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Current Opinion in Gastroenterology:
doi: 10.1097/MOG.0b013e32835a4c77
CURRENT WORLD LITERATURE: Bibliography

Current World Literature

Free Access

This bibliography is compiled by clinicians from the relevant journals scanned by this publication. It is based on the literature regularly pulled into our database from OvidSP (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

▪ Papers considered by the reviewers to be of special interest

▪▪ Papers considered by the reviewers to be of outstanding interest

The number in square brackets following a selected paper, e.g. [7], refers to its number in the annotated references of the corresponding review.

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Gastrointestinal infections
Prevention of catheter-related blood stream infections in children with intestinal failure

Review: (pp. 1–6)

Cavanagh HMA, Mahony TJ, Vanniasinkam T. Genetic characterization of equine adenovirus type 1. Vet Microbiol 2012; 155:33–37. PubMed | CrossRef

▪. Cober MP, Kovacevich DS, Teitelbaum DH. Ethanol-lock therapy for the prevention of central venous access device infections in pediatric patients with intestinal failure. JPEN J Parenter Enteral Nutr 2011; 35:67–73. [20]

▪▪. Dumichen MJ, Seeger K, Lode HN, et al. Randomized controlled trial of taurolidine citrate versus heparin as catheter lock solution in paediatric patients with haematological malignancies. J Hosp Infect 2012; 80:304–309. [44]

▪. Gillanders L, Angstmann K, Ball P, et al. A prospective study of catheter-related complications in HPN patients. Clin Nutr 2012; 31:30–34. [38]

▪▪. O'Grady NP, Alexander M, Burns LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control 39(4 Suppl 1)2011:S1–S34. [25]

▪▪. Oliveira C, Nasr A, Brindle M, Wales PW. Ethanol locks to prevent catheter-related bloodstream infections in parenteral nutrition: a meta-analysis. Pediatrics 2012; 129:318–329. [51]

▪▪. Secola R, Lewis MA, Pike N, et al. ‘Targeting to zero’ in pediatric oncology: a review of central venous catheter-related bloodstream infections. J Pediatr Oncol Nurs 2012; 29:14–27. [27]

Viswanathan R, Singh AK, Ghosh C, Dasgupta S, et al. Profile of Neonatal Septicaemia at a District-level Sick Newborn Care Unit. J Heatlh Popul Nutr 2012; 30:41–48.

▪. Wales PW, Kosar C, Carricato M, et al. Ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients with intestinal failure: preliminary experience. J Pediatr Surg 2011; 46:951–956. [23]

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Eosinophils in infection and intestinal immunity

Review: (pp. 7–14)

Annunziata ML, Caviglia R, Papparella LG, Cicala M. Upper Gastrointestinal Involvement of Crohn's Disease: A Prospective Study on the Role of Upper Endoscopy in the Diagnostic Work-Up. Dig Dis Sci 2012; 57:1618–1623. View Full Text | PubMed | CrossRef

Baker TW, Quinn JM. Aspirin therapy in aspirin-exacerbated respiratory disease: A risk-benefit analysis for the practicing allergist. Allergy Asthma Proc 2011; 32:335–340.

Benavides JA, Huchard E, Pettorelli N, King AJ, et al. From parasite encounter to infection: Multiple-scale drivers of parasite richness in a wild social primate population. Am J Phys Anthropol 2012; 147:52–63. PubMed | CrossRef

Bertolazzi S, Lanzarotto F, Zanini B, Ricci C, et al. Bio-physical characteristics of gastrointestinal mucosa of celiac patients: comparison with control subjects and effect of gluten free diet- - art. no. 119. BMC Gastroenterol 2011; 11:7.

Bowcutt R, Bell LV, Little M, Wilson J, et al. Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris. Parasite Immunol 2011; 33:411–420. View Full Text | PubMed | CrossRef

Chapman CA, Bowman DD, Ghai RR, Gogarten JF, et al. Protozoan parasites in group-living primates: testing the biological island hypothesis. Am J Primatol 2012; 74:510–517. PubMed | CrossRef

Cheek JE, Hennessy TW, Redd JT, Cobb N, et al. Epidemic Assistance From the Centers for Disease Control and Prevention Involving American Indians and Alaska Natives, 1946–2005. Am J Epidemiol 2011; 174:S89–S96. View Full Text | PubMed | CrossRef

Chow J, Tang HQ, Mazmanian SK. Pathobionts of the gastrointestinal microbiota and inflammatory disease. Curr Opin Immunol 2011; 23:473–480. PubMed | CrossRef

Du Pont HL. Gastrointestinal infections and the development of irritable bowel syndrome. Curr Opin Infect Dis 2011; 24:503–508.

Fairley RA, Pesavento PA, Clark RG. Listeria monocytogenes Infection of the Alimentary Tract (Enteric Listeriosis) of Sheep in New Zealand. J Comp Pathol 2012; 146:308–313. PubMed | CrossRef

Foster N, Elsheikha HM. The immune response to parasitic helminths of veterinary importance and its potential manipulation for future vaccine control strategies. Parasitol Res 2012; 110:1587–1599. PubMed | CrossRef

Hoorens P, Rinaldi M, Mihi B, Dreesen L, et al. Galectin-11 induction in the gastrointestinal tract of cattle following nematode and protozoan infections. Parasite Immunol 2011; 33:669–678. View Full Text | PubMed | CrossRef

Hurrell JM, Genta RM, Melton SD. Histopathologic Diagnosis of Eosinophilic Conditions in the Gastrointestinal Tract. Adv Anat Pathol 2011; 18:335–348. PubMed | CrossRef

Hurst RJM, Else KJ. Retinoic acid signalling in gastrointestinal parasite infections: lessons from mouse models. Parasite Immunol 2012; 34:351–359. View Full Text | PubMed | CrossRef

Idris A, Moors E, Sohnrey B, Gauly M. Gastrointestinal nematode infections in German sheep. Parasitol Res 2012; 110:1453–1459. PubMed | CrossRef

▪. Kagalwalla AF, Akhtar N, Woodruff SA, et al. Eosinophilic esophagitis: Epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment. J Allergy Clin Immunol 2012; 129:1387–1396. e1387 [48]

Kolbaum J, Eschbach ML, Steeg C, Jacobs T, et al. Efficient control of Plasmodium yoelii infection in BALB/c and C57BL/6 mice with pre-existing Strongyloides ratti infection. Parasite Immunol 2012; 34:388–393. View Full Text | PubMed | CrossRef

▪▪. Linch SN, Danielson ET, Kelly AM, et al. Interleukin 5 is protective during sepsis in an eosinophil-independent manner. Am J Respir Crit Care Med 2012; 186:246–254. [112]

▪▪. Linch SN, Kelly AM, Danielson ET, et al. Mouse eosinophils possess potent antibacterial properties in vivo. Infect Immun 2009; 77:4976–4982. [102]

Maphosa V, Masika PJ. In vivo validation of Aloe ferox (Mill). Elephantorrhiza elephantina Bruch. Skeels. and Leonotis leonurus (L) R. BR as potential anthelminthics and antiprotozoals against mixed infections of gastrointestinal nematodes in goats. Parasitol Res 2012; 110:103–108. PubMed | CrossRef

▪. Morshed M, Yousefi S, Stockle C, et al. Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. Allergy 2012; 67:1127–1137. [94]

Navaneethan U, Venkatesh PGK, Downs-Kelly E, Shen B. Isospora belli superinfection in a patient with eosinophilic gastroenteritis-A diagnostic challenge. J Crohns Colitis 2012; 6:236–239. PubMed

Saddiqi HA, Jabbar A, Sarwar M, Iqbal Z, et al. Small ruminant resistance against gastrointestinal nematodes: a case of Haemonchus contortus. Parasitol Res 2011; 109:1483–1500. PubMed | CrossRef

Sagues MF, Fuse LA, Fernandez AS, Iglesias LE, et al. Efficacy of an energy block containing Duddingtonia flagrans in the control of gastrointestinal nematodes of sheep. Parasitol Res 2011; 109:707–713. PubMed | CrossRef

Verweij JJ, Van Lieshout L. Intestinal parasitic infections in an industrialized country; a new focus on children with better DNA-based diagnostics. Parasitology 2011; 138:1492–1498. View Full Text | PubMed | CrossRef

▪▪. Yousefi S, Gold JA, Andina N, et al. Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense. Nat Med 2008; 14:949–953. [93]

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Nod-like receptors in intestinal host defense: controlling pathogens, the microbiota, or both?

Review: (pp. 15–22)

Alfa MJ, Sepehri S, Olson N, Wald A. Establishing a clinically relevant bioburden benchmark: A quality indicator for adequate reprocessing and storage of flexible gastrointestinal endoscopes. Am J Infect Control 2012; 40:233–236.

Alonso CD, Treadway SB, Hanna DB, Huff CA, et al. Epidemiology and Outcomes of Clostridium difficile Infections in Hematopoietic Stem Cell Transplant Recipients. Clin Infect Dis 2012; 54:1053–1063. View Full Text | PubMed | CrossRef

▪. Bloom SM, Bijanki VN, Nava GM, et al. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe 2011; 9:390–403. [70]

Bonnel AR, Bunchorntavakul C, Reddy KR. Immune Dysfunction and Infections in Patients With Cirrhosis. Clin Gastroenterol Hepatol 2011; 9:727–738. PubMed | CrossRef

Canelo-Aybar C, Cuadra-Urteaga J, Atencia F, Romani F. Human T Lymphotropic virus-1 associated gastrointestinal histoplasmosis in Peru. J Infect Dev Ctries 2011; 5:484–488.

Carvalho A, Giovannini G, De Luca A, D'Angelo C, et al. Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis. Cell Mol Immunol 2012; 9:276–286. PubMed

▪. Chakrabarti S, Liehl P, Buchon N, Lemaitre B. Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut. Cell Host Microbe 2012; 12:60–70. [02]

Charalampopoulos D, Rastall RA. Prebiotics in foods. Curr Opin Biotechnol 2012; 23:187–191. PubMed

▪. Chassaing B, Rolhion N, de Vallee A, et al. Crohn disease: associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae. J Clin Invest 2011; 121:966–975. [37]

Chow J, Tang HQ, Mazmanian SK. Pathobionts of the gastrointestinal microbiota and inflammatory disease. Curr Opin Immunol 2011; 23:473–480. PubMed | CrossRef

de Smet A, Bonten MJM, Kluytmans J. For whom should we use selective decontamination of the digestive tract? Curr Opin Infect Dis 2012; 25:211–217.

Deretzi G, Kountouras J, Polyzos SA, Zavos C, et al. Gastrointestinal Immune System and Brain Dialogue Implicated in Neuroinflammatory and Neurodegenerative Diseases. Curr Mol Med 2011; 11:696–707. PubMed | CrossRef

▪. Dunbar TL, Yan Z, Balla KM, et al. C. elegans detects pathogen-induced translational inhibition to activate immune signaling. Cell Host Microbe 2012; 11:375–386. [03]

Du Pont HL. Gastrointestinal infections and the development of irritable bowel syndrome. Curr Opin Infect Dis 2011; 24:503–508.

El Hed A, Unutmaz D. Th17 cells and HIV infection. Curr Opin HIV AIDS 2010; 5:146–150.

Filler SG. Insights from human studies into the host defense against candidiasis. Cytokine 2012; 58:129–132. View Full Text | PubMed | CrossRef

▪. Fontana MF, Banga S, Barry KC, et al. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog 2011; 7:e1001289. [04]

▪. Franchi L, Kamada N, Nakamura Y, et al. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol 2012; 13:449–456. [50]

▪. Geddes K, Rubino SJ, Magalhaes JG, et al. Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nat Med 2011; 17:837–844. [41]

Gil-Campos M, Lopez MA, Rodriguez-Benitez MV, Romero J, et al. Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1-6 months of age: A Randomized Controlled Trial. Pharmacol Res 2012; 65:231–238. View Full Text | PubMed | CrossRef

Hao QK, Lu ZC, Dong BR, Huang CQ, et al. Probiotics for preventing acute upper respiratory tract infections - art. no. CD006895. Cochrane Database Syst Rev 2011; 6895.

▪. Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science 2012; 336:1268–1273. [53]

Israeli E, Agmon-Levin N, Blank M, Chapman J, et al. Guillain-Barre Syndrome-A Classical Autoimmune Disease Triggered by Infection or Vaccination. Clin Rev Allergy Immunol 2012; 42:121–130. View Full Text | PubMed | CrossRef

Jara S, Sanchez M, Vera R, Cofre J, et al. The inhibitory activity of Lactobacillus spp. isolated from breast milk on gastrointestinal pathogenic bacteria of nosocomial origin. Anaerobe 2011; 17:474–477. PubMed | CrossRef

▪. Kamada N, Kim YG, Sham HP, et al. Regulated virulence controls the ability of a pathogen to compete with the gut microbiota. Science 2012; 336:1325–1329. [81]

Klatt NR, Brenchley JM. Th17 cell dynamics in HIV infection. Curr Opin HIV AIDS 2010; 5:135–140.

▪. Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 2011; 477:592–595. [48]

Kusachi S, Sumiyama Y, Takahashi Y, Kato K, et al. Evaluation of the efficacy and safety of intravenous ciprofloxacin versus meropenem in the treatment of postoperative infection. J Infect Chemother 2012; 18:152–159. PubMed | CrossRef

Littman DR, Pamer EG. Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses. Cell Host Microbe 2011; 10:311–323. PubMed | CrossRef

Lye DJ. Gastrointestinal Colonization Rates for Human Clinical Isolates of Aeromonas Veronii Using a Mouse Model. Curr Microbiol 2011; 63:332–336. PubMed | CrossRef

Mann EA, Saeed SA. Gastrointestinal infection as a trigger for inflammatory bowel disease. Curr Opin Gastroenterol 2012; 28:24–29. View Full Text | PubMed | CrossRef

▪. McEwan DL, Kirienko NV, Ausubel FM. Host translational inhibition by Pseudomonas aeruginosa exotoxin A triggers an immune response in Caenorhabditis elegans. Cell Host Microbe 2012; 11:364–374. [05]

McFarland LV. Lactobacillus GG prevented nosocomial gastrointestinal and respiratory tract infections. Arch Dis Childhood-Educ Pract Ed 2011; 96:238.

▪. Melo JA, Ruvkun G. Inactivation of conserved C. elegans genes engages pathogen- and xenobiotic-associated defenses. Cell 2012; 149:452–466. [06]

Milner JD, Sandler NG, Douek DC. Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections. Curr Opin HIV AIDS 2010; 5:179–183. View Full Text | PubMed

Morrow LE, Gogineni V, Malesker MA. Probiotic, prebiotic, and synbiotic use in critically ill patients. Curr Opin Crit Care 2012; 18:186–191. View Full Text | PubMed | CrossRef

Munoz JAM, Chenoll E, Casinos B, Bataller E, et al. Novel Probiotic Bifidobacterium longum subsp infantis CECT 7210 Strain Active against Rotavirus Infections. Appl Environ Microbiol 2011; 77:8775–8783.

Nishiura H, Kido M, Aoki N, Iwamoto S, et al. Increased Susceptibility to Autoimmune Gastritis in Thymic Stromal Lymphopoietin Receptor-Deficient Mice. J Immunol 2012; 188:190–197. PubMed | CrossRef

O'Shea EF, O'Connor PM, Raftis EJ, O'Toole PW, et al. Production of Multiple Bacteriocins from a Single Locus by Gastrointestinal Strains of Lactobacillus salivarius. J Bacteriol 2011; 193:6973–6982. PubMed | CrossRef

Oertli M, Engler DB, Kohler E, Koch M, et al. MicroRNA-155 Is Essential for the T Cell-Mediated Control of Helicobacter pylori Infection and for the Induction of Chronic Gastritis and Colitis. J Immunol 2011; 187:3578–3586.

Paiardini M. Th17 cells in natural SIV hosts. Curr Opin HIV AIDS 2010; 5:166–172. View Full Text | PubMed

Panzer M, Sitte S, Wirth S, Drexler I, et al. Rapid In Vivo Conversion of Effector T Cells into Th2 Cells during Helminth Infection. J Immunol 2012; 188:615–623. PubMed | CrossRef

Ruiz P. How can pathologists help to diagnose late complications in small bowel and multivisceral transplantation? Curr Opin Organ Transpl 2012; 17:273–279.

