2012; 255:954–962. View Full Text | PubMed | CrossRef

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Perez-Johnston R, Sainani NI, Sahani DV. Imaging of Chronic Pancreatitis (Including Groove and Autoimmune Pancreatitis). Radiol Clin N Am 2012; 50:447.

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Rana SS, Bhasin DK, Rao C, Nada R, et al. Autoimmune pancreatitis presenting with gastric outlet obstruction. Gastrointest Endosc 2012; 75:1122–1123. PubMed | CrossRef

Rao AS, Le Roy AJ, Bonin EA, Sweetser SR, et al. Novel technique for placement of overlapping self-expandable metal stents to close a massive pancreatitis-induced duodenal fistula. Endoscopy 2012; 44:E163–E164. PubMed | CrossRef

Sambataro F, Pennuto M. Cell-autonomous and non-cell-autonomous toxicity in polyglutamine diseases. Prog Neurobiol 2012; 97:152–172. View Full Text | PubMed | CrossRef

Sasiwimonphan K, Gorman B, Kawashima A, Chari ST, et al. Renal involvement in patients with autoimmune pancreatitis: Ultrasound findings. Eur J Radiol 2012; 81:807–810. PubMed | CrossRef

Seven G, Schreiner MA, Ross AS, Lin OS, et al. Long-term outcomes associated with pancreatic extracorporeal shock wave lithotripsy for chronic calcific pancreatitis. Gastrointest Endosc 2012; 75:997–1004. PubMed | CrossRef

Shelton E, Froomes P, Fink MA. Gastrointestinal: Balloon pancreatitis. J Gastroenterol Hepatol 2012; 27:986. View Full Text | PubMed | CrossRef

Shen HN, Lu CL, Li CY. Effect of Diabetes on Severity and Hospital Mortality in Patients With Acute Pancreatitis A national population-based study. Diabetes Care 2012; 35:1061–1066. View Full Text | PubMed | CrossRef

Stevens T, Berk MP, Lopez R, Chung YM, et al. Lipidomic Profiling of Serum and Pancreatic Fluid in Chronic Pancreatitis. Pancreas 2012; 41:518–522. View Full Text | PubMed | CrossRef

Su MS, Lin MH, Zhao QH, Liu ZW, et al. Clinical study of distribution and drug resistance of pathogens in patients with severe acute pancreatitis. Chin Med J 2012; 125:1772–1776. View Full Text | PubMed

Sultan M, Werlin S, Venkatasubramani N. Genetic Prevalence and Characteristics in Children With Recurrent Pancreatitis. J Pediatr Gastroenterol Nutr 2012; 54:645–650. View Full Text | PubMed | CrossRef

Tabata T, Kamisawa T, Takuma K, Hara S, et al. Differences between diffuse and focal autoimmune pancreatitis. World J Gastroenterol 2012; 18:2099–2104. PubMed | CrossRef

Takuma K, Kamisawa T, Gopalakrishna R, Hara S, et al. Strategy to differentiate autoimmune pancreatitis from pancreas cancer. World J Gastroenterol 2012; 18:1015–1020. PubMed | CrossRef

Ting TW, Lee JH. Acute pancreatitis after propofol infusion in a teenage patient. Anaesth Intensive Care 2012; 40:561–562. PubMed

Tracy TF. Editorial: Acute pancreatitis and neutrophil gelatinase MMP9: don't get me started!. J Leukoc Biol 2012; 91:682–684. PubMed | CrossRef

Tu XH, Song JX, Xue XJ, Guo XW, et al. Role of bone marrow-derived mesenchymal stem cells in a rat model of severe acute pancreatitis. World J Gastroenterol 2012; 18:2270–2279. PubMed | CrossRef

van Baal MC, Besselink MG, Bakker OJ, van Santvoort HC, et al. Timing of Cholecystectomy After Mild Biliary Pancreatitis A Systematic Review. Ann Surg 2012; 255:860–866. View Full Text | PubMed | CrossRef

