Current Opinion in HIV & AIDS:
doi: 10.1097/COH.0b013e32830b5d4c
Microbicides: Edited by John Kaldor and Melissa Robbiani

Editorial comment

Robbiani, Melissa

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Center for Biomedical Research, HIV and AIDS Program, Population Council, New York, New York, USA

Correspondence to Melissa Robbiani, Center for Biomedical Research, HIV and AIDS Program, Population Council, 1230 York Avenue, New York, NY 10065, USA Tel: +1 212 327 7794; fax: +1 212 327 7764; e-mail: mrobbiani@popcouncil.org

This special edition of Current Opinion in HIV and AIDS provides an overview of the recent salient events in microbicides research. While there is little published on product development per se, we have included an introductory review of the issues that need to be considered in microbicide product development. We have endeavored to encompass the latest findings on the basic biology of infection and the role of the immune system, the pros and cons of animal models for preclinical testing, potential new microbicides and options on how to formulate them, what we have learned from the clinical trials on efficacy, acceptability, adherence, and trial design, potential for rectal microbicides, and how we can utilize mathematical modeling to advance microbicides research.

© 2008 Lippincott Williams & Wilkins, Inc.

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