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 1: Bacterial, viral and fungal infections. Clin Radiol 2012; 67:484–494. PubMed

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 2: Parasitic and other infections. Clin Radiol 2012; 67:495–504. PubMed

▪. Tattoli I, Sorbara MT, Vuckovic D, et al. Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host Microbe 2012; 11:563–575. [07]

Thomas LV, Ockhuizen T. New insights into the impact of the intestinal microbiota on health and disease: a symposium report. Br J Nutr 2012; 107:S1–S13. PubMed | CrossRef

▪. Ubeda C, Lipuma L, Gobourne A, et al. Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice. J Exp Med 2012; 209:1445–1456. [67]

van de Ven A, van Konijnenburg DPH, Wensing AMJ, van Montfrans JM. The Role of Prolonged Viral Gastrointestinal Infections in the Development of Immunodeficiency-Related Enteropathy. Clin Rev Allergy Immunol 2012; 42:79–91. View Full Text | PubMed | CrossRef

Walravens J, Brouwers J, Spriet I, Tack J, et al. Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole Monitoring of Intraluminal and Plasma Drug Concentrations. Clin Pharmacokinet 2011; 50:725–734. View Full Text | PubMed | CrossRef

Wong CCM, Zhang L, Ren SX, Shen J, et al. Antibacterial Peptides and Gastrointestinal Diseases. Curr Pharm Design 2011; 17:1583–1586.

▪. Zhao Y, Yang J, Shi J, et al. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 2011; 477:596–600. [49]

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Hospital management of children with acute gastroenteritis

Review: (pp. 23–30)

Ademola AD, Asinobi AO, Ogunkunle OO, Yusuf BN, et al. Peritoneal dialysis in childhood acute kidney injury: experience in southwest nigeria. Perit Dial Int 2012; 32:267–272. PubMed | CrossRef

▪. Al-Ansari K, Alomary S, Abdulateef H, et al. Metoclopramide versus Ondansetron for the treatment of vomiting in children with acute gastroenteritis. J Ped Gastroenterol Nutr 2011; 53:156–160. [28]

Boom JA, Sahni LC, Payne DC, Gautam R, et al. Symptomatic Infection and Detection of Vaccine and Vaccine-Reassortant Rotavirus Strains in 5 Children: A Case Series. J Infect Dis 2012; 206:1275–1279. View Full Text | PubMed | CrossRef

Cayley WE. Antiemetics for Acute Gastroenteritis-Related Vomiting in Children and Adolescents. Am Fam Physician 2012; 85:1054–1056. PubMed

Choong K, Arora S, Cheng J, Farrokhyar F, et al. Hypotonic Versus Isotonic Maintenance Fluids After Surgery for Children: A Randomized Controlled Trial. Pediatrics 2011; 128:857–866. PubMed | CrossRef

▪. Correa N, Penna FJ, Lime FMLS, et al. Treatment of acute diarrhea with Saccharomyces boulardii in Infants. J Pediatr Gastroenterol Nutr 2011; 53:497–501. [32]

▪▪. Desai R, Curns AT, Steiner CA, et al. All-Cause Gastroenteritis and Rotavirus-Coded Hospitalizations Among US Children, 2000–2009. Clin Infect Dis 2012; 55:e28–e34. [09]

Desai R, Curns AT, Steiner CA, Tate JE, et al. All-Cause Gastroenteritis and Rotavirus-Coded Hospitalizations Among US Children, 2000–2009. Clin Infect Dis 2012; 55:E28–E34. View Full Text | PubMed | CrossRef

Dinleyici EC, Eren M, Ozen M, Yargic ZA, et al. Effectiveness and safety of Saccharomyces boulardii for acute infectious diarrhea. Expert Opin Biol Ther 2012; 12:395–410. PubMed | CrossRef

▪▪. Fedorowicz Z, Jagannath VA, Carter B. Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents. Cochrane Database of Systematic Reviews 2011:CD005506. doi:0.1002/14651858.CD 005506.pub5. [21]

▪. Florescu DF, Hermsen ED, Kwon JY, et al. Is there a role for oral human immunoglobulin in the treatment for norovirus enteritis in immunocompromised patients? Pediatr Transpl 2011; 15:718–721. [51]

Fox J, Richards S, Jenkins HR, Powell C. Management of gastroenteritis over 10 years: changing culture and maintaining the change. Arch Dis Childhood-Educ Pract Ed 2012; 97:415–417.

Francavilla R, Lionetti E, Castellaneta S, Ciruzzi F, et al. Randomised clinical trial: Lactobacillus reuteri DSM 17938 vs. placebo in children with acute diarrhoea - a double-blind study. Aliment Pharmacol Ther 2012; 36:363–369. View Full Text | PubMed | CrossRef

▪. Francavilla R, Lionetti E, Castellaneta S, et al. Randomized clinical trial: Lactobacillus reuteri DSM 17938 vs placebo in children with acute diarrhea – a double blind study. Aliment Pharmacol Ther 2012; 36:363–369. [35]

▪▪. Freedman SB, Parkin PC, Willan AR, Schuh S. Rapid versus standard intravenous rehydration in paediatric gastroenteritis: pragmatic blinded randomized clinical trial. BMJ 2011; 343:d6976. [19]

▪▪. Freedman SB, Sivabalsundaram V, Bohn V, et al. The treatment of pediatric gastroenteritis: a comparative analysis of pediatric emergency physicians' practice patterns. Acad Emerg Med 2011; 18:38–45. [16]

▪. Freedman SB, Tung C, Cho D, et al. Time-series analysis of Ondansetron use in pediatric gastroenteritis. J Pediatr Gastroenterol Nutr 2012; 54:381–386. [20]

▪. Grandy G, Medina M, Soria R, et al. Probiotics in the treatment of acute rotavirus diarrhea. A randomized, double-blind, controlled trial using two different probiotic preparation in Bolivian children. BMC Infect Dis 2010; 10:253–259. [33]

▪▪. Guarino A, Dupont C, Gorelov AV, et al. The management of acute diarrhea in children in developed and developing areas. From evidence base to clinical practice. Expert Opin Pharmacother 2012; 13:17–26. [38]

Guarino A, Dupont C, Gorelov AV, Gottrand F, et al. The management of acute diarrhea in children in developed and developing areas: from evidence base to clinical practice. Expert Opin Pharmacother 2012; 13:17–26. PubMed | CrossRef

Hall AJ, Curns AT, McDonald LC, Parashar UD, et al. The Roles of Clostridium difficile and Norovirus Among Gastroenteritis-Associated Deaths in the United States, 1999–2007. Clin Infect Dis 2012; 55:216–223. View Full Text | PubMed | CrossRef

Howidi M, Al Kaabi N, El Khoury AC, Brandtmuller A, et al. Burden of acute gastroenteritis among children younger than 5 years of age - a survey among parents in the United Arab Emirates - art. no. 74. BMC Pediatr 2012; 12:18.

Kaiser P, Borte M, Zimmer KP, Huppertz HI. Complications in hospitalized children with acute gastroenteritis caused by rotavirus: a retrospective analysis. Eur J Pediatr 2012; 171:337–345. PubMed | CrossRef

▪▪. Lehert P, Cheron G, Calatayud GA, et al. Racecadotril for childhood gastroenteritis: an individual patient data meta-analysis. Dig Liver Dis 2011; 43:707–713. [39]

▪▪. Lo Vecchio A, Giannattasio A, Duggan C, et al. Evaluation of the quality guidelines for acute gastroenteritis in children with the AGREE instruement. J Pediatr Gastroenterol Nutr 2011; 52:183–189. [58]

▪▪. Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med 2011; 364:2483–2495. [18]

▪. Marchetti F, Maestro A, Rovere F, et al. Oral ondansetron versus domperidone for symptomatic treatment of vomiting during acute gastroenteritis in children: multicentre randomized controlled trial. BMC Pediatr 2011; 11:15–23. [27]

▪. Meng CY, Smith BL, Bodhidatta L, et al. Etiology of diarrhea in young children and patterns of antibiotic resistance in Cambodia. Pediatr Infect Dis J 2011; 30:331–335. [55]

Moritz ML, Ayus JC. Prevention of Hospital- Acquired Hyponatremia: Do We Have the Answers? Pediatrics 2011; 128:980–983.

▪. Mujawar QM, Naganoor R, Ali MD, et al. Efficacy of dioctahedral smectite in acute watery diarrhea in Indian children: a randomized clinical trial. J Trop Pediatr 2012; 58:63–67. [47]

▪▪. No Authors Given. Acute gastroenteritis guidelines Team, Cincinnati Children's Hospital Medical Center: evidence –based care guidelines for prevention and management of acute gastroenteritis in children aged 2 months to 18 years., http//http://www.cincinnatichildrens.org/service/j/Anderson-center/evidence–based-care/gastroenteritis/Guideline 5, pages I-20. [Accessed 21 December 2011]. [06]

▪. Nunez J, Liu DR, Nager AL. Dehydration treatment practices among pediatrics-trained and nonpediatrics trained emergency physicians. Pediatr Emer Care 2012; 28:322–328. [11]

▪. Opondo C, Ayieko P, Ntoburi S, et al. Effect of a multifaceted quality improvement intervention on inappropriate antibiotic use in children with nonbloody diarrhoea admitted to district hospitals in Kenya. BMC Pediatr 2011; 11:109. [53]

Ozmert EN, Ince OT, Orun E, Yalcin S, et al. Clinical characteristics and antibiotic resistance of Shigella gastroenteritis in Ankara, Turkey between 2003 and 2009, and comparison with previous reports. Int J Infect Dis 2011; 15:E849–E853. PubMed | CrossRef

Pammi M, Haque KN. Oral immunoglobulin for the treatment of rotavirus diarrhea in low birth weight infants - art. no. CD003742. Cochrane Database Syst Rev 2011; 3742.

▪. Passariello A, Terrin G, De Marco G, et al. Efficacy of a new hypotonic oral rehydration solution containing zinc and prebiotics in the treatment of childhood acute diarrhea: a randomized controlled trial. J Pediatr 2011; 158:228–292. [44]

▪. Pathak D, Pathak A, Marrone G, et al. Adherence to treatment guidelines for acute diarrhea in children up to 12 years in Ujjain, India: a cross-sectional prescription analysis. BMC Infectious Diseases 2011; 11:32–40. [37]

▪. Powell CVE, Priestley SJ, Young S, Heine RG. Randomized clinical trial of rapid versus 24-h rehydration for children with acute gastroenteritis. Pediatrics 2011; 218:e771. [13]

▪. Rahman S, Higo-Moriguchi K, Htun KW, et al. Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea among pediatric patients. Vaccine 2012; 30:4661–4669. [50]

Rahman S, Higo-Moriguchi K, Htun KW, Taniguchi K, et al. Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea among pediatric patients. Vaccine 2012; 30:4661–4669. PubMed | CrossRef

▪. Rautenberg TA, Zerwes U, Foerster D, Aultman R. Evaluating the cost utility of racecadotril for the treatment of acute watery diarrhea in children: the RAWD model. Clinicoecon Outcomes Res 2012; 4:109–116. [40]

Schuchmann S, Hauck S, Henning S, Gruters-Kieslich A, et al. Respiratory alkalosis in children with febrile seizures. Epilepsia 2011; 52:1949–1955. View Full Text | PubMed | CrossRef

▪. Vinh H, Anh VTC, Anh ND, et al. A Multi-Center Randomized Trial to Assess the Efficacy of Gatifloxacin versus Ciprofloxacin for the Treatment of Shigellosis in Vietnamese Children. PLoS Negl Trop Dis 2011; 5:e1264. [57]

▪. Wadhwa N, Natchu UC, Sommerfelt H, et al. ORS containing zinc does not reduce duration or stool volume of acute diarrhea in hospitalized children. J Pediatr Gastroenterol Nutr 2011; 53:161–167. [46]

▪. Wittenberg DF. Management guidelines for acute infective diarrhea/gastroenteritis in infants. S Afr Med J 2012; 102:104–107. [08]

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Functions of intestinal microflora in children

Review: (pp. 31–38)

Abrahamsson TR, Jakobsson HE, Andersson AF, Bjorksten B, et al. Low diversity of the gut microbiota in infants with atopic eczema. J Allergy Clin Immunol 2012; 129:434. View Full Text | PubMed | CrossRef

▪. Abrahamsson TR, Jakobsson HE, Andersson AF, et al. Low diversity of the gut microbiota in infants with atopic eczema. J Allergy Clin Immunol 2012; 129:434–440. 440 [45]

▪. Albesharat R, Ehrmann M, Korakli M, et al. Phenotypic and genotypic analyses of lactic acid bacteria in local fermented food, breast milk and faeces of mothers and their babies. Syst Appl Microbiol 2011; 34:148–155. [15]

▪. Angelakis E, Armougom F, Million M, Raoult D. The relationship between gut microbiota and weight gain in humans. Future Microbiol 2012; 7:91–109. [49]

▪▪. Arumugam M, Raes J, Pelletier E, et al. Enterotypes of the human gut microbiome. Nature 2011; 473:174–180. [04]

Bager P, Simonsen J, Nielsen NM, Frisch M. Cesarean section and offspring's risk of inflammatory bowel disease: A national cohort study. Inflamm Bowel Dis 2012; 18: 857–862. View Full Text | PubMed | CrossRef

▪▪. Bercik P, Denou E, Collins J, et al. The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology 2011; 141:599–609. [31]

Bezirtzoglou E, Stavropoulou E. Immunology and probiotic impact of the newborn and young children intestinal microflora. Anaerobe 2011; 17:369–374. PubMed | CrossRef

▪. Bezirtzoglou E, Tsiotsias A, Welling GW. Microbiota profile in feces of breast- and formula-fed newborns by using fluorescence in situ hybridization (FISH). Anaerobe 2011; 17:478–482. [16]

▪. Bisgaard H, Li N, Bonnelykke K, et al. Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age. J Allergy Clin Immunol 2011; 128:646–652. [46]

▪. Bonsante F, Iacobelli S, Gouyon JB. Routine probiotic use in very preterm infants: retrospective comparison of two cohorts. Am J Perinatol (in press). [60]

Brandi G, Biasco G, Mirarchi MG, Golfieri R, et al. A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma. Dig Liver Dis 2011; 43:1015–1021. PubMed | CrossRef

▪▪. Claesson MJ, Cusack S, O'Sullivan O, et al. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc Natl Acad Sci USA 2011; 108:4586–4591. [20]

▪▪. Cox MJ, Huang YJ, Fujimura KE, et al. Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PloS One 2010; 5:e8745. [55]

de St Groth BF. Regulatory T-cell abnormalities and the global epidemic of immuno-inflammatory disease. Immunol Cell Biol 2012; 90:256–259. View Full Text | PubMed | CrossRef

▪. Deshpande CG, Rao SC, Keil AD, Patole SK. Evidence-based guidelines for use of probiotics in preterm neonates. BMC Med 2011; 9:92–105. [62]

Djuardi Y, Wammes LJ, Supali T, Sartono E, et al. Immunological footprint: the development of a child's immune system in environments rich in microorganisms and parasites. Parasitology 2011; 138:1508–1518. View Full Text | PubMed | CrossRef

▪. Duytschaever G, Huys G, Bekaert M, et al. Cross-sectional and longitudinal comparisons of the predominant fecal microbiota compositions of a group of pediatric patients with cystic fibrosis and their healthy siblings. Appl Environ Microbiol 2011; 77:8015–8024. [57]

▪. Elinav E, Strowig T, Kau AL, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011; 145:745–757. [25]

Fageras M, Tomicic S, Voor T, Bjorksten B, et al. Slow Salivary Secretory IgA Maturation May Relate to Low Microbial Pressure and Allergic Symptoms in Sensitized Children. Pediatr Res 2011; 70:572–577. View Full Text | PubMed | CrossRef

▪. Gabrielli O, Zampini L, Galeazzi T, et al. Preterm milk oligosaccharides during the first month of lactation. Pediatrics 2011; 128:e1520–e1531. [14]

▪. Gerritsen J, Smidt H, Rijkers GT, de Vos WM. Intestinal microbiota in human health and disease: the impact of probiotics. Genes Nutr 2011; 6:209–240. [09]

▪. Gosiewski T, Strus M, Fyderek K, et al. Horizontal distribution of the fecal microbiota in adolescents with inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2012; 54:20–27. [39]

▪. Grześkowiak Ł, Collado MC, Mangani C, et al. Distinct gut microbiota in southeastern African and northern European infants. J Pediatr Gastroenterol Nutr 2012; 54:812–816. [08]

▪. Guarino A, Wudy A, Basile F, et al. Composition and roles of intestinal microbiota in children. J Matern Fetal Neonatal Med 2012; 25:63–66. [02]

Guarino A, Wudy A, Basile F, Ruberto E, et al. Composition and roles of intestinal microbiota in children. J Matern-Fetal Neonatal Med 2012; 25:63–66. PubMed | CrossRef

▪. Hansen CHF, Nielsen DS, Kverka M, et al. Patterns of early gut colonization shape future immune responses of the host. PLoS One 2012; 7:e34043. [12]

▪▪. Heijtz RD, Wang S, Anuar F, et al. Normal gut microbiota modulates brain development and behavior. Proc Natl Acad Sci USA 2011; 108:3047–3052. [32]

▪. Henao-Mejia J, Elinav E, Jin C, et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012; 482:179–185. [47]

Holmgren J, Svennerholm AM. Vaccines against mucosal infections. Curr Opin Immunol 2012; 24:343–353. PubMed | CrossRef

