Skip Navigation LinksHome > October 2013 - Volume 25 - Issue 5 > Management of vaginal agenesis
Current Opinion in Obstetrics & Gynecology:
doi: 10.1097/GCO.0b013e328363d67f
ADOLESCENT AND PEDIATRIC GYNECOLOGY: Edited by Paula J. Adams Hillard

Management of vaginal agenesis

Edmonds, D. Keith

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Abstract

Purpose of review

Mayer–Rokitansky–Küster–Hauser syndrome is undergoing new research outcomes involving genetics and management.

Recent findings

Recent literature supports a polygenic multifactorial genetic basis for the syndrome. Management is now predominantly by vaginal dilators and nonsurgical, but holistic. The future of uterine transplantation is discussed.

Summary

New developments open new possibilities for understanding the genetic basis of the disease, and research in this area will continue. Management in terms of fertility may have an added dimension if uterine transplantation and successful pregnancy outcome can be proven.

© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

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