Wang SQ, Feng QX, Li SJ, Xu B, et al. The Day When Infection Is Confirmed Is a Better Time Point for Mortality Prediction in Patients With Severe Acute Pancreatitis. Pancreas 2012; 41:605–610. View Full Text | PubMed | CrossRef

Weng TI, Wu HY, Chen BL, Liu SH. Honokiol attenuates the severity of acute pancreatitis and associated lung injury via acceleration of acinar cell apoptosis. Shock 2012; 37:478–484. View Full Text | PubMed | CrossRef

Will U, Wanzar I, Meyer F. Endoscopic Necrosectomy-a Feasible and Safe Alternative Treatment Option for Infected Pancreatic Necroses in Severe Acute Pancreatitis Preliminary Results of 18 Patients in an Ongoing Single-Center Prospective Observational Study. Pancreas 2012; 41: 652–655.

Xia XM, Li BK, Xing SM, Ruan HL. Emodin promoted pancreatic claudin-5 and occludin expression in experimental acute pancreatitis rats. World J Gastroenterol 2012; 18:2132–2139. PubMed | CrossRef

Yu YH, Sohn JH, Kim TY, Jeong JY, et al. Hepatic artery pseudoaneurysm caused by acute idiopathic pancreatitis. World J Gastroenterol 2012; 18:2291–2294. PubMed | CrossRef

Zechner D, Spitzner M, Bobrowski A, Knapp N, et al. Diabetes aggravates acute pancreatitis and inhibits pancreas regeneration in mice. Diabetologia 2012; 55:1526–1534. View Full Text | PubMed | CrossRef

Zhu HH, Jiang LL. Serum inter-cellular adhesion molecule 1 is an early marker of diagnosis and prediction of severe acute pancreatitis. World J Gastroenterol 2012; 18:2554–2560. PubMed | CrossRef

Zhu RR, Wei SD, Wu CX, Li SW, et al. Utility of Clot Formation and Lysis Assay to Monitor Global Coagulation State of Patients with Severe Acute Pancreatitis. Dig Dis Sci 2012; 57:1399–1403. View Full Text | PubMed | CrossRef

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Pancreato - biliary neoplasms

Adamczyk B, Tharmalingam T, Rudd PM. Glycans as cancer biomarkers. Biochim Biophys Acta-Gen Subj 2012; 1820:1347–1353. PubMed | CrossRef

Ali S, Banerjee S, Logna F, Bao B, et al. Inactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer. J Cell Physiol 2012; 227:3373–3380. PubMed | CrossRef

Bar F, Sina C, Schmidt KJ, Vogt FM, et al. CEUS as a Tool to Uncover an Unusual Cause of Obstructive Jaundice. Z Gastroent 2012; 50:449–452.

Bonnet S, Berger A, Hentati N, Abid B, et al. High Tie Versus Low Tie Vascular Ligation of the Inferior Mesenteric Artery in Colorectal Cancer Surgery: Impact on the Gain in Colon Length and Implications on the Feasibility of Anastomoses. Dis Colon Rectum 2012; 55:515–521.

Boyd CA, Benarroch-Gampel J, Kilic G, Kruse EJ, et al. Pancreatic Neoplasms in Pregnancy: Diagnosis, Complications, and Management. J Gastrointest Surg 2012; 16:1064–1071. PubMed | CrossRef

Boyd CA, Benarroch-Gampel J, Sheffield KM, Cooksley CD, et al. 415 Patients with Adenosquamous Carcinoma of the Pancreas: A Population-Based Analysis of Prognosis and Survival. J Surg Res 2012; 174:12–19. PubMed

Braat H, Bruno M, Kuipers EJ, Peppelenbosch MP. Pancreatic cancer: Promise for personalised medicine? Cancer Lett 2012; 318:1–8.

Brenner R, Metens T, Bali M, Demetter P, et al. Pancreatic neuroendocrine tumor: Added value of fusion of T2-weighted imaging and high b-value diffusion-weighted imaging for tumor detection. Eur J Radiol 2012; 81:E746–E749. PubMed | CrossRef

Chen Y, Shi M, Yu GZ, Qin XR, et al. Interleukin-8, a promising predictor for prognosis of pancreatic cancer. World J Gastroenterol 2012; 18:1123–1129.