▪. Hooda S, Boler BMV, Serao MCR, et al. 454 pyrosequencing reveals a shift in fecal microbiota of healthy adult men consuming polydextrose or soluble corn fiber. J Nutr 2012; 142:1259–1265. [37]

▪▪. Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science 2012; 336:1268–1273. [21]

▪. Hoppu U, Isolauri E, Laakso P, et al. Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines. Eur J Nutr 2012; 51:211–219. [50]

▪. Horvath A, Dziechciarz P, Szajewska H. Meta-analysis: Lactobacillus rhamnosus GG for abdominal pain-related functional gastrointestinal disorders in childhood. Aliment Pharmacol Ther 2011; 33:1302–1310. [53]

Huh SY, Rifas-Shiman SL, Zera CA, Edwards JWR, et al. Delivery by caesarean section and risk of obesity in preschool age children: a prospective cohort study. Arch Dis Child 2012; 97:610–616. PubMed | CrossRef

▪. Huse SM, Ye Y, Zhou Y, Fodor A. A core human microbiome as viewed through 16 s rRNA sequence clusters. PLoS One 2012; 7:e34242. [03]

▪▪. Hviid A, Svanström H, Frisch M. Antibiotic use and inflammatory bowel diseases in childhood. Gut 2011; 60:49–54. [38]

Isolauri E. Development of healthy gut microbiota early in life. J Paediatr Child Health 2012; 48:1–6. View Full Text | PubMed | CrossRef

▪▪. Jacquot A, Neveu D, Aujoulat F, et al. Dynamics and clinical evolution of bacterial gut microflora in extremely premature patients. J Pediatr 2011; 158:390–396. [13]

▪▪. Jalanka-Tuovinen J, Salonen A, Nikkilä J, et al. Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. PloS One 2011; 6:e23035. [19]

Jan RL, Yeh KC, Hsieh MH, Lin YL, et al. Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma. Br J Nutr 2012; 108:130–139. PubMed | CrossRef

▪▪. Jumpertz R, Le DS, Turnbaugh PJ, et al. Energy-balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. Am J Clin Nutr 2011; 94:58–65. [29]

▪. Kinnebrew MA, Buffie CG, Diehl GE, et al. Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense. Immunity 2012; 36:276–287. [26]

▪▪. Koenig JE, Spor A, Scalfone N, et al. Succession of microbial consortia in the developing infant gut microbiome. Proc Natl Acad Sci USA 2011; 108:4578–4585. [18]

▪. Kosiewicz MM, Zirnheld AL, Alard P. Gut microbiota, immunity, and disease: a complex relationship. Front Microbiol 2011; 2:180. [28]

▪. Krajmalnik-Brown R, Ilhan Z-E, Kang D-W, Di Baise JK. Effects of gut microbes on nutrient absorption and energy regulation. Nutr Clin Pract 2012; 27:201–214. [48]

Lange NE, Celedon JC, Forno E, Ly NP, et al. Maternal intestinal flora and wheeze in early childhood. Clin Exp Allergy 2012; 42:901–908. PubMed

Lue KH, Sun HL, Lu KH, Ku MS, et al. A trial of adding Lactobacillus johnsonii EM1 to levocetirizine for treatment of perennial allergic rhinitis in children aged 7-12 years. Int J Pediatr Otorhinolaryngol 2012; 76:994–1001. PubMed | CrossRef

Lundell AC, Bjornsson V, Ljung A, Ceder M, et al. Infant B Cell Memory Differentiation and Early Gut Bacterial Colonization. J Immunol 2012; 188:4315–4322. PubMed | CrossRef

▪. Luoto R, Kalliomäki M, Laitinen K, et al. Initial dietary and microbiological environments deviate in normal-weight compared to overweight children at 10 years of age. J Pediatr Gastroenterol Nutr 2011; 52:90–95. [51]

▪. Ly NP, Litonjua A, Gold DR, Celedón JC. Gut microbiota, probiotics, and vitamin D: interrelated exposures influencing allergy, asthma, and obesity? J Allergy Clin Immunol 2011; 127:1087–1094. [44]

▪▪. Mai V, Young CM, Ukhanova M, et al. Fecal microbiota in preterm infants prior to necrotizing enterocolitis. PloS One 2011; 6:e20647. [43]

Marild K, Stephansson O, Montgomery S, Murray JA, et al. Pregnancy Outcome and Risk of Celiac Disease in Offspring: A Nationwide Case-Control Study. Gastroenterology 2012; 142:39.

Masuda Y, Takahashi T, Yoshida K, Nishitani Y, et al. Anti-allergic effect of lactic acid bacteria isolated from seed mash used for brewing sake is not dependent on the total IgE levels. J Biosci Bioeng 2012; 114:292–296. PubMed | CrossRef

▪. Mihatsch WA, Braegger CP, Decsi T, et al. Critical systematic review of the level of evidence for routine use of probiotics for reduction of mortality and prevention of necrotizing enterocolitis and sepsis in preterm infants. Clin Nutr 2012; 31:6–15. [63]

Nakayama J, Kobayashi T, Tanaka S, Korenori Y, et al. Aberrant structures of fecal bacterial community in allergic infants profiled by 16S rRNA gene pyrosequencing. FEMS Immunol Med Microbiol 2011; 63:397–406. View Full Text | PubMed | CrossRef

▪. Neu J. Routine probiotics for premature infants: let's be careful!. J Pediatr 2011; 158:672–674. [64]

▪. Nicholson JK, Holmes E, Kinross J, et al. Host-gut microbiota metabolic interactions. Science 2012; 336:1262–1267. [30]

Nistal E, Caminero A, Herran AR, Arias L, et al. Differences of small intestinal bacteria populations in adults and children with/without celiac disease: Effect of age, gluten diet, and disease. Inflamm Bowel Dis 2012; 18:649–656. View Full Text | PubMed | CrossRef

▪▪. No Authors Given. Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–14. [01]

▪▪. Pimentel M, Lembo A, Chey WD, et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med 2011; 364:22–32. [52]

▪▪. Round JL, Lee SM, Li J, Tran G, et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011; 332:974–977. [27]

▪▪. Saulnier DM, Riehle K, Mistretta T-A, et al. Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome. Gastroenterology 2011; 141:1782–1791. [40]

▪▪. Scanlan PD, Buckling A, Kong W, et al. Gut dysbiosis in cystic fibrosis. J Cyst Fibros (in press). [59]

▪▪. Sellitto M, Bai G, Serena G, et al. Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants. PloS One 2012; 7:e33387. [34]

▪. Simrén M, Barbara G, Flint HJ, et al. Intestinal microbiota in functional bowel disorders: a Rome foundation report. Gut (in press). [56]

▪▪. Smith B, Bodé S, Skov TH, et al. Investigation of the early intestinal microflora in premature infants with/without necrotizing enterocolitis using two different methods. Pediatr Res 2012; 71:115–120. [42]

▪▪. Sonnenberg GF, Monticelli LA, Alenghat T, et al. Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria. Science 2012; 336:1321–1325. [23]

▪. Spits H, Di Santo JP. The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol 2011; 12:21–27. [22]

Storro O, Oien T, Langsrud O, Rudi K, et al. Temporal variations in early gut microbial colonization are associated with allergen-specific immunoglobulin E but not atopic eczema at 2 years of age. Clin Exp Allergy 2011; 41:1545–1554. PubMed | CrossRef

Sutherland JB, Bridges BM, Heinze TM, Adams MR, et al. Comparison of the Effects of Antimicrobial Agents from Three Different Classes on Metabolism of Isoflavonoids by Colonic Microflora Using Etest Strips. Curr Microbiol 2012; 64:60–65. PubMed | CrossRef

▪. Swidsinski A, Dorffel Y, Loening-Baucke V, et al. Acute appendicitis is characterized by local invasion with Fusobacterium nucleatum/necrophorum. Gut 2011; 60:34–40. [36]

Thompson AL. Developmental origins of obesity: Early feeding environments, infant growth, and the intestinal microbiome. Am J Hum Biol 2012; 24:350–360. PubMed | CrossRef

▪. Turroni F, Peano C, Pass D, et al. Diversity of bifidobacteria within the infant gut microbiota. PLoS One 2012; 7:e36957. [17]

▪. Vaishnava S, Yamamoto M, Severson KM, et al. The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science 2011; 334:255–258. [24]

▪. van Nimwegen FA, Penders J, Stobberingh EE, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. J Allergy Clin Immunol 2011; 128:948–955. e1–e3 [11]

van Nimwegen FA, Penders J, Stobberingh EE, Postma DS, et al. Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. J Allergy Clin Immunol 2011; 128:948. View Full Text | PubMed | CrossRef

Wada K, Nakamura K, Tamai Y, Tsuji M, et al. Seaweed intake and urinary sex hormone levels in preschool Japanese children. Cancer Causes Control 2012; 23:239–244. PubMed | CrossRef

▪. Wu GD, Chen J, Hoffmann C, et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334:105–108. [06]

Yang YJ, Sheu BS. Probiotics-Containing Yogurts Suppress Helicobacter pylori Load and Modify Immune Response and Intestinal Microbiota in the Helicobacter pylori-Infected Children. Helicobacter 2012; 17:297–304. View Full Text | PubMed | CrossRef

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Development of a norovirus vaccine

Haroon M, Martin U, Devlin J. High incidence of intolerance to tuberculosis chemoprophylaxis. Rheumatol Int 2012; 32:33–37. PubMed | CrossRef

Skok P, Sinkovic A. Upper Gastrointestinal Haemorrhage: Predictive Factors of In-hospital Mortality in Patients Treated in the Medical Intensive Care Unit. J Int Med Res 2011; 39:1016–1027. PubMed | CrossRef

Vega J, Vide la C, Borja H, Goecke H, et al. Causes of death with a functioning graft among kidney allograft recipients. Rev Medica Chile 2012; 140:295–304.

Zhong YH, Fang Y, Zhou JZ, Tang Y, et al. Effectiveness and Safety of Patient-initiated Single-dose versus Continuous Low-dose Antibiotic Prophylaxis for Recurrent Urinary Tract Infections in Postmenopausal Women: a Randomized Controlled Study. J Int Med Res 2011; 39:2335–2343. PubMed | CrossRef

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Food safety lessons from the German outbreak of E coli 0104:H4

Buvens G, Pierard D. Infections with verotoxin-producing escherichia coli o157:h7 and other serotypes, including the outbreak strain o104:h4. Acta Clin Belg 2012; 67:7–12. PubMed | CrossRef

Lukyanenko V, Malyukova I, Hubbard A, De lannoy M, et al. Enterohemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells. Am J Physiol-Cell Physiol 2011; 301:C1140–C1149. PubMed | CrossRef

Neil KP, Biggerstaff G, MacDonald JK, Trees E, et al. A Novel Vehicle for Transmission of Escherichia coli O157:H7 to Humans: Multistate Outbreak of E. coli O157:H7 Infections Associated With Consumption of Ready-to-Bake Commercial Prepackaged Cookie Dough-United States, 2009. Clin Infect Dis 2012; 54:511–518. View Full Text | PubMed | CrossRef

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GI infections following transplantation

Alonso CD, Treadway SB, Hanna DB, Huff CA, et al. Epidemiology and Outcomes of Clostridium difficile Infections in Hematopoietic Stem Cell Transplant Recipients. Clin Infect Dis 2012; 54:1053–1063. View Full Text | PubMed | CrossRef

Bejanyan N, Bolwell BJ, Lazaryan A, Rybicki L, et al. Risk Factors for 30-Day Hospital Readmission following Myeloablative Allogeneic Hematopoietic Cell Transplantation (allo-HCT). Biol Blood Marrow Transplant 2012; 18:874–880. PubMed | CrossRef

Blombery P, Prince HM, Worth LJ, Main J, et al. Prophylactic intravenous immunoglobulin during autologous haemopoietic stem cell transplantation for multiple myeloma is not associated with reduced infectious complications. Ann Hematol 2011; 90:1167–1172. View Full Text | PubMed | CrossRef

Bonnel AR, Bunchorntavakul C, Reddy KR. Immune Dysfunction and Infections in Patients With Cirrhosis. Clin Gastroenterol Hepatol 2011; 9:727–738. PubMed | CrossRef

Gowdy KM, Cardona DM, Nugent JL, Giamberardino C, et al. Novel Role for Surfactant Protein A in Gastrointestinal Graft-versus-Host Disease. J Immunol 2012; 188:4897–4905. PubMed | CrossRef

Khameneh ZR, Sepehrvand N, Hatami S, Afshari AT. The Seroprevalence of Helicobacter pylori Infection in Renal Transplant Recipients. Transplant Proc 2011; 43:3720–3722. PubMed | CrossRef

Kumar L, Malik PS, Prakash G, Prabu R, et al. Autologous hematopoietic stem cell transplantation-what determines the outcome: an experience from North India. Ann Hematol 2011; 90:1317–1328. View Full Text | PubMed | CrossRef

Lempinen M, Halme L, Arola J, Honkanen E, et al. HHV-6B is frequently found in the gastrointestinal tract in kidney transplantation patients. Transpl Int 2012; 25:776–782. View Full Text | PubMed | CrossRef

Mousset S, Martin H, Berger A, Hess S, et al. Human herpesvirus 6 in biopsies from patients with gastrointestinal symptoms after allogeneic stem cell transplantation. Ann Hematol 2012; 91:737–742. View Full Text | PubMed | CrossRef

Petrikkos G, Skiada A, Lortholary O, Roilides E, et al. Epidemiology and Clinical Manifestations of Mucormycosis. Clin Infect Dis 2012; 54:S23–S34. View Full Text | PubMed | CrossRef

Valentin T, Neumeister P, Pichler M, Rohn A, et al. Disseminated Geosmithia argillacea infection in a patient with gastrointestinal GvHD. Bone Marrow Transplant 2012; 47:734–736. View Full Text | PubMed | CrossRef

Whitman CB, Czosnowski QA. Fidaxomicin for the Treatment of Clostridium difficile infections. Ann Pharmacother 2012; 46:219–228. PubMed | CrossRef

Wudhikarn K, Perry EH, Kemperman M, Jensen KA, et al. Transfusion-transmitted Babesiosis in an Immunocompromised Patient: A Case Report and Review. Am J Med 2011; 124:800–805. PubMed | CrossRef

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Investigation of gastrointestinal infection

Alfano-Sobsey E, Sweat D, Hall A, Breedlove F, et al. Norovirus outbreak associated with undercooked oysters and secondary household transmission. Epidemiol Infect 2012; 140:276–282. View Full Text | PubMed | CrossRef

Asmundsdottir LR, Erlendsdottir H, Gisladottir AL, Gottfredsson M. Molecular epidemiology of late recurrent candidaemiaua population-based study in Iceland. Clin Microbiol Infect 2012; 18:195–201. View Full Text | PubMed | CrossRef

Baumann-Popczyk A, Sadkowska-Todys M, Rogalska J, Stefanoff P. Incidence of self-reported acute gastrointestinal infections in the community in Poland: a population-based study. Epidemiol Infect 2012; 140:1173–1184. View Full Text | PubMed | CrossRef

Borges S, Silva J, Teixeira P. Survival and biofilm formation by Group B streptococci in simulated vaginal fluid at different pHs. Antonie Van Leeuwenhoek 2012; 101:677–682. PubMed | CrossRef

Burke JS. Lymphoproliferative Disorders of the Gastrointestinal Tract A Review and Pragmatic Guide to Diagnosis. Arch Pathol Lab Med 2011; 135:1283–1297. PubMed | CrossRef

Chahine EB, Ferrill MJ, Poulakos MN. Doripenem: A new carbapenem antibiotic. Am J Health-Syst Pharm 2010; 67:2015–2024. View Full Text | PubMed | CrossRef

Choisy C. Biofilms and public health. Bull Acad Natl Med 2011; 195:1105–1118. PubMed

Dhingra S, Wang HM. Nonneoplastic signet-ring cell change in gastrointestinal and biliary tracts: a pitfall for overdiagnosis. Ann Diagn Pathol 2011; 15:490–496. PubMed | CrossRef

Dolatkhah R, Khoshbaten M, Kermani IA, Bonyadi MR, et al. Upper gastrointestinal bleedings in patients with hereditary coagulation disorders in Northwest of Iran: prevalence of Helicobacter pylori infection. Eur J Gastroenterol Hepatol 2011; 23:1172–1177. View Full Text | PubMed | CrossRef

Gijsbers CFM, Kneepkens CMF, Schweizer JJ, Benninga MA, et al. Recurrent abdominal pain in 200 children: somatic causes and diagnostic criteria. Acta Paediatr 2011; 100:E208–E214. View Full Text | PubMed | CrossRef

Grinberg A, Pomroy WE, Squires RA, Scuffham A, et al. Retrospective cohort study of an outbreak of cryptosporidiosis caused by a rare Cryptosporidium parvum subgenotype. Epidemiol Infect 2011; 139:1542–1550. View Full Text | PubMed | CrossRef

Kang KH, Jeong KH, Baik SK, Huh WY, et al. Purple urine bag syndrome: case report and literature review. Clin Nephrol 2011; 75:557–559. PubMed | CrossRef

Kawai T, Goto A, Watanabe E, Nagasawa M, et al. Lower respiratory tract infections and gastrointestinal infections among mature babies in Japan. Pediatr Int 2011; 53:431–445. View Full Text | PubMed

Muller L, Korsgaard H, Ethelberg S. Burden of acute gastrointestinal illness in Denmark 2009: a population-based telephone survey. Epidemiol Infect 2012; 140:290–298. View Full Text | PubMed | CrossRef

Murakami K, Kamada T, Ishikawa H, Imamura H, et al. An Evaluation of the Performance of a Novel Stick-Type Kit for Rapid Detection of Helicobacter Pylori Antibodies in Urine. Clin Lab 2011; 57:481–487. PubMed

Murakami K, Takahashi R, Ono M, Watanabe K, et al. Serodiagnosis of Helicobacter hepaticus infection in patients with liver and gastrointestinal diseases: western blot analysis and ELISA using a highly specific monoclonal antibody for H. hepaticus antigen. J Gastroenterol 2011; 46:1120–1126. PubMed | CrossRef

Nagata N, Marriott D, Harkness J, Ellis JT, et al. In Vitro Susceptibility Testing of Dientamoeba fragilis. Antimicrob Agents Chemother 2012; 56:487–494. PubMed | CrossRef

Nseir W, Mograbi J, Di Castro N, Abu-Elheja O, et al. On the Association Between Soft Drink Consumption and Helicobacter pylori Infection. Dig Dis Sci 2012; 57:981–986. View Full Text | PubMed | CrossRef

Onanuga A, Temedie TC. Multidrug-resistant Intestinal Staphylococcus aureus among Self-medicated Healthy Adults in Amassoma, South-South, Nigeria. J Heatlh Popul Nutr 2011; 29:446–453.

