The role of hydration in vocal fold physiologySivasankar, Mahalakshmia; Leydon, CiarabCurrent Opinion in Otolaryngology & Head and Neck Surgery: June 2010 - Volume 18 - Issue 3 - p 171–175 doi: 10.1097/MOO.0b013e3283393784 Speech therapy and rehabilitation: Edited by Bernice K. Klaben Abstract Author Information Purpose of review Increased vocal fold hydration is a popular target in the prevention and management of voice disorders. Current intervention strategies focus on enhancing both systemic (internal) and superficial (surface) hydration. We review relevant bench and human research on the role of hydration in vocal fold physiology. Recent findings Bench and human studies provide converging evidence that systemic and superficial dehydration are detrimental to vocal fold physiology. Dehydration challenges increase the viscous properties of excised vocal fold tissue. Systemic, superficial, and combined drying challenges increase aerodynamic and acoustic measures of voice production in speakers. Emerging theoretical and clinical data suggest that increasing both systemic and superficial hydration levels may benefit voice production; however, robust evidence for positive outcomes of hydration treatments is lacking. Summary Increased systemic and superficial vocal fold hydration as a component of vocal hygiene may improve overall health and efficiency of the vocal apparatus. However, continued exploration of biological mechanisms regulating vocal fold hydration is needed to optimize clinical hydration interventions. Specifically, the development of hydration treatments that maximize positive phonatory outcomes will necessitate understanding of the signaling pathways linking systemic and superficial hydration. aDepartment of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, Indiana bDepartment of Speech Communication Arts and Sciences, Brooklyn College of The City University of New York, New York, USA Correspondence to Mahalakshmi Sivasankar, Department of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, IN 47907, USA Tel: +1 765 496 6628; fax: +1 765 494 0771; e-mail: email@example.com © 2010 Lippincott Williams & Wilkins, Inc.