De Angelis P, Foschia F, Romeo E, Caldaro T, et al. Role of endoscopic retrograde cholangiopancreatography in diagnosis and management of congenital choledochal cysts: 28 pediatric cases. J Pediatr Surg 2012; 47:885–888.

De Rango P, Parlani G, Silvestri V. Pseudoaneurysm in chronic pancreatitis. Can Med Assoc J 2012; 184:433.

Dewhurst CE, Mortele KJ. Cystic Tumors of the Pancreas: Imaging and Management. Radiol Clin N Am 2012; 50:467.

Di Marzo V. De-liver-ance'' From CB1: A Way to Counteract Insulin Resistance? Gastroenterology 2012; 142:1063–1066.

Dutta SK, Girotra M, Singla M, Dutta A, et al. Serum HSP70 A Novel Biomarker for Early Detection of Pancreatic Cancer. Pancreas 2012; 41:530–534.

Edelman A, Saussereau E. Cystic Fibrosis and other channelopathies. Arch Pediatr 2012; 19:S13–S16.

Eheman C, Henley SJ, Ballard-Barbash R, Jacobs EJ, et al. Annual Report to the Nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity. Cancer 2012; 118:2338–2366.

Fiebrich HB, van Asselt SJ, Brouwers AH, van Dullemen HM, et al. Tailored imaging of islet cell tumors of the pancreas amidst increasing options. Crit Rev Oncol/Hematol 2012; 82:213–226.

Fuks D, Sabbagh C, Yzet T, Delcenserie R, et al. Cirrhosis Should not be Considered as an Absolute Contraindication for Pancreatoduodenectomy. Hepato-Gastroenterol 2012; 59:881–883.

Gardini A, Morgagni P, Milandri C, Riccobon A, et al. Pancreatic Resection for Metastases from Renal Cancer: Long Term Outcome after Surgery and Immunotherapy Approach - Single Center Experience. Hepato-Gastroenterol 2012; 59:687–690.

Gheonea DI, Ciurea ME, Saftoiu A, Ioana M. Quantitative RT-PCR Analysis of MMR Genes on EUS-Guided FNA Samples From Focal Pancreatic Lesions. Hepato-Gastroenterol 2012; 59:916–920.

Giudici F, Nesi G, Brandi ML, Tonelli F. Surgical Management of Insulinomas in Multiple Endocrine Neoplasia Type 1. Pancreas 2012; 41:547–553.

Glick RD, Pashankar FD, Pappo A, La Quaglia MP. Management of Pancreatoblastoma in Children and Young Adults. J Pediatr Hematol Oncol 2012; 34:S47–S50.

Goggins M. GLP-1 Receptor Agonist Effects on Normal and Neoplastic Pancreata. Diabetes 2012; 61:989–990.

Goyal K, Einstein D, Ibarra RA, Yao M, et al. Stereotactic Body Radiation Therapy for Nonresectable Tumors of the Pancreas. J Surg Res 2012; 174:319–325.

Grippo PJ, Sandgren EP. Acinar-to-ductal metaplasia accompanies c-myc-induced exocrine pancreatic cancer progression in transgenic rodents. Int J Cancer 2012; 131:1243–1248.

Grote VA, Kaaks R, Nieters A, Tjonneland A, et al. Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort. Br J Cancer 2012; 106:1866–1874.

Grote VA, Rohrmann S, Dossus L, Nieters A, et al. The association of circulating adiponectin levels with pancreatic cancer risk: A study within the prospective EPIC cohort. Int J Cancer 2012; 130:2428–2437.

Gwon DI, Ko GY, Sung KB, Yoon HK, et al. Clinical outcomes after percutaneous biliary interventions in patients with malignant biliary obstruction caused by metastatic gastric cancer. Acta Radiol 2012; 53:422–429.

Hamada S, Masamune A, Takikawa T, Suzuki N, et al. Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells. Biochem Biophys Res Commun 2012; 421:349–354.