Partridge DG, Evans CM, Raza M, Kudesia G, et al. Lessons from a large norovirus outbreak: impact of viral load, patient age and ward design on duration of symptoms and shedding and likelihood of transmission. J Hosp Infect 2012; 81:25–30. PubMed | CrossRef

Petrikkos G, Skiada A, Lortholary O, Roilides E, et al. Epidemiology and Clinical Manifestations of Mucormycosis. Clin Infect Dis 2012; 54:S23–S34. View Full Text | PubMed | CrossRef

Phan VTM, Rabaa MA, Vinh H, Holmes EC, et al. The Emergence of Rotavirus G12 and the Prevalence of Enteric Viruses in Hospitalized Pediatric Diarrheal Patients in Southern Vietnam. Am J Trop Med Hyg 2011; 85:768–775. PubMed | CrossRef

Porter CK, Gloor K, Cash BD, Riddle MS. Risk of Functional Gastrointestinal Disorders in U.S. Military Following Self-Reported Diarrhea and Vomiting During Deployment. Dig Dis Sci 2011; 56:3262–3269. View Full Text | PubMed | CrossRef

Rimhanen-Finne R, Jokiranta TS, Virtanen MJ, Kuusi M. Giardia and Cryptosporidium infection in Finland: a registry-based study of their demographic determinants. Apmis 2011; 119:735–740. PubMed | CrossRef

Salisbury AM, Bronowski C, Wigley P. Salmonella Virchow isolates from human and avian origins in England - molecular characterization and infection of epithelial cells and poultry. J Appl Microbiol 2011; 111:1505–1514. PubMed | CrossRef

Scavia G, Baldinelli F, Busani L, Caprioli A. The burden of self-reported acute gastrointestinal illness in Italy: a retrospective survey, 2008–2009. Epidemiol Infect 2012; 140:1193–1206. View Full Text | PubMed | CrossRef

Silva MVB, Sonstegard TS, Hanotte O, Mugambi JM, et al. Identification of quantitative trait loci affecting resistance to gastrointestinal parasites in a double backcross population of Red Maasai and Dorper sheep. Anim Genet 2012; 43:63–71. View Full Text | PubMed | CrossRef

Snyder GM, D'Agata EMC. Diagnostic accuracy of surveillance cultures to detect gastrointestinal colonization with multidrug-resistant gram-negative bacteria. Am J Infect Control 2012; 40:474–476.

Sonnenberg A, Genta RM. Low prevalence of Helicobacter pylori infection among patients with inflammatory bowel disease. Aliment Pharmacol Ther 2012; 35:469–476. View Full Text | PubMed | CrossRef

Su CY, Pei J, Lu XH, Tang W, et al. Gastrointestinal symptoms predict peritonitis rates in CAPD patients. Clin Nephrol 2012; 77:267–274. PubMed | CrossRef

Verweij JJ, Van Lieshout L. Intestinal parasitic infections in an industrialized country; a new focus on children with better DNA-based diagnostics. Parasitology 2011; 138:1492–1498. View Full Text | PubMed | CrossRef

Vikram HR, Smilack JD, Leighton JA, Crowell MD, et al. Emergence of Gastrointestinal Basidiobolomycosis in the United States, With a Review of Worldwide Cases. Clin Infect Dis 2012; 54:1685–1691.

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Management of gastrointestinal infection

Archibald LK, Jarvis WR. Health Care-Associated Infection Outbreak Investigations by the Centers for Disease Control and Prevention, 1946–2005. Am J Epidemiol 2011; 174:S47–S64. View Full Text | PubMed | CrossRef

Beechler BR, Broughton H, Bell A, Ezenwa VO, et al. Innate Immunity in Free-Ranging African Buffalo (Syncerus caffer): Associations with Parasite Infection and White Blood Cell Counts. Physiol Biochem Zool 2012; 85:255–264. PubMed | CrossRef

Borgaonkar MR, Hookey L, Hollingworth R, Kuipers EJ, et al. Indicators of safety compromise in gastrointestinal endoscopy. Can J Gastroenterol 2012; 26:71–78. PubMed

Chahine EB, Ferrill MJ, Poulakos MN. Doripenem: A new carbapenem antibiotic. Am J Health-Syst Pharm 2010; 67:2015–2024. View Full Text | PubMed | CrossRef

Chavez-Tapia NC, Barrientos-Gutierrez T, Tellez-Avila F, Soares-Weiser K, et al. Meta-analysis: antibiotic prophylaxis for cirrhotic patients with upper gastrointestinal bleeding - an updated Cochrane review. Aliment Pharmacol Ther 2011; 34:509–518. PubMed | CrossRef

Choi WS, Kim MJ, Park DW, Son SW, et al. Clarithromycin and amikacin vs. clarithromycin and moxifloxacin for the treatment of post-acupuncture cutaneous infections due to Mycobacterium abscessus: a prospective observational study. Clin Microbiol Infect 2011; 17:1084–1090. View Full Text | PubMed | CrossRef

Cornely OA, Helfgott D, Langston A, Heinz W, et al. Pharmacokinetics of Different Dosing Strategies of Oral Posaconazole in Patients with Compromised Gastrointestinal Function and Who Are at High Risk for Invasive Fungal Infection. Antimicrob Agents Chemother 2012; 56: 2652–2658. PubMed | CrossRef

Coyle CM, Varughese J, Weiss LM, Tanowitz HB. Blastocystis: To Treat or Not to Treat. Clin Infect Dis 2012; 54:105–110. PubMed | CrossRef

Crawford T, Huesgen E, Danziger L. Fidaxomicin: A novel macrocyclic antibiotic for the treatment of Clostridium difficile infection. Am J Health-Syst Pharm 2012; 69:933–943. View Full Text | PubMed | CrossRef

Dolton MJ, Ray JE, Marriott D, McLachlan AJ. Posaconazole Exposure-Response Relationship: Evaluating the Utility of Therapeutic Drug Monitoring. Antimicrob Agents Chemother 2012; 56:2806–2813.

Ewaschuk JB, Murdoch GK, Johnson IR, Madsen KL, et al. Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infection. Br J Nutr 2011; 106:870–877. PubMed | CrossRef

Ezaki S, Itoh K, Kunikata T, Suzuki K, et al. Prophylactic Probiotics Reduce Cow's Milk Protein Intolerance in Neonates after Small Intestine Surgery and Antibiotic Treatment Presenting Symptoms That Mimics Postoperative Infection. Allergol Int 2012; 61:107–113. PubMed | CrossRef

Fujitani K, Tsujinaka T, Fujita J, Miyashiro I, et al. Prospective randomized trial of preoperative enteral immunonutrition followed by elective total gastrectomy for gastric cancer. Br J Surg 2012; 99:621–629. View Full Text | PubMed | CrossRef

Gil-Campos M, Lopez MA, Rodriguez-Benitez MV, Romero J, et al. Lactobacillus fermentum CECT 5716 is safe and well tolerated in infants of 1-6 months of age: A Randomized Controlled Trial. Pharmacol Res 2012; 65:231–238. View Full Text | PubMed | CrossRef

Gough E, Shaikh H, Manges AR. Systematic Review of Intestinal Microbiota Transplantation (Fecal Bacteriotherapy) for Recurrent Clostridium difficile Infection. Clin Infect Dis 2011; 53:994–1002. View Full Text | PubMed | CrossRef

Guo B, Harstall C, Louie T, van Zanten SV, et al. Systematic review: faecal transplantation for the treatment of Clostridium difficile-associated disease. Aliment Pharmacol Ther 2012; 35:865–875.

Hardesty JS, Juang P. Fidaxomicin: A Macrocyclic Antibiotic for the Treatment of Clostridium difficile Infection. Pharmacotherapy 2011; 31:877–886. View Full Text | PubMed | CrossRef

Hurdle JG, Heathcott AE, Yang L, Yan B, et al. Reutericyclin and related analogues kill stationary phase Clostridium difficile at achievable colonic concentrations. J Antimicrob Chemother 2011; 66:1773–1776. View Full Text | PubMed | CrossRef

Ilic K, Jakovljevic E, Skodric-Trifunovic V. Social-economic factors and irrational antibiotic use as reasons for antibiotic resistance of bacteria causing common childhood infections in primary healthcare. Eur J Pediatr 2012; 171:767–777. PubMed | CrossRef

Kappelman MD, Dorn SD, Peterson E, Runge T, et al. Quality of Care for Gastrointestinal Conditions: A Primer for Gastroenterologists. Am J Gastroenterol 2011; 106:1182–1187. PubMed | CrossRef

Kolbaum J, Eschbach ML, Steeg C, Jacobs T, et al. Efficient control of Plasmodium yoelii infection in BALB/c and C57BL/6 mice with pre-existing Strongyloides ratti infection. Parasite Immunol 2012; 34:388–393. View Full Text | PubMed | CrossRef

Landy J, Al-Hassi HO, McLaughlin SD, Walker AW, et al. Review article: faecal transplantation therapy for gastrointestinal disease. Aliment Pharmacol Ther 2011; 34:409–415. View Full Text | PubMed | CrossRef

Mascarello M, Gobbi F, Angheben A, Gobbo M, et al. Prevalence of Strongyloides stercoralis infection among HIV-positive immigrants attending two Italian hospitals, from 2000 to 2009. Ann Trop Med Parasitol 2011; 105:617–623. PubMed | CrossRef

Miyagaki H, Nakajima K, Hara J, Yamasaki M, et al. Performance comparison of peripherally inserted central venous catheters in gastrointestinal surgery: A randomized controlled trial. Clin Nutr 2012; 31:48–52. PubMed | CrossRef

Mohan HM, McDermott S, Fenelon L, Fearon NM, et al. Plastic wound retractors as bacteriological barriers in gastrointestinal surgery: a prospective multi-institutional trial. J Hosp Infect 2012; 81:109–113. PubMed | CrossRef

Muller L, Korsgaard H, Ethelberg S. Burden of acute gastrointestinal illness in Denmark 2009: a population-based telephone survey. Epidemiol Infect 2012; 140:290–298. View Full Text | PubMed | CrossRef

Munoz JAM, Chenoll E, Casinos B, Bataller E, et al. Novel Probiotic Bifidobacterium longum subsp infantis CECT 7210 Strain Active against Rotavirus Infections. Appl Environ Microbiol 2011; 77:8775–8783.

Naf F, Warschkow R, Kolb W, Zund M, et al. Selective decontamination of the gastrointestinal tract in patients undergoing esophageal resection - art. no. 36. BMC Surg 2010; 10:16.

Nielsen HH, Qiu J, Friis S, Wermuth L, et al. Treatment for Helicobacter pylori infection and risk of parkinson's disease in Denmark. Eur J Neurol 2012; 19:864–869. View Full Text | PubMed | CrossRef

Nigro N, Muller B, Morgenthaler NG, Fluri F, et al. The use of copeptin, the stable peptide of the vasopressin precursor, in the differential diagnosis of sodium imbalance in patients with acute diseases - art. no. w13270. Swiss Med Wkly 2011; 141:11.

Peel T, Cheng AC, Spelman T, Huysmans M, et al. Differing risk factors for vancomycin-resistant and vancomycin-sensitive enterococcal bacteraemia. Clin Microbiol Infect 2012; 18:388–394. View Full Text | PubMed | CrossRef

Perez-Ayala A, Perez-Molina JA, Norman F, Navarro M, et al. Chagas disease in Latin American migrants: a Spanish challenge. Clin Microbiol Infect 2011; 17:1108–1113. View Full Text | PubMed | CrossRef

Rammaert B, Lanternier F, Zahar JR, Dannaoui E, et al. Healthcare-Associated Mucormycosis. Clin Infect Dis 2012; 54:S44–S54.

Rees K, Stowe R, Patel S, Ives N, et al. Helicobacter pylori eradication for Parkinson's disease - art. no. CD008453. Cochrane Database Syst Rev 2011; 8453.

Reuken PA, Pletz MW, Baier M, Pfister W, et al. Emergence of spontaneous bacterial peritonitis due to enterococci - risk factors and outcome in a 12-year retrospective study. Aliment Pharmacol Ther 2012; 35:1199–1208. View Full Text | PubMed | CrossRef

Roos D, Dijksman LM, Oudemans-van Straaten HM, de Wit LT, et al. Randomized clinical trial of perioperative selective decontamination of the digestive tract versus placebo in elective gastrointestinal surgery. Br J Surg 2011; 98:1365–1372. View Full Text | PubMed | CrossRef

Roquer J, Cuadrado-Godia E, Giralt-Steinthauer E, Jimena S, et al. Previous Infection and Stroke: A Prospective Study. Cerebrovasc Dis 2012; 33:310–315. View Full Text | PubMed | CrossRef

Sagues MF, Fuse LA, Fernandez AS, Iglesias LE, et al. Efficacy of an energy block containing Duddingtonia flagrans in the control of gastrointestinal nematodes of sheep. Parasitol Res 2011; 109:707–713. PubMed | CrossRef

Scavia G, Baldinelli F, Busani L, Caprioli A. The burden of self-reported acute gastrointestinal illness in Italy: a retrospective survey, 2008–2009. Epidemiol Infect 2012; 140:1193–1206. View Full Text | PubMed | CrossRef

Seron-Arbeloa C, Puzo-Foncillas J, Garces-Gimenez T, Escos-Orta J, et al. A retrospective study about the influence of early nutritional support on mortality and nosocomial infection in the critical care setting. Clin Nutr 2011; 30:346–350. PubMed | CrossRef

Sherwood V, King E, Totemeyer S, Connerton I, et al. Interferon treatment suppresses enteric adenovirus infection in a model gastrointestinal cell-culture system. J Gen Virol 2012; 93:618–623. PubMed | CrossRef

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 1: Bacterial, viral and fungal infections. Clin Radiol 2012; 67:484–494. PubMed

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 2: Parasitic and other infections. Clin Radiol 2012; 67:495–504. PubMed

Southern KW, Barker PM, Solis-Moya A, Patel L. Macrolide antibiotics for cystic fibrosis - art. no. CD002203. Cochrane Database Syst Rev 2011; 2203.

Stevens DL, Aldape MJ, Bryant AE. Life-threatening clostridial infections. Anaerobe 2012; 18:254–259.

Sweeney DA, Hicks CW, Cui XZ, Li Y, et al. Anthrax Infection. Am J Respir Crit Care Med 2011; 184:1333–1341. PubMed | CrossRef

Thomas L, Moravie V, Besnier F, Valentino R, et al. Clinical Presentation of Dengue Among Patients Admitted to the Adult Emergency Department of a Tertiary Care Hospital in Martinique: Implications for Triage, Management, and Reporting. Ann Emerg Med 2012; 59:42–50. PubMed | CrossRef

Walravens J, Brouwers J, Spriet I, Tack J, et al. Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole Monitoring of Intraluminal and Plasma Drug Concentrations. Clin Pharmacokinet 2011; 50:725–734. View Full Text | PubMed | CrossRef

Whitman CB, Czosnowski QA. Fidaxomicin for the Treatment of Clostridium difficile infections. Ann Pharmacother 2012; 46:219–228. PubMed | CrossRef

Wudhikarn K, Perry EH, Kemperman M, Jensen KA, et al. Transfusion-transmitted Babesiosis in an Immunocompromised Patient: A Case Report and Review. Am J Med 2011; 124:800–805. PubMed | CrossRef

Yogeswaran K, Chen G, Cohen L, Cooper MA, et al. How well is Helicobacter pylori treated in usual practice? Can J Gastroenterol 2011; 25:543–546.

