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Age-related macular degeneration and depression: a review of recent research

Casten, Robin Ja; Rovner, Barry Wa; Tasman, Williamb

Current Opinion in Ophthalmology:
doi: 10.1097/
Retinal, vitreous and macular disorders


Purpose of review:The purpose of this review is to summarize current research findings regarding relationships between depression and age-related macular degeneration (AMD).

Recent findings:The current literature indicates that the prevalence of depression among patients with AMD is fairly high (approximately 30%) and that depression is a major cause of disability among patients with AMD, even when severity of vision loss is considered. Interventions to alleviate the emotional distress associated with vision loss are also discussed.

Summary:Several studies indicate that AMD is a risk factor for depression, and this has serious consequences for the quality of life among patients with AMD.

Author Information

aJefferson Medical College and bWills Eye Hospital, Philadelphia, Pennsylvania, USA

Correspondence to Robin Casten, Jefferson Hospital for Neuroscience, 900 Walnut Street, 8th floor, Philadelphia, PA 19107, USA

Tel: 215 503 1250; fax: 215 503 1992; e-mail:

© 2004 Lippincott Williams & Wilkins, Inc.