Hashimoto Y, Traverso LW. After Distal Pancreatectomy Pancreatic Leakage from the Stump of the Pancreas May Be Due to Drain Failure or Pancreatic Ductal Back Pressure. J Gastrointest Surg 2012; 16:993–1003.

Hillner BE, Siegel BA, Hanna L, Shields AF, et al. Impact of F-18-FDG PET Used After Initial Treatment of Cancer: Comparison of the National Oncologic PET Registry 2006 and 2009 Cohorts. J Nucl Med 2012; 53:831–837.

Hirota M, Shimosegawa T, Masamune A, Kikuta K, et al. The sixth nationwide epidemiological survey of chronic pancreatitis in Japan. Pancreatology 2012; 12:79–84.

Holalkere NS, Soto J. Imaging of Miscellaneous Pancreatic Pathology (Trauma, Transplant, Infections, and Deposition). Radiol Clin N Am 2012; 50:515.

Ishii H, Taniguchi H, Shiozaki A, Kuriu Y, et al. Use of Multidetector-Row Computed Tomography to Evaluate Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: Influence on Surgical Decision-Making. Hepato-Gastroenterol 2012; 59:884–888.

Jokoji R, Tsuji H, Tsujimoto M, Shinno N, et al. Intraductal tubulopapillary neoplasm of pancreas with stromal osseous and cartilaginous metaplasia; a case report. Pathol Int 2012; 62:339–343.

Jurgensen C, Neser F, Boese-Landgraf J, Schuppan D, et al. Endoscopic ultrasound-guided endoscopic necrosectomy of the pancreas: is irrigation necessary? Surg Endosc 2012; 26:1359–1363.

Kalaitzakis E, Webster GJ. Endoscopic diagnosis of biliary tract disease. Curr Opin Gastroenterol 2012; 28:273–279.

Katanuma A, Maguchi H, Hashigo S, Kaneko M, et al. Tumor seeding after endoscopic ultrasound-guided fine-needle aspiration of cancer in the body of the pancreas. Endoscopy 2012; 44:E160–E161.

Kelly PJ, Spence R, Dasari BV, Burt AD, et al. Primary hepatocellular carcinoma of the pancreas: a case report and review of the heterogeneous group of pancreatic hepatoid carcinomas. Histopathology 2012; 60:1012–1015.

Kim JH, Kim MH, Byun JH, Lee SS, et al. Diagnostic Strategy for Differentiating Autoimmune Pancreatitis From Pancreatic Cancer Is an Endoscopic Retrograde Pancreatography Essential? Pancreas 2012; 41:639–647.

Kim KO, Kim TN. Acute Pancreatic Pseudocyst Incidence, Risk Factors, and Clinical Outcomes. Pancreas 2012; 41:577–581.

Kisiel JB, Yab TC, Taylor WR, Chari ST, et al. Stool DNA testing for the detection of pancreatic cancer Assessment of Methylation Marker Candidates. Cancer 2012; 118:2623–2631.

Klibansky DA, Reid-Lombardo KM, Gordon SR, Gardner TB. The Clinical Relevance of the Increasing Incidence of Intraductal Papillary Mucinous Neoplasm. Clin Gastroenterol Hepatol 2012; 10:555–558.

Kobayashi T, Sato Y, Hirukawa H, Soeno M, et al. Total Pancreatectomy Combined with Partial Pancreas Autotransplantation for Recurrent Pancreatic Cancer: A Case Report. Transplant Proc 2012; 44:1176–1179.

Korompay A, Borka K, Lotz G, Somoracz A, et al. Tricellulin expression in normal and neoplastic human pancreas. Histopathology 2012; 60:E76–E86.

Lee JH, Kim JK, Kim TH, Park MS, et al. MRI features of serous oligocystic adenoma of the pancreas: differentiation from mucinous cystic neoplasm of the pancreas. Br J Radiol 2012; 85:571–576.

Lee LS, Conwell DL. Update on Advanced Endoscopic Techniques for the Pancreas: Endoscopic Retrograde Cholangiopancreatography, Drainage and Biopsy, and Endoscopic Ultrasound. Radiol Clin N Am 2012; 50:547.