Zhang Y, Gu YH, Guo TK, Li YP, et al. Perioperative immunonutrition for gastrointestinal cancer: A systematic review of randomized controlled trials. Surg Oncol-Oxf 2012; 21:E87–E95.

Zhang YY, Zhou X. Efficacy and safety of intravenous itraconazole followed by oral itraconazole solution in the treatment of invasive pulmonary mycosis. Chin Med J 2011; 124:3415–3419. PubMed

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Factors affecting gastrointestinal infection

Agaimy A, Mudter J, Markl B, Chetty R. Cytomegalovirus infection presenting as isolated inflammatory polyps of the gastrointestinal tract. Pathology 2011; 43:440–446. View Full Text | PubMed | CrossRef

Akahane T, Nagata M, Matsumoto T, Murayama N, et al. A case of wound dual infection with pasteurella dagmatis and pasteurella canis resulting from a dog bite - limitations of vitek-2 system in exact identification of pasteurella species. Eur J Med Res 2011; 16:531–536. PubMed | CrossRef

Alfa MJ, Sepehri S, Olson N, Wald A. Establishing a clinically relevant bioburden benchmark: A quality indicator for adequate reprocessing and storage of flexible gastrointestinal endoscopes. Am J Infect Control 2012; 40:233–236.

Alfano-Sobsey E, Sweat D, Hall A, Breedlove F, et al. Norovirus outbreak associated with undercooked oysters and secondary household transmission. Epidemiol Infect 2012; 140:276–282. View Full Text | PubMed | CrossRef

Alonso CD, Treadway SB, Hanna DB, Huff CA, et al. Epidemiology and Outcomes of Clostridium difficile Infections in Hematopoietic Stem Cell Transplant Recipients. Clin Infect Dis 2012; 54:1053–1063. View Full Text | PubMed | CrossRef

Baird-Howell MA, Wurzel J. Fatal gastrointestinal hemorrhage in a paraplegic man with undiagnosed AA (secondary) amyloidosis. Amyloid-J Protein Fold Disord 2011; 18:245–248.

Barlow R, Price P, Reid TD, Hunt S, et al. Prospective multicentre randomised controlled trial of early enteral nutrition for patients undergoing major upper gastrointestinal surgical resection. Clin Nutr 2011; 30:560–566. PubMed | CrossRef

Baumann-Popczyk A, Sadkowska-Todys M, Rogalska J, Stefanoff P. Incidence of self-reported acute gastrointestinal infections in the community in Poland: a population-based study. Epidemiol Infect 2012; 140:1173–1184. View Full Text | PubMed | CrossRef

Bertolazzi S, Lanzarotto F, Zanini B, Ricci C, et al. Bio-physical characteristics of gastrointestinal mucosa of celiac patients: comparison with control subjects and effect of gluten free diet- - art. no. 119. BMC Gastroenterol 2011; 11:7.

Bonnel AR, Bunchorntavakul C, Reddy KR. Immune Dysfunction and Infections in Patients With Cirrhosis. Clin Gastroenterol Hepatol 2011; 9:727–738. PubMed | CrossRef

Carvalho A, Giovannini G, De Luca A, D'Angelo C, et al. Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis. Cell Mol Immunol 2012; 9:276–286. PubMed

Cathcart MC, O'Byrne KJ, Reynolds JV, O'Sullivan J, et al. COX-derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention. Biochim Biophys Acta-Rev Cancer 2012; 1825:49–63. PubMed | CrossRef

Certad G, Benamrouz S, Guyot K, Mouray A, et al. Fulminant Cryptosporidiosis after Near-Drowning: a Human Cryptosporidium parvum Strain Implicated in Invasive Gastrointestinal Adenocarcinoma and Cholangiocarcinoma in an Experimental Model. Appl Environ Microbiol 2012; 78:1746–1751. PubMed | CrossRef

Chai FY, Jiffre D. Preoperative Hypoalbuminemia is an Independent Risk Factor for the Development of Surgical Site Infection Following Gastrointestinal Surgery. Ann Surg 2011; 254:665. View Full Text | PubMed | CrossRef

Charalampopoulos D, Rastall RA. Prebiotics in foods. Curr Opin Biotechnol 2012; 23:187–191. PubMed

Chen SC, Lee YT, Tsai SJ, Lai KC, et al. Clinical Outcomes and Prognostic Factors of Cancer Patients with Pyogenic Liver Abscess. J Gastrointest Surg 2011; 15:2036–2043. PubMed | CrossRef

Chen Y, Chen ZJ, Guo RY, Chen N, et al. Correlation between gastrointestinal fungi and varying degrees of chronic hepatitis B virus infection. Diagn Microbiol Infect Dis 2011; 70:492–498. PubMed | CrossRef

Choi WS, Kim MJ, Park DW, Son SW, et al. Clarithromycin and amikacin vs. clarithromycin and moxifloxacin for the treatment of post-acupuncture cutaneous infections due to Mycobacterium abscessus: a prospective observational study. Clin Microbiol Infect 2011; 17:1084–1090. View Full Text | PubMed | CrossRef

Chow J, Tang HQ, Mazmanian SK. Pathobionts of the gastrointestinal microbiota and inflammatory disease. Curr Opin Immunol 2011; 23:473–480. PubMed | CrossRef

Coban S, Soykan I, Toruner M, Akbulut H, et al. The effect of age and Helicobacter pylori infection on gastric epithelial cell kinetics. Clin Res Hepatol Gastroenterol 2011; 35:661–665.

Colwick SE, Alkhoury F, Martin JT, Ferneini AM. Abdominal Aortic Aneurysm Repair Complicated by Infection With Clostridium septicum - art. no. 839.e11. Ann Vasc Surg 2011; 25:E11. PubMed

de Smet A, Bonten MJM, Kluytmans J. For whom should we use selective decontamination of the digestive tract? Curr Opin Infect Dis 2012; 25:211–217.

Denton PW, Garcia JV. Humanized Mouse Models of HIV Infection. Aids Rev 2011; 13:135–148. PubMed

Deretzi G, Kountouras J, Polyzos SA, Zavos C, et al. Gastrointestinal Immune System and Brain Dialogue Implicated in Neuroinflammatory and Neurodegenerative Diseases. Curr Mol Med 2011; 11:696–707. PubMed | CrossRef

Dolatkhah R, Khoshbaten M, Kermani IA, Bonyadi MR, et al. Upper gastrointestinal bleedings in patients with hereditary coagulation disorders in Northwest of Iran: prevalence of Helicobacter pylori infection. Eur J Gastroenterol Hepatol 2011; 23:1172–1177. View Full Text | PubMed | CrossRef

Du Pont HL. Gastrointestinal infections and the development of irritable bowel syndrome. Curr Opin Infect Dis 2011; 24:503–508.

Ebert EC, Hagspiel KD. Gastrointestinal manifestations of leukemia. J Gastroenterol Hepatol 2012; 27:458–463. View Full Text | PubMed | CrossRef

El Hed A, Unutmaz D. Th17 cells and HIV infection. Curr Opin HIV AIDS 2010; 5:146–150.

Filler SG. Insights from human studies into the host defense against candidiasis. Cytokine 2012; 58:129–132. View Full Text | PubMed | CrossRef

Foster N, Elsheikha HM. The immune response to parasitic helminths of veterinary importance and its potential manipulation for future vaccine control strategies. Parasitol Res 2012; 110:1587–1599. PubMed | CrossRef

Fujitani K, Tsujinaka T, Fujita J, Miyashiro I, et al. Prospective randomized trial of preoperative enteral immunonutrition followed by elective total gastrectomy for gastric cancer. Br J Surg 2012; 99:621–629. View Full Text | PubMed | CrossRef

Fukuzawa M, Kawai T, Watanabe M, Tomiyama H, et al. Correlation between Helicobacter pylori infection and low-dose aspirin use on damage of the upper gastrointestinal tract. J Gastroenterol Hepatol 2012; 27:76–81. View Full Text | PubMed | CrossRef

Gowdy KM, Cardona DM, Nugent JL, Giamberardino C, et al. Novel Role for Surfactant Protein A in Gastrointestinal Graft-versus-Host Disease. J Immunol 2012; 188:4897–4905. PubMed | CrossRef

Grinberg A, Pomroy WE, Squires RA, Scuffham A, et al. Retrospective cohort study of an outbreak of cryptosporidiosis caused by a rare Cryptosporidium parvum subgenotype. Epidemiol Infect 2011; 139:1542–1550. View Full Text | PubMed | CrossRef

Hannu T. Reactive arthritis. Best Pract Res Clin Rheumatol 2011; 25:347–357. PubMed | CrossRef

Hao QK, Lu ZC, Dong BR, Huang CQ, et al. Probiotics for preventing acute upper respiratory tract infections - art. no. CD006895. Cochrane Database Syst Rev 2011; 6895.

Hennessey D, Burke JP, Winter DC, Mealy K. Is Preoperative Serum Albumin Enough to Ensure Nutritional Status in the Development of Surgical Site Infection Following Gastrointestinal Surgery? Reply. Ann Surg 2011; 254:664. View Full Text | PubMed | CrossRef

Hennessey D, Burke JP, Winter DC, Mealy K. Preoperative Hypoalbuminemia is an Independent Risk Factor for the Development of Surgical Site Infection Following Gastrointestinal Surgery Reply. Ann Surg 2011; 254:665–666. View Full Text | PubMed | CrossRef

Israeli E, Agmon-Levin N, Blank M, Chapman J, et al. Guillain-Barre Syndrome-A Classical Autoimmune Disease Triggered by Infection or Vaccination. Clin Rev Allergy Immunol 2012; 42:121–130. View Full Text | PubMed | CrossRef

Jara S, Sanchez M, Vera R, Cofre J, et al. The inhibitory activity of Lactobacillus spp. isolated from breast milk on gastrointestinal pathogenic bacteria of nosocomial origin. Anaerobe 2011; 17:474–477. PubMed | CrossRef

Kaimi I, Diggle PJ. A hierarchical model for real-time monitoring of variation in risk of non-specific gastrointestinal infections. Epidemiol Infect 2011; 139:1854–1862. View Full Text | PubMed | CrossRef

Kaufman DR, De Calisto J, Simmons NL, Cruz AN, et al. Vitamin A Deficiency Impairs Vaccine-Elicited Gastrointestinal Immunity. J Immunol 2011; 187:1877–1883. PubMed | CrossRef

Khameneh ZR, Sepehrvand N, Hatami S, Afshari AT. The Seroprevalence of Helicobacter pylori Infection in Renal Transplant Recipients. Transplant Proc 2011; 43:3720–3722. PubMed | CrossRef

Ki ELL, Chan FKL. Interaction of Helicobacter pylori infection and low-dose aspirin in the upper gastrointestinal tract: Implications for clinical practice. Best Pract Res Clin Gastroenterol 2012; 26:163–172.

Kim YJ, Kim EH, Hahm KB. Oxidative stress in inflammation-based gastrointestinal tract diseases: Challenges and opportunities. J Gastroenterol Hepatol 2012; 27:1004–1010.

Klatt NR, Brenchley JM. Th17 cell dynamics in HIV infection. Curr Opin HIV AIDS 2010; 5:135–140.

Kwa S, Kannanganat S, Nigam P, Siddiqui M, et al. Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques. Blood 2011; 118:2763–2773. PubMed | CrossRef

Lempinen M, Halme L, Arola J, Honkanen E, et al. HHV-6B is frequently found in the gastrointestinal tract in kidney transplantation patients. Transpl Int 2012; 25:776–782. View Full Text | PubMed | CrossRef

Littman DR, Pamer EG. Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses. Cell Host Microbe 2011; 10:311–323. PubMed | CrossRef

Liu XY, Wu SP, Xia YL, Li XE, et al. Wingless homolog Wnt11 suppresses bacterial invasion and inflammation in intestinal epithelial cells. Am J Physiol-Gastroint Liver Physiol 2011; 301:G992–G1003.

Lu PH, Wei MX, Shen W, Li C, et al. Is Preoperative Serum Albumin Enough to Ensure Nutritional Status in the Development of Surgical Site Infection Following Gastrointestinal Surgery? Ann Surg 2011; 254:663–664.

Lye DJ. Gastrointestinal Colonization Rates for Human Clinical Isolates of Aeromonas Veronii Using a Mouse Model. Curr Microbiol 2011; 63:332–336. PubMed | CrossRef

Mann EA, Saeed SA. Gastrointestinal infection as a trigger for inflammatory bowel disease. Curr Opin Gastroenterol 2012; 28:24–29. View Full Text | PubMed | CrossRef

Mascarello M, Gobbi F, Angheben A, Gobbo M, et al. Prevalence of Strongyloides stercoralis infection among HIV-positive immigrants attending two Italian hospitals, from 2000 to 2009. Ann Trop Med Parasitol 2011; 105:617–623. PubMed | CrossRef

McCarthy DM. Efficacy and gastrointestinal risk of aspirin used for the treatment of pain and cold. Best Pract Res Clin Gastroenterol 2012; 26:101–112. PubMed | CrossRef

Mikko S. Interactions of alcohol and tobacco in gastrointestinal cancer. J Gastroenterol Hepatol 2012; 27:135–139.

Milner JD, Sandler NG, Douek DC. Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections. Curr Opin HIV AIDS 2010; 5:179–183. View Full Text | PubMed

Miyagaki H, Nakajima K, Hara J, Yamasaki M, et al. Performance comparison of peripherally inserted central venous catheters in gastrointestinal surgery: A randomized controlled trial. Clin Nutr 2012; 31:48–52. PubMed | CrossRef

Moberg C, Naesdal J, Svedberg LE, Duchateau D, et al. Impact of Gastrointestinal Problems on Adherence to Low-Dose Acetylsalicylic Acid A Quantitative Study in Patients with Cardiovascular Risk. Patient 2011; 4:103–113. View Full Text | PubMed

Morrow LE, Gogineni V, Malesker MA. Probiotic, prebiotic, and synbiotic use in critically ill patients. Curr Opin Crit Care 2012; 18:186–191. View Full Text | PubMed | CrossRef

Naf F, Warschkow R, Kolb W, Zund M, et al. Selective decontamination of the gastrointestinal tract in patients undergoing esophageal resection - art. no. 36. BMC Surg 2010; 10:16.

Nagata N, Iizuka T, Oka S. Gastrointestinal: Kaposi's sarcoma coexistent with Cytomegalovirus (CMV) infection. J Gastroenterol Hepatol 2011; 26:1340. View Full Text | PubMed | CrossRef

Navaneethan U, Venkatesh PGK, Downs-Kelly E, Shen B. Isospora belli superinfection in a patient with eosinophilic gastroenteritis-A diagnostic challenge. J Crohns Colitis 2012; 6:236–239. PubMed

Navaneethan U, Venkatesh PGK, Wang J. Cytomegalovirus ileitis in a patient after liver transplantation-differentiating from de novo IBD. J Crohns Colitis 2011; 5:354–359. PubMed

Neil KP, Biggerstaff G, MacDonald JK, Trees E, et al. A Novel Vehicle for Transmission of Escherichia coli O157:H7 to Humans: Multistate Outbreak of E. coli O157:H7 Infections Associated With Consumption of Ready-to-Bake Commercial Prepackaged Cookie Dough-United States, 2009. Clin Infect Dis 2012; 54:511–518. View Full Text | PubMed | CrossRef

Nishiura H, Kido M, Aoki N, Iwamoto S, et al. Increased Susceptibility to Autoimmune Gastritis in Thymic Stromal Lymphopoietin Receptor-Deficient Mice. J Immunol 2012; 188:190–197. PubMed | CrossRef

Nseir W, Mograbi J, Di Castro N, Abu-Elheja O, et al. On the Association Between Soft Drink Consumption and Helicobacter pylori Infection. Dig Dis Sci 2012; 57:981–986. View Full Text | PubMed | CrossRef

Ofek-Shlomai N, Benenson S, Ergaz Z, Peleg O, et al. Gastrointestinal colonization with ESBL-producing Klebsiella in preterm babies-is vancomycin to blame? Eur J Clin Microbiol Infect Dis 2012; 31:567–570.

