Skip Navigation LinksHome > January 1995 - Volume 8 - Issue 1 > Genetics of psychosis
Current Opinion in Psychiatry:
Schizophrenia

Genetics of psychosis

Sasaki, Tsukasa; Kennedy, James L.

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Abstract

Two advances have been achieved in molecular genetic approches to schizophrenia.The first is progress in the search for linkage across all the human chromosomes. The second advance is the discovery of a new kind of DNA mutation, unstable trinucleotide repeats, that is responsible for several neuropsychiatric disorders. Significant evidence suggests that these unstable genes may also be related to psychotic diseases such as schizophrenia. A number of candidate loci, including neurodevelopmental genes, have been tested and several regions appear promising.

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