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Pregnancy and the kidney transplant recipient

Vijayan, Madhusudana; Pavlakis, Marthab

Current Opinion in Nephrology & Hypertension: November 2017 - Volume 26 - Issue 6 - p 494–500
doi: 10.1097/MNH.0000000000000363
DIALYSIS AND TRANSPLANTATION: Edited by J. Kevin Tucker and Anil Chandraker

Purpose of review: The current article reviews the available literature on the incidence, complications, outcomes, and management of pregnancies in kidney transplant recipients.

Recent findings: Pregnancy can be a reasonable option for women with a kidney transplant. More than 4700 successful pregnancies have been reported after kidney transplantation. New data have emerged regarding the risk of allograft dysfunction following pregnancy. There is a lack of consensus on the optimal time for conception, immunosuppressive targets, the safety of allograft biopsy, and infection surveillance. Successful pregnancies have recently been reported in ABO-incompatible transplant recipients and recipients of combined heart–kidney transplants.

Summary: The ideal contraceptive method, timing of conception, immunosuppressant protocol, infection surveillance, and the method of delivery should be individualized depending on the patient's age and medical conditions.

aRenal Division, Department of Medicine and Transplantation Research Center, Brigham and Women's Hospital

bRenal Division, Department of Medicine and Transplant Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Correspondence to Martha Pavlakis, Beth Israel Deaconess Medical Center, Harvard Medical School, 110 Francis Street, Boston, MA 02115, USA. Tel: +1 617 632 9700; e-mail: mpavlaki@bidmc.harvard.edu

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