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Current Opinion in Infectious Diseases:
doi: 10.1097/QCO.0b013e328334de21
Sexually transmitted diseases and urinary tract infections Edited: by Anton L. Pozniak

Current concepts in managing pelvic inflammatory disease

Judlin, Philippe

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Abstract

Purpose of review: The management of pelvic inflammatory disease (PID) has significantly changed during the last two decades. Moreover, some recent bacterial findings have led to recent changes in this management.

Recent findings: Most cases of PID are mild-to-moderate uncomplicated forms that can be treated as outpatients. Apart from Chlamydia trachomatis and Neisseria gonorrhoeae, other pathogens such as Mycoplasma genitalium and bacterial vaginosis (BV)-associated bacteria are playing a significant role in PID and thus must be reckoned with. Moreover, gonococci have increasingly become resistant to the majority of antibiotics. This has led to a universal recommendation to treat N. gonorrhoeae infections with ceftriaxone. A few recent clinical trials have shown that quinolones and azithromycin (with metronidazole) are the best therapeutic options to treat uncomplicated PID.

Summary: The management of PID nowadays must take into account the role of pathogens such as M. genitalium, BV-associated bacteria and multiresistant gonococci.

© 2010 Lippincott Williams & Wilkins, Inc.

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