Origasa H, Goto S, Shimada K, Uchiyama S, et al. Prospective Cohort Study of Gastrointestinal Complications and Vascular Diseases in Patients Taking Aspirin: Rationale and Design of the MAGIC Study. Cardiovasc Drugs Ther 2011; 25:551–560. View Full Text | PubMed | CrossRef

Paiardini M. Th17 cells in natural SIV hosts. Curr Opin HIV AIDS 2010; 5:166–172. View Full Text | PubMed

Partridge DG, Evans CM, Raza M, Kudesia G, et al. Lessons from a large norovirus outbreak: impact of viral load, patient age and ward design on duration of symptoms and shedding and likelihood of transmission. J Hosp Infect 2012; 81:25–30. PubMed | CrossRef

Porter CK, Gloor K, Cash BD, Riddle MS. Risk of Functional Gastrointestinal Disorders in U.S. Military Following Self-Reported Diarrhea and Vomiting During Deployment. Dig Dis Sci 2011; 56:3262–3269. View Full Text | PubMed | CrossRef

Quach C, McArthur M, McGeer A, Li L, et al. Risk of infection following a visit to the emergency department: a cohort study. Can Med Assoc J 2012; 184:412. PubMed

Ruiz P. How can pathologists help to diagnose late complications in small bowel and multivisceral transplantation? Curr Opin Organ Transpl 2012; 17:273–279.

Schiff MH, Kremer JM, Jahreis A, Vernon E, et al. Integrated safety in tocilizumab clinical trials - art. no. R141. Arthritis Res Ther 2011; 13:R141. PubMed | CrossRef

Shiotani A, Manabe N, Kamada T, Fujimura Y, et al. Risk and preventive factors of low-dose aspirin-induced gastroduodenal injuries: A comprehensive review. J Gastroenterol Hepatol 2012; 27:8–12. View Full Text | PubMed | CrossRef

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 1: Bacterial, viral and fungal infections. Clin Radiol 2012; 67:484–494. PubMed

Sinha R, Rajesh A, Rawat S, Rajiah P, et al. Infections and infestations of the gastrointestinal tract. Part 2: Parasitic and other infections. Clin Radiol 2012; 67:495–504. PubMed

Slavik T. Human Immunodeficiency Virus-Related Gastrointestinal Pathology A Southern Africa Perspective With Review of the Literature (Part 1: Infections). Arch Pathol Lab Med 2012; 136:305–315. PubMed | CrossRef

Slavik T. Human Immunodeficiency Virus-Related Gastrointestinal Pathology A Southern Africa Perspective With Review of the Literature (Part 2: Neoplasms and Noninfectious Disorders). Arch Pathol Lab Med 2012; 136:316–323. PubMed | CrossRef

Sofat S, Pope NH, David EA, Bhanot P. Successful Application of the Vacuum-Assisted Closure System in Delayed Primary Closure: A Case of Gastrointestinal Perforation. Am Surg 2011; 77:E168–E169. PubMed

Sood P, Kumar G, Nanchal R, Sakhuja A, et al. Chronic Kidney Disease and End-Stage Renal Disease Predict Higher Risk of Mortality in Patients with Primary Upper Gastrointestinal Bleeding. Am J Nephrol 2012; 35:216–224. PubMed | CrossRef

Spitzer D, Schuff M, Zintz M, Murtinger M, et al. Possible deleterious impact of putative gastrointestinal infections in the time period of oocyte recruitment on fertilization after IMSI: Two case reports of consecutive IVF attempts. J Assist Reprod Genet 2012; 29:429–431. View Full Text | PubMed | CrossRef

Stackhouse RR, Faith NG, Kaspar CW, Czuprynski CJ, et al. Survival and Virulence of Salmonella enterica Serovar Enteritidis Filaments Induced by Reduced Water Activity. Appl Environ Microbiol 2012; 78:2213–2220. PubMed | CrossRef

Struijk M, Postma DF, van Tuyl SAC, van de Ree MA. Optimal drug therapy after aspirin-induced upper gastrointestinal bleeding. Eur J Intern Med 2012; 23:227–230. PubMed | CrossRef

Su CY, Pei J, Lu XH, Tang W, et al. Gastrointestinal symptoms predict peritonitis rates in CAPD patients. Clin Nephrol 2012; 77:267–274. PubMed | CrossRef

Sugimoto M, Ohno T, Graham DY, Yamaoka Y. Helicobacter pylori outer membrane proteins on gastric mucosal interleukin 6 and 11 expression in Mongolian gerbils. J Gastroenterol Hepatol 2011; 26:1677–1684. View Full Text | PubMed | CrossRef

Thomas LV, Ockhuizen T. New insights into the impact of the intestinal microbiota on health and disease: a symposium report. Br J Nutr 2012; 107:S1–S13. PubMed | CrossRef

Valkhoff VE, Sturkenboom M, Kuipers EJ. Risk factors for gastrointestinal bleeding associated with low-dose aspirin. Best Pract Res Clin Gastroenterol 2012; 26:125–140. PubMed | CrossRef

van de Ven A, van Konijnenburg DPH, Wensing AMJ, van Montfrans JM. The Role of Prolonged Viral Gastrointestinal Infections in the Development of Immunodeficiency-Related Enteropathy. Clin Rev Allergy Immunol 2012; 42:79–91. View Full Text | PubMed | CrossRef

Verweij JJ, Van Lieshout L. Intestinal parasitic infections in an industrialized country; a new focus on children with better DNA-based diagnostics. Parasitology 2011; 138:1492–1498. View Full Text | PubMed | CrossRef

Vikram HR, Smilack JD, Leighton JA, Crowell MD, et al. Emergence of Gastrointestinal Basidiobolomycosis in the United States, With a Review of Worldwide Cases. Clin Infect Dis 2012; 54:1685–1691.

Walravens J, Brouwers J, Spriet I, Tack J, et al. Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole Monitoring of Intraluminal and Plasma Drug Concentrations. Clin Pharmacokinet 2011; 50:725–734. View Full Text | PubMed | CrossRef

Wang HE, Gamboa C, Warnock DG, Muntner P. Chronic Kidney Disease and Risk of Death from Infection. Am J Nephrol 2011; 34:330–336. PubMed | CrossRef

Wong CCM, Zhang L, Ren SX, Shen J, et al. Antibacterial Peptides and Gastrointestinal Diseases. Curr Pharm Design 2011; 17:1583–1586.

Yip T, Tse KC, Ng F, Hung I, et al. Clinical course and outcomes of single-organism enterococcus peritonitis in peritoneal dialysis patients. Perit Dial Int 2011; 31:522–528. PubMed | CrossRef

Back to Top | Article Outline
Implication of gastrointestinal infection

Agaimy A, Mudter J, Markl B, Chetty R. Cytomegalovirus infection presenting as isolated inflammatory polyps of the gastrointestinal tract. Pathology 2011; 43:440–446. View Full Text | PubMed | CrossRef

Annunziata ML, Caviglia R, Papparella LG, Cicala M. Upper Gastrointestinal Involvement of Crohn's Disease: A Prospective Study on the Role of Upper Endoscopy in the Diagnostic Work-Up. Dig Dis Sci 2012; 57:1618–1623. View Full Text | PubMed | CrossRef

Cheng HY, Zhang T, Gu WZ, Shu XL, et al. The Presence of Helicobacter pylori in Colorectal Polyps Detected by Immunohistochemical Methods in Children. Pediatr Infect Dis J 2012; 31:364–367. View Full Text | PubMed | CrossRef

Coban S, Soykan I, Toruner M, Akbulut H, et al. The effect of age and Helicobacter pylori infection on gastric epithelial cell kinetics. Clin Res Hepatol Gastroenterol 2011; 35:661–665.

Colwick SE, Alkhoury F, Martin JT, Ferneini AM. Abdominal Aortic Aneurysm Repair Complicated by Infection With Clostridium septicum - art. no. 839.e11. Ann Vasc Surg 2011; 25:E11. PubMed

Fairley RA, Pesavento PA, Clark RG. Listeria monocytogenes Infection of the Alimentary Tract (Enteric Listeriosis) of Sheep in New Zealand. J Comp Pathol 2012; 146:308–313. PubMed | CrossRef

Israeli E, Agmon-Levin N, Blank M, Chapman J, et al. Guillain-Barre Syndrome-A Classical Autoimmune Disease Triggered by Infection or Vaccination. Clin Rev Allergy Immunol 2012; 42:121–130. View Full Text | PubMed | CrossRef

Jara S, Sanchez M, Vera R, Cofre J, et al. The inhibitory activity of Lactobacillus spp. isolated from breast milk on gastrointestinal pathogenic bacteria of nosocomial origin. Anaerobe 2011; 17:474–477. PubMed | CrossRef

Liu ZP, Zaki MH, Vogel P, Gurung P, et al. Role of Inflammasomes in Host Defense against Citrobacter rodentium Infection. J Biol Chem 2012; 287:16955–16964. PubMed | CrossRef

Lukyanenko V, Malyukova I, Hubbard A, De lannoy M, et al. Enterohemorrhagic Escherichia coli infection stimulates Shiga toxin 1 macropinocytosis and transcytosis across intestinal epithelial cells. Am J Physiol-Cell Physiol 2011; 301:C1140–C1149. PubMed | CrossRef

O'Shea EF, O'Connor PM, Raftis EJ, O'Toole PW, et al. Production of Multiple Bacteriocins from a Single Locus by Gastrointestinal Strains of Lactobacillus salivarius. J Bacteriol 2011; 193:6973–6982. PubMed | CrossRef

Oshima H, Oshima M. The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models. J Gastroenterol 2012; 47:97–106. PubMed | CrossRef

Permpoonpattana P, Tolls EH, Nadem R, Tan S, et al. Surface Layers of Clostridium difficile Endospores. J Bacteriol 2011; 193:6461–6470. PubMed | CrossRef

Rumio C, Sommariva M, Sfondrini L, Palazzo M, et al. Induction of Paneth cell degranulation by orally administered Toll-like receptor ligands. J Cell Physiol 2012; 227:1107–1113. PubMed | CrossRef

Sofat S, Pope NH, David EA, Bhanot P. Successful Application of the Vacuum-Assisted Closure System in Delayed Primary Closure: A Case of Gastrointestinal Perforation. Am Surg 2011; 77:E168–E169. PubMed

Stevens DL, Aldape MJ, Bryant AE. Life-threatening clostridial infections. Anaerobe 2012; 18:254–259.

van de Ven A, van Konijnenburg DPH, Wensing AMJ, van Montfrans JM. The Role of Prolonged Viral Gastrointestinal Infections in the Development of Immunodeficiency-Related Enteropathy. Clin Rev Allergy Immunol 2012; 42:79–91. View Full Text | PubMed | CrossRef

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Large intestine
Important clinical advances in the understanding of Clostridium difficile infection

Review: (pp. 42–48)

Al-Moubarak E, Simons C. A homology model for Clostridium difficile methionyl tRNA synthetase: active site analysis and docking interactions. J Mol Model 2011; 17:1679–1693. PubMed | CrossRef

Alcaraz I, Cerroni L, Rutten A, Kutzner H, et al. Cutaneous Metastases From Internal Malignancies: A Clinicopathologic and Immunohistochemical Review. Am J Dermatopathol 2012; 34:347–390. View Full Text | PubMed | CrossRef

▪. Alonso CD, Treadway SB, Hanna DB, et al. Epidemiology and outcomes of Clostridium difficile infections in hematopoietic stem cell transplant recipients. Clin Infect Dis 2012; 54:1053–1063. [14]

Ammam F, Marvaud JC, Lambert T. Distribution of the vanG-like gene cluster in Clostridium difficile clinical isolates. Can J Microbiol 2012; 58:547–551. PubMed

Ananthakrishnan AN, Binion DG. Impact of Clostridium difficile on inflammatory bowel disease. Expert Rev Gastroenterol Hepatol 2010; 4:589–600. View Full Text | PubMed | CrossRef

Armbruster S, Goldkind L. A 5-Year Retrospective Review of Experience With Clostridium difficile-Associated Diarrhea. Milit Med 2012; 177:456–459. PubMed | CrossRef

Bakken JS, Borody T, Brandt LJ, Brill JV, et al. Treating Clostridium difficile Infection With Fecal Microbiota Transplantation. Clin Gastroenterol Hepatol 2011; 9:1044–1049. PubMed | CrossRef

▪. Bakken JS, Borody T, Brandt LJ, et al. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol Hepatol 2011; 9:1044–1049. [43]

Barbut F, Jones G, Eckert C. Epidemiology and control of Clostridium difficile infections in healthcare settings: an update. Curr Opin Infect Dis 2011; 24:370–376. View Full Text | PubMed

Bertolo L, Boncheff AG, Ma ZC, Chen YH, et al. Clostridium difficile carbohydrates: glucan in spores, PSII common antigen in cells, immunogenicity of PSII in swine and synthesis of a dual C. difficile-ETEC conjugate vaccine. Carbohydr Res 2012; 354:79–86. PubMed | CrossRef

▪. Black SR, Weaver KN, Jones RC, et al. Clostridium difficile outbreak strain BI is highly endemic in Chicago area hospitals. Infect Control Hosp Epidemiol 2011; 32:897–902. [04]

▪. Boyanton Jr BL, Sural P, Loomis CR, et al. Loop-mediated isothermal amplification compared to real-time PCR and enzyme immunoassay for toxigenic Clostridium difficile detection. J Clin Microbiol 2012; 50:640–645. [31]

▪. Brandt LJ, Aroniadis OC, Mellow M, et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection. Am J Gastroenterol 2012; 107:1079–1087. [40]

Brazier JS. Clostridium difficile: The anaerobe that made the grade. Anaerobe 2012; 18:197–199. PubMed | CrossRef

Burns DA, Minton NP. Sporulation studies in Clostridium difficile. J Microbiol Methods 2011; 87:133–138. PubMed | CrossRef

Carasi P, Trejo FM, Perez PF, De Antoni GL, et al. Surface proteins from Lactobacillus kefir antagonize in vitro cytotoxic effect of Clostridium difficile toxins. Anaerobe 2012; 18:135–142. PubMed | CrossRef

Carman RJ, Stevens AL, Lyerly MW, Hiltonsmith MF, et al. Clostridium difficile binary toxin (CDT) and diarrhea. Anaerobe 2011; 17:161–165. PubMed | CrossRef

Carroll KC. Tests for the diagnosis of Clostridium difficile infection: The next generation. Anaerobe 2011; 17:170–174. PubMed | CrossRef

Choi HK, Kim KH, Lee SH, Lee SJ. Risk Factors for Recurrence of Clostridium difficile Infection: Effect of Vancomycin-resistant Enterococci Colonization. J Korean Med Sci 2011; 26:859–864. PubMed | CrossRef

Citron DM, Tyrrell KL, Merriam CV, Goldstein EJC. In Vitro Activities of CB-183,315, Vancomycin, and Metronidazole against 556 Strains of Clostridium difficile, 445 Other Intestinal Anaerobes, and 56 Enterobacteriaceae Species. Antimicrob Agents Chemother 2012; 56:1613–1615. PubMed | CrossRef

Collini PJ, Bauer M, Kuijper E, Dockrell DH. Clostridium difficile infection in HIV-seropositive individuals and transplant recipients. J Infect 2012; 64:131–147. PubMed | CrossRef

▪▪. Cornely OA, Crook DW, Esposito R, et al. Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, noninferiority, randomized controlled trial. Lancet Infect Dis 2012; 12:281–289. [35]

Cornely OA, Crook DW, Esposito R, Poirier A, et al. Fidaxomicin versus vancomycin for infection with Clostridium difficile in Europe, Canada, and the USA: a double-blind, non-inferiority, randomised controlled trial. Lancet Infect Dis 2012; 12:281–289.

Crawford T, Huesgen E, Danziger L. Fidaxomicin: A novel macrocyclic antibiotic for the treatment of Clostridium difficile infection. Am J Health-Syst Pharm 2012; 69:933–943. View Full Text | PubMed | CrossRef

Dang THT, Fagan RP, Fairweather NF, Tate EW. Novel inhibitors of surface layer processing in Clostridium difficile. Bioorg Med Chem 2012; 20:614–621. PubMed | CrossRef

Davies AH, Roberts AK, Shone CC, Acharya KR. Super toxins from a super bug: structure and function of Clostridium difficile toxins. Biochem J 2011; 436:517–526. PubMed

▪. Deshpande A, Pasupuleti V, Rolston DDK, et al. Diagnostic accuracy of real-time polymerase chain reaction in detection of Clostridium difficile in the stool samples of patients with suspected Clostridium difficile infection: a meta-analysis. Clin Infect Dis 2011; 53:e81–e90. [28]

Drekonja DM, Amundson WH, De Carolis DD, Kuskowski MA, et al. Antimicrobial Use and Risk for Recurrent Clostridium difficile Infection - art. no. e1. Am J Med 2011; 124:E1. PubMed

▪. Drekonja DM, Amundson WH, De Carolis DD, et al. Antimicrobial use and risk for recurrent Clostridium difficile infection. Am J Med 2011; 124:1081.e1–1081.e7. [18]

▪. Dubberke ER, Han Z, Bobo L, et al. Impact of clinical symptoms on interpretation of diagnostic assays for Clostridium difficile infections. J Clin Microbiol 2011; 49:2887–2893. [33]

Enoch DA, Butler MJ, Pai S, Aliyu SH, et al. Clostridium difficile in children: Colonisation and disease. J Infect 2011; 63:105–113. PubMed | CrossRef

Freifeld AG, Simonsen KA, Booth CS, Zhao X, et al. A New Rapid Method for Clostridium difficile DNA Extraction and Detection in Stool Toward Point-of-Care Diagnostic Testing. J Mol Diagn 2012; 14:274–279. PubMed | CrossRef

▪. Garey KW, Ghantoji SS, Shah DN, et al. A randomized, double-blind, placebo-controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection. J Antimicrob Chemother 2011; 66:2850–2855. [37]

▪. Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis 2011; 53:994–1002. [39]

Govind R, Fralick JA, Rolfe RD. In vivo lysogenization of a Clostridium difficile bacteriophage Phi CD119. Anaerobe 2011; 17:125–129.