Levy MJ, Oberg TN, Campion MB, Clayton AC, et al. Comparison of Methods to Detect Neoplasia in Patients Undergoing Endoscopic Ultrasound-Guided Fine-Needle Aspiration. Gastroenterology 2012; 142:1112.

Li JX, Wu H, Huang JW, Prasoon P, et al. Synchronous intraoperative radiofrequency ablation for multiple liver metastasis and resection of giant solid pseudopapillary tumors of the pancreas. Chin Med J 2012; 125:1661–1663.

Li X, Lee SO, Safe S. Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3 '-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells. Biochem Pharmacol 2012; 83:1445–1455.

Li XJ, Guo QH, Wang X, Xue B, et al. LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling. Chin Med J 2012; 125:1695–1702.

Li XQ, Ma QY, Xu QH, Liu H, et al. SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway. Cancer Lett 2012; 322:169–176.

Lim JU, Joo KR, Cha JM, Shin HP, et al. Early Use of Needle-Knife Fistulotomy Is Safe in Situations Where Difficult Biliary Cannulation Is Expected. Dig Dis Sci 2012; 57:1384–1390.

Linhares MM, Beron RI, Gonzalez AM, Tarazona C, et al. Duodenum-Stomach Anastomosis: a New Technique for Exocrine Drainage in Pancreas Transplantation. J Gastrointest Surg 2012; 16:1072–1075.

Liu HY, Shi JH, Wang HLL, Zhang J, et al. Expression of von Hippel-Lindau Gene Product (pVHL) and S100P in Cystic Neoplasms of the Pancreas - with an Implication for Their Roles in Tumorigenesis. Ann Clin Lab Sci 2012; 42:109–117.

Malleo G, Bassi C, Rossini R, Manfredi R, et al. Growth pattern of serous cystic neoplasms of the pancreas: observational study with long-term magnetic resonance surveillance and recommendations for treatment. Gut 2012; 61: 746–751.

Marangos IP, Buanes T, Rosok BI, Kazaryan AM, et al. Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival. Surgery 2012; 151:717–723.

Matsuyama M, Kondo F, Ishihara T, Yamaguchi T, et al. Evaluation of pancreatic intraepithelial neoplasia and mucin expression in normal pancreata. J Hepato-Biliary-Pancreat Sci 2012; 19:242–248.

Mayo SC, Nathan H, Cameron JL, Olino K, et al. Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intent. Cancer 2012; 118:2674–2681.

Megibow AJ. Unusual Solid Pancreatic Tumors. Radiol Clin N Am 2012; 50:499.

Menge BA, Breuer TGK, Ritter PR, Uhl W, et al. Long-term recovery of beta-cell function after partial pancreatectomy in humans. Metab-Clin Exp 2012; 61:620–624.

Merilainen S, Makela J, Koivukangas V, Jensen HA, et al. Intestinal Bacterial Translocation and Tight Junction Structure in Acute Porcine Pancreatitis. Hepato-Gastroenterol 2012; 59:599–606.

Min SH, Kim HY, Kim SH, Jung SE, et al. Gastric adenomyoma mimicking gastric duplication cyst in a 5-year-old girl. J Pediatr Surg 2012; 47:1019–1022.

Mizuno S, Isaji S, Ohsawa I, Kishiwada M, et al. Pancreaticoduodenectomy with resection of the splenic artery and splenectomy for pancreatic double cancers after total gastrectomy. Preservation of the pancreatic function via the blood supply from the posterior epiploic artery: report of a case. Surg Today 2012; 42:482–488.

Moon JH, Choi HJ, Koo HC, Han SH, et al. Feasibility of placing a modified fully covered self-expandable metal stent above the papilla to minimize stent-induced bile duct injury in patients with refractory benign biliary strictures (with videos). Gastrointest Endosc 2012; 75:1080–1085.

Naitoh I, Nakazawa T, Hayashi K, Okumura F, et al. Clinical differences between mass-forming autoimmune pancreatitis and pancreatic cancer. Scand J Gastroenterol 2012; 47:607–613.

