Skip Navigation LinksHome > October 2006 - Volume 14 - Issue 5 > Aquaporins and Meniere's disease
Current Opinion in Otolaryngology & Head & Neck Surgery:
doi: 10.1097/01.moo.0000244191.51560.22
Hearing science

Aquaporins and Meniere's disease

Ishiyama, Gaila; López, Ivan Ab; Ishiyama, Akirab

Collapse Box

Abstract

Purpose of review: Review of the role of aquaporins in inner ear homeostasis and potential role in the pathogenesis of Meniere's disease.

Recent findings: Recent findings include the immunolocalization of aquaporins in the inner ear of mouse, rat, and human to cell types that are likely to undergo high ionic perturbances (e.g. potassium flux) and to putative areas of endolymph resorption or cycling.

Summary: The expression of aquaporins and related proteins in the human cochlea and vestibular periphery resembles the distribution found in animal models, suggesting a critical role of aquaporins in inner ear water homeostasis and their potential role in the pathogenesis of Meniere's disease.

© 2006 Lippincott Williams & Wilkins, Inc.

Login

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.