Grando D, Said MM, Mayall BC, Gurtler V. High resolution melt analysis to track infections due to ribotype 027 Clostridium difficile. J Microbiol Methods 2012; 89:87–94. PubMed | CrossRef

▪. Greenberg RN, Marbury TC, Foglia G, Warny M. Phase I dose finding studies of an adjuvanted Clostridium difficile toxoid vaccine. Vaccine 2012; 30:2245–2249. [50]

Guarino A, Wudy A, Basile F, Ruberto E, et al. Composition and roles of intestinal microbiota in children. J Matern-Fetal Neonatal Med 2012; 25:63–66. PubMed | CrossRef

Gueimonde M, Collado MC. Metagenomics and probiotics. Clin Microbiol Infect 2012; 18:32–34. View Full Text | PubMed | CrossRef

▪. Hall AJ, Curns AT, McDonald LC, et al. The roles of Clostridium difficile and Norovirus among gastroenteritis-associated deaths in the United States, 1999–2007. Clin Infect Dis 2012; 55:216–223. [13]

Han ZL, McMullen KM, Russo AJ, Copper SM, et al. A Clostridium difficile infection “intervention”: Change in toxin assay results in fewer C difficile infection cases without changes in patient outcomes. Am J Infect Control 2012; 40:349–353. View Full Text | PubMed | CrossRef

▪. Janarthanan S, Ditah I, Adler DG, Ehrinpreis MN. Clostridium difficile-associated diarrhea and proton pump inhibitor therapy: a meta-analysis. Am J Gastroenterol 2012; 107:1001–1010. [24]

▪. Johnson S, Gerding DN, Louie TJ, et al. Sustained clinical response as an endpoint in treatment trials of Clostridium difficile-associated diarrhea. Antimicrob Agents Chemother 2012; 56:4043–4045. [36]

▪. Kasper AM, Nyazee HA, Yokoe DS, et al. A multicenter study of Clostridium difficile infection-related colectomy, 2000–2006. Infect Control Hosp Epidemiol 2012; 33:470–476. [12]

▪. Kassam Z, Hundal R, Marshall JK, Lee CH. Fecal transplant via retention enema for refractory or recurrent Clostridium difficile infection. Arch Intern Med 2012; 172:191–193. [42]

Kawada M, Annaka M, Kato H, Shibasaki S, et al. Evaluation of a simultaneous detection kit for the glutamate dehydrogenase antigen and toxin A/B in feces for diagnosis of Clostridium difficile infection. J Infect Chemother 2011; 17:807–811. PubMed | CrossRef

Kee VR. Clostridium Difficile Infection in Older Adults: A Review and Update on Its Management. Am J Geriatr Pharmacother 2012; 10:14–24. PubMed | CrossRef

▪. Kelly CR, de Leon L, Jasutkar N. Fecal microbiota transplantation for relapsing Clostridium difficile infection in 26 patients. Methodology and results. J Clin Gastroenterol 2012; 46:145–149. [41]

▪. Khanna S, Pardi DS, Rosenblatt JE, et al. An evaluation of repeat stool testing for Clostridium difficile infection by polymerase chain reaction. J Clin Gastroenterol 2012. [Epub ahead of print] [32]

Khanna S, Pardi DS. IBD Poor outcomes after Clostridium difficile infection in IBD. Nat Rev Gastroenterol Hepatol 2012; 9:307–308. View Full Text | PubMed | CrossRef

Khanna S, Pardi DS. The growing incidence and severity of Clostridium difficile infection in inpatient and outpatient settings. Expert Rev Gastroenterol Hepatol 2010; 4:409–416. View Full Text | PubMed | CrossRef

Kim J, Pai H, Seo MR, Kang JO. Epidemiology and Clinical Characteristics of Clostridium difficile Infection in a Korean Tertiary Hospital. J Korean Med Sci 2011; 26:1258–1264. PubMed | CrossRef

Kotila SM, Virolainen A, Snellman M, Ibrahem S, et al. Incidence, case fatality and genotypes causing Clostridium difficile infections, Finland, 2008. Clin Microbiol Infect 2011; 17:888–893. View Full Text | PubMed | CrossRef

La Marche MJ, Leeds JA, Amaral A, Brewer JT, et al. Discovery of LFF571: An Investigational Agent for Clostridium difficile Infection. J Med Chem 2012; 55:2376–2387. PubMed

La Sala PR, Svensson AM, Mohammad AA, Perrotta PL. Comparison of Analytical and Clinical Performance of Three Methods for Detection of Clostridium difficile. Arch Pathol Lab Med 2012; 136:527–531. PubMed

▪. Lalande V, Barrault L, Wadel S, et al. Evaluation of a loop-mediated isothermal amplification assay for diagnosis of Clostridium difficile infections. J Clin Microbiol 2011; 49:2714–2716. [30]

Lancaster JW, Matthews SJ. Fidaxomicin: The Newest Addition to the Armamentarium Against Clostridium difficile Infections. Clin Ther 2012; 34:1–13. PubMed | CrossRef

Larson KC, Belliveau PP, Spooner LM. Tigecycline for the Treatment of Severe Clostridium difficile Infection. Ann Pharmacother 2011; 45:1005–1010. PubMed | CrossRef

Lo Vecchio A, Zacur GM. Clostridium difficile infection: an update on epidemiology, risk factors, and therapeutic options. Curr Opin Gastroenterol 2012; 28:1–9. View Full Text | PubMed | CrossRef

▪. Loo VG, Bourgault A-M, Poirier L, et al. Host and pathogen factors for Clostridium difficile infection and colonization. N Engl J Med 2011; 365:1693–1703. [03]

▪▪. Louie TJ, Miller MA, Mullane KM, et al. Fidaxomicin versus vancomycin for Clostridium difficile infection. N Engl J Med 2011; 364:422–431. [34]

▪. Lucado J, Gould C, Elixhauser A. Clostridium difficile infections (CDI) in hospital stays, 2009. HCUP Statistical Brief #124. January 2012. Rockville, MD: Agency for Healthcare Research and Quality. http://http://www.hcup-us.ahrq.gov/reports/statbriefs/sb124.pdf. [08]

Manek K, Williams V, Callery S, Daneman N. Reducing the risk of severe complications among patients with Clostridium difficile infection. Can J Gastroenterol 2011; 25:368–372. PubMed

McCollum DL, Rodriguez JM. Detection, Treatment, and Prevention of Clostridium difficile Infection. Clin Gastroenterol Hepatol 2012; 10:581–592. PubMed | CrossRef

▪▪. McDonald LC, Lessa F, Sievert D, et al. Vital signs: preventing Clostridium difficile infections. MMWR Morb Mortal Wkly Rep 2012; 61:1–6. [11]

McFarland LV. Emerging therapies for Clostridium difficile infections. Expert Opin Emerg Drugs 2011; 16:425–439. PubMed | CrossRef

Monge D, Morosini M, Milian I, Canosa CP, et al. Risk factors for Clostridium difficile infections in hospitalized patients. Med Clin 2011 Nov 2011; 137:575–580.

Mora AL, Salazar M, Pablo-Caeiro J, Frost CP, et al. Moderate to High Use of Opioid Analgesics Are Associated With an Increased Risk of Clostridium difficile Infection. Am J Med Sci 2012; 343:277–280. View Full Text | PubMed | CrossRef

Morris WE, Dunleavy MV, Diodati J, Berra G, et al. Effects of Clostridium perfringens alpha and epsilon toxins in the bovine gut. Anaerobe 2012; 18:143–147. PubMed | CrossRef

▪▪. Mullane KM, Miller MA, Weiss K, et al. Efficacy of fidaxomicin versus vancomycin as therapy for Clostridium difficile infection in individuals taking concomitant antibiotics for other concurrent infections. Clin Infect Dis 2011; 53:440–447. [17]

▪. Naggie S, Miller BA, Zuzak KB, et al. A case-control study of community-associated Clostridium difficile infection: no role for proton pump inhibitors. Am J Med 2011; 124:276.e1–276.e7. [22]

▪▪. Neal MD, Alverdy JC, Hall DE, et al. Diverting loop ileostomy and colonic lavage. An alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile-associated disease. Ann Surg 2011; 254:423–429. [45]

Nelson RL, Kelsey P, Leeman H, Meardon N, et al. Antibiotic treatment for Clostridium difficile-associated diarrhea in adults - art. no. CD004610. Cochrane Database Syst Rev 2011; 4610.

Nguyen GC. Bugs and Drugs: Insights into the Pathogenesis of Inflammatory Bowel Disease. Am J Gastroenterol 2011; 106:2143–2145. PubMed | CrossRef

▪. O'Horo JC, Jones A, Sternke M, et al. Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis. Mayo Clin Proc 2012; 87:643–651. [29]

Olling A, Seehase S, Minton NP, Tatge H, et al. Release of TcdA and TcdB from Clostridium difficile cdi 630 is not affected by functional inactivation of the tcdE gene. Microb Pathog 2012; 52:92–100. PubMed | CrossRef

Pant C, Deshpande A, Anderson MP, Sferra TJ. Clostridium difficile Infection Is Associated With Poor Outcomes in End-Stage Renal Disease. J Invest Med 2012; 60:529–532. View Full Text | PubMed

▪. Papatheodorou P, Carette JE, Bell GW, et al. Lipolysis-stimulated lipoprotein receptor (LSR) is the host receptor for the binary toxin Clostridium difficile transferase (CDT). Proc Natl Acad Sci U S A 2011; 108:16422–16427. [07]

Pepin J, Gonzales M, Valiquette L. Risk of secondary cases of Clostridium difficile infection among household contacts of index cases. J Infect 2012; 64:387–390. PubMed

Peterson LR, Mehta MS, Patel PA, Hacek DM, et al. Laboratory Testing for Clostridium difficile Infection Light at the End of the Tunnel. Am J Clin Pathol 2011; 136:372–380. PubMed | CrossRef

▪▪. Petrella LA, Sambol SP, Cheknis A, et al. Decreased cure and increased recurrence rates for Clostridium difficile infection caused by the epidemic C. difficile BI strain. Clin Infect Dis 2012; 55:351–357. [05]

Phillips ST, Nagaro K, Sambol SP, Johnson S, et al. Susceptibility of hamsters to infection by historic and epidemic BI Clostridium difficile strains during daily administration of three fluoroquinolones. Anaerobe 2011; 17:166–169. PubMed | CrossRef

Rebeaud F, Bachmann MF. Immunization strategies for Clostridium difficile infections. Expert Rev Vaccines 2012; 11:469–479. View Full Text | PubMed | CrossRef

Reid CW, Vinogradov E, Li JJ, Jarrell HC, et al. Structural characterization of surface glycans from Clostridium difficile. Carbohydr Res 2012; 354:65–73. PubMed | CrossRef

Shah K, Pass LA, Cox M, Lanham M, et al. Evaluating contemporary antibiotics as a risk factor for Clostridium difficile infection in surgical trauma patients. J Trauma Acute Care Surg 2012; 72:691–695.

▪. Shing Kwok C, Kobina Arthur A, Ifeanyichukwu Anibueze C, et al. Risk of Clostridium difficile infection with acid suppressing drugs and antibiotics: meta-analysis. Am J Gastroenterol 2012; 107:1011–1019. [23]

Svensson AM, La Sala PR. Pathology Consultation on Detection of Clostridium difficile. Am J Clin Pathol 2012; 137:10–15. PubMed | CrossRef

▪. Tian J-H, Fuhrmann SR, Kluepfel-Stahl S, et al. A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models. Vaccine 2012; 30:4249–4258. [51]

Tian Y, Huang TX, Li GC, Liu J, et al. Apoptosis of CT26 colorectal cancer cells induced by Clostridium difficile toxin A stimulates potent anti-tumor immunity. Biochem Biophys Res Commun 2012; 422:15–21. PubMed | CrossRef

Whitman CB, Czosnowski QA. Fidaxomicin for the Treatment of Clostridium difficile infections. Ann Pharmacother 2012; 46:219–228. PubMed | CrossRef

Back to Top | Article Outline
The colonic microbiota in health and disease

Review: (pp. 49–54)

Ahn J, Chen CY, Hayes RB. Oral microbiome and oral and gastrointestinal cancer risk. Cancer Causes Control 2012; 23:399–404. PubMed | CrossRef

Alcaraz LD, Belda-Ferre P, Cabrera-Rubio R, Romero H, et al. Identifying a healthy oral microbiome through metagenomics. Clin Microbiol Infect 2012; 18:54–57. View Full Text | PubMed | CrossRef

▪. Arumugam M, Raes J, Pelletier E, et al. Enterotypes of the human gut microbiome. Nature 2011; 473:174–180. [33]

▪. Ayres JS, Trinidad NJ, Vance RE. Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat Med 2012; 18:799–806. [58]

Bajaj JS, Ridlon JM, Hylemon PB, Thacker LR, et al. Linkage of gut microbiome with cognition in hepatic encephalopathy. Am J Physiol-Gastroint Liver Physiol 2012; 302:G168–G175.

Baquero F, Nombela C. The microbiome as a human organ. Clin Microbiol Infect 2012; 18:2–4. View Full Text | PubMed | CrossRef

Batran SAE, Zakout YMA. Evaluation of improved zirconyl hematoxylin compared to the classical pH 2.5 Alcian blue method for demonstrating acid mucins. Biotech Histochem 2012; 87:226–228. PubMed | CrossRef

Brinkman BM, Hildebrand F, Kubica M, Goosens D, et al. Caspase deficiency alters the murine gut microbiome - art. no. e220. Cell Death Dis 2011; 2.

Bron PA, van Baarlen P, Kleerebezem M. Emerging molecular insights into the interaction between probiotics and the host intestinal mucosa. Nat Rev Immunol 2012; Microbiology. 10:66.

Busch SE, Gurley KE, Moser RD, Kemp CJ. ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model. J Pathol 2012; 227:298–305. View Full Text | PubMed | CrossRef

Cakici O, Akat E. Histopathological Effects of Carbaryl on Digestive System of Snake-eyed Lizard, Ophisops elegans. Bull Environ Contam Toxicol 2012; 88:685–690. PubMed | CrossRef

▪. Castellarin M, Warren RL, Freeman JD, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res 2012; 22:299–306. [67]

Cho I, Blaser MJ. APPLICATIONS OF NEXT-GENERATION SEQUENCING The human microbiome: at the interface of health and disease. Nat Rev Genet 2012; 13:260–270.

▪▪. Claesson MJ, Jeffery IB, Conde S, et al. Gut microbiota composition correlates with diet and health in the elderly. Nature 2012; 488:178–184. [24]

Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol 2012; 28:159–165. View Full Text | PubMed | CrossRef

Daly K, Proudman CJ, Duncan SH, Flint HJ, et al. Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease. Br J Nutr 2012; 107:989–995. PubMed | CrossRef

▪▪. Devkota S, Wang Y, Musch MW, et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in IL10-/- mice. Nature 2012; 487:104–108. [42]

▪. Elinav E, Strowig T, Kau AL, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011; 145:1–13. [31]

Feria-Gervasio D, Denis S, Alric M, Brugere JF. In vitro maintenance of a human proximal colon microbiota using the continuous fermentation system P-ECSIM. Appl Microbiol Biotechnol 2011; 91:1425–1433. PubMed | CrossRef

Flanagan P, Campbell BJ, Rhodes JM. Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans 2011; 39:1067–1072. PubMed | CrossRef

Gosalbes MJ, Abellan JJ, Durban A, Perez-Cobas AE, et al. Metagenomics of human microbiome: beyond 16s rDNA. Clin Microbiol Infect 2012; 18:47–49. View Full Text | PubMed | CrossRef

Greenwood-Van Meerveld B, Prodan CI. Abnormal intestinal function related to hypocupremia in a rodent model. Neurogastroenterol Motil 2012; 24:283-E1112. View Full Text | PubMed | CrossRef

Guarino A, Wudy A, Basile F, Ruberto E, et al. Composition and roles of intestinal microbiota in children. J Matern-Fetal Neonatal Med 2012; 25:63–66. PubMed | CrossRef

Hansen CF, Hernandez A, Mansfield J, Hidalgo A, et al. A high dietary concentration of inulin is necessary to reduce the incidence of swine dysentery in pigs experimentally challenged with Brachyspira hyodysenteriae. Br J Nutr 2011; 106:1506–1513. PubMed | CrossRef

▪. Henao-Mejia J, Elinav E, Jin C, et al. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 2012; 482:179–185. [61]

▪. Hill DA, Siracusa MC, Abt MC, et al. Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat Med 2012; 18:538–546. [19]

▪. Hviid A, Svanström H, Frisch M. Antibiotic use in inflammatory bowel diseases in childhood. Gut 2011; 60:49–54. [21]

Jahng J, Jung IS, Choi EJ, Conklin JL, et al. The effects of methane and hydrogen gases produced by enteric bacteria on ileal motility and colonic transit time. Neurogastroenterol Motil 2012; 24:185-E192. View Full Text | PubMed | CrossRef

▪▪. Johansson ME, Larsson JM, Hansson GC. The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions. Proc Natl Acad Sci USA, 108(Suppl 1)2011; 4659–4665. [12]

Jurgonski A, Juskiewicz J, Kowalska K, Zdunczyk Z. Does dietary inulin affect biological activity of a grapefruit flavonoid-rich extract? - art. no. 31. Nutr Metab 2012; 9:11.