Nimura Y, Nagino M, Takao S, Takada T, et al. Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adenocarcinoma of the head of the pancreas Long-term results of a Japanese multicenter randomized controlled trial. J Hepato-Biliary-Pancreat Sci 2012; 19:230–241.

Okamura Y, Fujii T, Kanzaki A, Yamada S, et al. Clinicopathologic Assessment of Pancreatic Ductal Carcinoma Located at the Head of the Pancreas, in Relation to Embryonic Development. Pancreas 2012; 41:582–588.

Padilla-Thornton AE, Willmann JK, Jeffrey RB. Adenocarcinoma of the uncinate process of the pancreas: MDCT patterns of local invasion and clinical features at presentation. Eur Radiol 2012; 22:1067–1074.

Panarelli NC, Park KJ, Hruban RH, Klimstra DS. Microcystic Serous Cystadenoma of the Pancreas With Subtotal Cystic Degeneration: Another Neoplastic Mimic of Pancreatic Pseudocyst. Am J Surg Pathol 2012; 36:726–731.

Peng CH, Shen BY, Deng XX, Zhan Q, et al. Early Experience for the Robotic Duodenum-preserving Pancreatic Head Resection. World JSurg 2012; 36:1136–1141.

Puri A, Acharya H, Tyagi S, Curian S, et al. Pseudoaneurysm of the radial branch of the splenic artery with pancreatic pseudocyst in a child with recurrent acute pancreatitis: treatment with endovascular stent graft and cystogastrostomy. J Pediatr Surg 2012; 47:1012–1015.

Rebours V, Couvelard A, Peyroux JL, Sauvanet A, et al. Familial intraductal papillary mucinous neoplasms of the pancreas. Dig Liver Dis 2012; 44:442–446.

Rindi G, Falconi M, Klersy C, Albarello L, et al. TNM Staging of Neoplasms of the Endocrine Pancreas: Results From a Large International Cohort Study. J Natl Cancer Inst 2012; 104:764–777.

Roland CL, Bian AH, Mansour JC, Yopp AC, et al. Survival impact of malignant pancreatic neuroendocrine and islet cell neoplasm phenotypes. J Surg Oncol 2012; 105:595–600.

Rust E, Hubele F, Marzano E, Goichot B, et al. Nuclear medicine imaging of gastro-entero-pancreatic neuroendocrine tumors. The key role of cellular differentiation and tumor grade: from theory to clinical practice. Cancer Imaging 2012; 12:173–184.

Sadeghi N, Abbruzzese JL, Yeung SCJ, Hassan M, et al. Metformin Use Is Associated with Better Survival of Diabetic Patients with Pancreatic Cancer. Clin Cancer Res 2012; 18:2905–2912.

Schimmack S, Lawrence B, Svejda B, Alaimo D, et al. The clinical implications and biologic relevance of neurofilament expression in gastroenteropancreatic neuroendocrine neoplasms. Cancer 2012; 118:2763–2775.

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Factors affecting pancreatic development and functions

Abdulla A, Awla D, Hartman H, Weiber H, et al. Platelets regulate P-selectin expression and leukocyte rolling in inflamed venules of the pancreas. Eur J Pharmacol 2012; 682:153–160.

Afelik S, Qu XL, Hasrouni E, Bukys MA, et al. Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells. Development 2012; 139:1744–1753.

Alexander LF. Congenital Pancreatic Anomalies, Variants, and Conditions. Radiol Clin N Am 2012; 50:487.

Andersen DK. The practical importance of recognizing pancreatogenic or type 3c diabetes. Diabetes-Metab Res Rev 2012; 28:326–328.

Andralojc K, Srinivas M, Brom M, Joosten L, et al. Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis. Diabetologia 2012; 55:1247–1257.

Bajpai M, Tyagi P, Maharshi S. Therapeutic plasma exchange in hyperlipidemic pancreatitis. Transfusion 2012; 52:929.

Basford CL, Prentice KJ, Hardy AB, Sarangi F, et al. The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells. Diabetologia 2012; 55:358–371.

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