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Omega-3 fatty acids and prevention of arrhythmias

Leaf, Alexander

doi: 10.1097/MOL.0b013e328012d61b
Nutrition and metabolism

Purpose of review There is now a considerable factual basis from laboratory and clinical trials that omega-3 fatty acids of fish oil will prevent fatal arrhythmias in animals and humans and this is the focus of the review.

Recent findings Several recent trials in humans have strengthened the evidence that omega-3 fatty acids may prevent arrhythmias although this has not been a uniform finding.

Summary Since there are at present some 400 000 deaths annually in the US alone and millions more worldwide, what has been learned about the antiarrhythmic actions of omega-3 fatty acids has considerable potential public-health benefit.

Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

Correspondence to Alexander Leaf, 149, Room 4001, 13th Street, Charlestown, MA 02129, USA Tel: +1 617 726 5908; fax: +1 617 726 6144; e-mail: aleaf@partners.org

© 2007 Lippincott Williams & Wilkins, Inc.