Complementary and alternative medicine has become immensely popular. This review summarizes the recent literature on complementary and alternative medicine for rheumatic conditions. Research has emerged in the following areas: acupuncture, herbal remedies, homeopathy, magnetic fields, massage therapy, spiritual healing, and supplements. Positive evidence was found in relation to glucosamine, chondroitin, some herbal remedies, and acupuncture. Generally speaking, complementary and alternative medicine is grossly underresearched. Because of the popularity of complementary and alternative medicine, adequately defining risk-benefit relationships is an urgent matter.