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Omega-3 fatty acids and prevention of arrhythmias

Leaf, Alexander

doi: 10.1097/MOL.0b013e328012d61b
Nutrition and metabolism

Purpose of review: There is now a considerable factual basis from laboratory and clinical trials that omega-3 fatty acids of fish oil will prevent fatal arrhythmias in animals and humans and this is the focus of the review.

Recent findings: Several recent trials in humans have strengthened the evidence that omega-3 fatty acids may prevent arrhythmias although this has not been a uniform finding.

Summary: Since there are at present some 400 000 deaths annually in the US alone and millions more worldwide, what has been learned about the antiarrhythmic actions of omega-3 fatty acids has considerable potential public-health benefit.

Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA

Correspondence to Alexander Leaf, 149, Room 4001, 13th Street, Charlestown, MA 02129, USA Tel: +1 617 726 5908; fax: +1 617 726 6144; e-mail: aleaf@partners.org

© 2007 Lippincott Williams & Wilkins, Inc.