Knauf F, Ko N, Jiang ZR, Robertson WG, et al. Net Intestinal Transport of Oxalate Reflects Passive Absorption and SLC26A6-mediated Secretion. J Am Soc Nephrol 2011; 22:2247–2255. PubMed | CrossRef

Kong H, Kim H, Do H, Lee Y, et al. Structural effects of N-aromatic acyl-amino acid conjugates on their deconjugation in the cecal contents of rats: implication in design of a colon-specific prodrug with controlled conversion rate at the target site. Biopharm Drug Dispos 2011; 32:343–354. PubMed | CrossRef

Kong H, Lee Y, Kim H, Hong S, et al. Susceptibility of glucocorticoids to colonic metabolism and pharmacologic intervention in the metabolism: implication for therapeutic activity of colon-specific glucocorticoid 21-sulfate sodium at the target site. J Pharm Pharmacol 2012; 64:128–138. View Full Text | PubMed

Krajmalnik-Brown R, Ilhan ZE, Kang DW, Di Baise JK. Effects of Gut Microbes on Nutrient Absorption and Energy Regulation. Nutr Clin Pract 2012; 27:201–214. View Full Text | PubMed | CrossRef

Lin SX, Zhang ZR, Xu H, Li L, et al. Site-Specific Incorporation of Photo-Cross-Linker and Bioorthogonal Amino Acids into Enteric Bacterial Pathogens. J Am Chem Soc 2011; 133:20581–20587. PubMed | CrossRef

Lopez-Siles M, Khan TM, Duncan SH, Harmsen HJM, et al. Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth. Appl Environ Microbiol 2012; 78:420–428. PubMed | CrossRef

Marinangeli CPF, Krause D, Harding SV, Rideout TC, et al. Whole and fractionated yellow pea flours modulate insulin, glucose, oxygen consumption, and the caecal microbiome in Golden Syrian hamsters. Appl Physiol Nutr Metab 2011; 36:811–820.

Methe BA, Nelson KE, Pop M, Creasy HH, et al. A framework for human microbiome research. Nature 2012; 486:215–221.

Miyada T, Nakajima A, Ebihara K. Degradation of pectin in the caecum contributes to bioavailability of iron in rats. Br J Nutr 2012; 107:1452–1457. PubMed | CrossRef

Mukdsi MCA, Cano MPG, Gonzalez SN, Medina RB. Administration of Lactobacillus fermentum CRL1446 increases intestinal feruloyl esterase activity in mice. Lett Appl Microbiol 2012; 54:18–25. View Full Text | PubMed | CrossRef

▪. Murphy EF, Cotter PD, Hogan A, et al. Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. Gut 2012; 00:000–000. [41]

Mutlu EA, Gillevet PM, Rangwala H, Sikaroodi M, et al. Colonic microbiome is altered in alcoholism. Am J Physiol-Gastroint Liver Physiol 2012; 302:G966–G978.

Nakao T, Kurita N, Komatsu M, Yoshikawa K, et al. Irinotecan Injures Tight Junction and Causes Bacterial Translocation in Rat. J Surg Res 2012; 173:341–347. PubMed | CrossRef

Nikitenko VI, Stadnikov AA, Kopylov VA. Bacterial translocation from the gastrointestinal tract in healthy and injured rats. J Wound Care 2011; 20:114. PubMed

Nishimura N, Tanabe H, Sasaki Y, Makita Y, et al. Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats. Br J Nutr 2012; 107:485–492. PubMed | CrossRef

Ordaz-Pichardo C, Leon-Sicairos N, Hernandez-Ramirez VI, Talamas-Rohana P, et al. Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis. Biochem Cell Biol 2012; 90:425–434. PubMed | CrossRef

Pabst O, Mowat AM. Oral tolerance to food protein. Mucosal Immunol 2012; 5:232–239.

Plottel CS, Blaser MJ. Microbiome and Malignancy. Cell Host Microbe 2011; 10:324–335.

Proctor LM. The Human Microbiome Project in 2011 and Beyond. Cell Host Microbe 2011; 10:287–291.

Puhl NJ, Uwiera RRE, Yanke LJ, Selinger LB, et al. Antibiotics conspicuously affect community profiles and richness, but not the density of bacterial cells associated with mucosa in the large and small intestines of mice. Anaerobe 2012; 18:67–75. PubMed | CrossRef

Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Curr Opin Microbiol 2012; 15:147–154. PubMed

Rauch M, Lynch SV. The potential for probiotic manipulation of the gastrointestinal microbiome. Curr Opin Biotechnol 2012; 23:192–201. PubMed

Rausch V, Liu L, Apel A, Rettig T, et al. Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment. J Pathol 2012; 227:325–335. View Full Text | PubMed | CrossRef

Remedio RN, Castellar A, Barbosa RA, Gomes RJ, et al. Morphological analysis of colon goblet cells and submucosa in type I diabetic rats submitted to physical training. Microsc Res Tech 2012; 75:821–828. PubMed | CrossRef

Rosenbaum JT, Davey MP. Time for a Gut Check: Evidence for the Hypothesis That HLA-B27 Predisposes to Ankylosing Spondylitis by Altering the Microbiome. Arthritis Rheum 2011; 63:3195–3198. View Full Text | PubMed | CrossRef

▪▪. Round JL, Lee SM, Li J, et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011; 332:974–977. [27]

▪. Russell SL, Gold MJ, Hartmann M, et al. Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Rep 2012; 13:440–447. [20]

Shinoki A, Hara H. Dietary fructo-oligosaccharides improve insulin sensitivity along with the suppression of adipocytokine secretion from mesenteric fat cells in rats. Br J Nutr 2011; 106:1190–1197. PubMed | CrossRef

▪▪. Shulzhenko N, Morgun A, Hsiao W, et al. Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut. Nat Med 2011; 17:1585–1593. [45]

Sommer MOA, Dantas G. Antibiotics and the resistant microbiome. Curr Opin Microbiol 2011; 14:556–563. PubMed | CrossRef

Stone SP, Fuller C, Savage J, Cookson B, et al. Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series study - art. no. e3005. Br Med J 3005; 344:3.

Tehrani AB, Nezami BG, Gewirtz A, Srinivasan S. Obesity and its associated disease: a role for microbiota? Neurogastroenterol Motil 2012; 24:305–311.

Thompson AL. Developmental origins of obesity: Early feeding environments, infant growth, and the intestinal microbiome. Am J Hum Biol 2012; 24:350–360. PubMed | CrossRef

▪. Vaishnava S, Yamamoto M, Severson KM, et al. The antibacterial lectin RegIIIg promotes the spatial segregation of microbiota and host in the intestine. Science 2011; 334:255–258. [10]

Wagner RD, Johnson SJ, Cerniglia CE, Erickson BD. Bovine Intestinal Bacteria Inactivate and Degrade Ceftiofur and Ceftriaxone with Multiple beta-Lactamases. Antimicrob Agents Chemother 2011; 55:4990–4998. PubMed | CrossRef

▪▪. Wang Z, Klipfell E, Bennett BJ, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011; 472:57–63. [47]

Wei XC, Yang Z, Rey FE, Ridaura VK, et al. Fatty Acid Synthase Modulates Intestinal Barrier Function through Palmitoylation of Mucin 2. Cell Host Microbe 2012; 11:140–152. PubMed | CrossRef

▪. Wu GU, Chen J, Hoffmann C, et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334:105–108. [34]

Yang LY, Francois F, Pei ZH. Molecular Pathways: Pathogenesis and Clinical Implications of Microbiome Alteration in Esophagitis and Barrett Esophagus. Clin Cancer Res 2012; 18:2138–2144. PubMed

Young VB. The intestinal microbiota in health and disease. Curr Opin Gastroenterol 2012; 28:63–69. View Full Text | PubMed | CrossRef

Zhu YM, Luo TM, Jobin C, Young HA. Gut microbiota and probiotics in colon tumorigenesis. Cancer Lett 2011; 309:119–127. PubMed | CrossRef

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Computed tomography colonography: emerging evidence to further support clinical effectiveness

Review: (pp. 55–59)

Buchler T, Simonova K, Fencl P, Jarkovsky J, et al. Clinical Outcomes of Patients with Nonseminomatous Germ Cell Tumours and Negative Postchemotherapy Positron Emission Tomography. Cancer Invest 2012; 30:487–492. PubMed | CrossRef

▪▪. Cash BD, Stamps K, McFarland EG, et al. Clinical use of CT colonography for colorectal cancer screening in military training facilities and potential impact on HEDIS® measures. J Am Coll Radiol 2012 (in press). [22]

▪▪. Cash BD, Riddle MS, Bhattacharya I, et al. CT colonography of a medicare-aged population: outcomes observed in an analysis of more than 1400 patients. AJR Am J Roentgenol 2012; 199:W27–W34. [10]

Chen X, Wang XF, Li ZJ, Kong LJ, et al. Molecular cloning, tissue expression and protein structure prediction of the porcine 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) gene. Gene 2012; 495:170–177. PubMed | CrossRef

▪. Johnson CD, Herman BA, Chen M-H, et al. The national CT colonography trial: assessment of accuracy in participants 65 years of age and older. Radiology 2012; 263:401–408. [09]

Kocan F, Avcibasi U, Unak P, Muftuler FZB, et al. Metabolic Comparison of Radiolabeled Bleomycin and Bleomycin-Glucuronide Labeled with Tc-99m. Cancer Biother Radiopharm 2011; 26:573–584. PubMed | CrossRef

Lansdorp-Vogelaar I, Kuntz KM, Knudsen AB, van Ballegooijen M, et al. Contribution of Screening and Survival Differences to Racial Disparities in Colorectal Cancer Rates. Cancer Epidemiol Biomarkers Prev 2012; 21:728–736. PubMed | CrossRef

▪. Macari M, Nevsky G, Bonavita J, et al. CT colonography in senior versus nonsenior patients: extracolonic findings, recommendations for additional imaging, and polyp prevalence. Radiology 2011; 259:767–774. [08]

▪▪. Pickhardt PJ, Hassan C, Halligan S, Marmo R. Colorectal cancer: CT colonography and colonoscopy for detection – systematic review and meta-analysis. Radiology 2011; 259:393–405. [05]

▪▪. Pooler BD, Baumel MJ, Cash BD, et al. Screening CT colonography: multicenter survey of patient experience, preference, and potential impact on adherence. Am J Roentgenol 2012; 198:1361–1366. [20]

Saito Y, Mekuchi M, Kobayashi N, Kimura M, et al. Molecular cloning, molecular evolution and gene expression of cDNAs encoding thyrotropin-releasing hormone receptor subtypes in a teleost, the sockeye salmon (Oncorhynchus nerka). Gen Comp Endocrinol 2011; 174:80–88. PubMed | CrossRef

Shavlokhov VS, Karagyulyan SR, Moiseeva TN, Dzhumabaeva BT, et al. Surgical treatment of relapsing mediastinal and pulmonary tumors in patients with hodgkin's disease and diffuse large b-cell lymphoma. Gematol Transfuziol 2012; 57:18–23. PubMed

▪▪. Stoop EM, de Haan MC, de Wijkerslooth TR, et al. Participation and yield of colonoscopy versus noncathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trial. Lancet Oncol 2012; 13:55–64. [21]

Wilschut JA, Steyerberg EW, van Leerdam ME, Lansdorp-Vogelaar I, et al. How Much Colonoscopy Screening Should Be Recommended to Individuals With Various Degrees of Family History of Colorectal Cancer? Cancer 2011; 117:4166–4174.

▪▪. Zalis ME, Blake MA, Cai W, et al. Diagnostic accuracy of laxative-free computed tomographic colonography for detection of adenomatous polyps in asymptomatic adults a prospective evaluation. Ann Intern Med 2012; 156:692–771. [23]

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Update on idiopathic colitides

Review: (pp. 60–65)

▪▪. Bloomgren G, Richman S, Hotermans C, et al. Risk of natalizumab-associated progressive multifocal leukoencephalopathy. N Engl J Med 2012; 366:1870–1880. [21]

Bouillaud F, Blachier F. Mitochondria and Sulfide: A Very Old Story of Poisoning, Feeding, and Signaling? Antioxid Redox Signal 2011; 15:379–391.

Chang CH, Lin JW, Chen HC, Kuo CW, et al. Non-steroidal anti-inflammatory drugs and risk of lower gastrointestinal adverse events: a nationwide study in Taiwan. Gut 2011; 60:1372–1378.

▪. Colombel JF, Rutgeerts P, Reinisch W, et al. Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology 2011; 141:1194–1201. [07]

Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol 2012; 28:159–165. View Full Text | PubMed | CrossRef

Denning TL, Norris BA, Medina-Contreras O, Manicassamy S, et al. Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization. J Immunol 2011; 187:733–747. PubMed | CrossRef

El-Hawiet A, Kitova EN, Kitov PI, Eugenio L, et al. Binding of Clostridium difficile toxins to human milk oligosaccharides. Glycobiology 2011; 21:1217–1227. PubMed | CrossRef

Flanagan P, Campbell BJ, Rhodes JM. Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans 2011; 39:1067–1072. PubMed | CrossRef

▪▪. Guagnozzi D, Lucendo AJ, Angueira-Lapena T, et al. Prevalence and incidence of microscopic colitis in patients with diarrhoea of unknown aetiology in a region in central Spain. Dig Liver Dis 2012; 44:384–388. [43]

Gustafsson JK, Ermund A, Johansson MEV, Schutte A, et al. An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants. Am J Physiol-Gastroint Liver Physiol 2012; 302:G430–G438.

Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A. Standardized Frozen Preparation for Transplantation of Fecal Microbiota for Recurrent Clostridium difficile Infection. Am J Gastroenterol 2012; 107:761–767. PubMed | CrossRef

Hegan PS, Giral H, Levi M, Mooseker MS. Myosin VI is required for maintenance of brush border structure, composition, and membrane trafficking functions in the intestinal epithelial cell. Cytoskeleton 2012; 69:235–251.

▪. Herreros MD, Garcia-Arranz M, Guadalajara H, et al. Autologous expanded adipose-derived stem cells for the treatment of complex cryptoglandular perianal fistulas: a phase III randomized clinical trial (FATT 1: fistula Advanced Therapy Trial 1) and long-term evaluation. Dis Colon Rectum 2012; 55:762–772. [32]

Hirayama M, Toda R, Ozaki T, Hasegawa J, et al. Concentration Dependence of 5-Aminosalicylic Acid Pharmacological Actions in Intestinal Mucosa after Oral Administration of a pH-Dependent Formulation. Mol Pharm 2011; 8:1083–1089. PubMed

Inoue J, Nishiumi S, Fujishima Y, Masuda A, et al. Autophagy in the intestinal epithelium regulates Citrobacter rodentium infection. Arch Biochem Biophys 2012; 521:95–101. PubMed | CrossRef

Johansson MEV, Ambort D, Pelaseyed T, Schutte A, et al. Composition and functional role of the mucus layers in the intestine. Cell Mol Life Sci 2011; 68:3635–3641. PubMed | CrossRef

Kelly CP. Large intestine. Curr Opin Gastroenterol 2012; 28:36–38. View Full Text | PubMed | CrossRef

Khanna S, Pardi DS. IBD Poor outcomes after Clostridium difficile infection in IBD. Nat Rev Gastroenterol Hepatol 2012; 9:307–308. View Full Text | PubMed | CrossRef

▪. Kiesslich R, Duckworth CA, Moussata D, et al. Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut 2011. [56]

Knauf F, Ko N, Jiang ZR, Robertson WG, et al. Net Intestinal Transport of Oxalate Reflects Passive Absorption and SLC26A6-mediated Secretion. J Am Soc Nephrol 2011; 22:2247–2255. PubMed | CrossRef

Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol 2011; 62:591–599. PubMed

Lee Y, Kim J, Kim H, Kang S, et al. N-Succinylaspart-1-yl Celecoxib is a Potential Colon-Specific Prodrug of Celecoxib with Improved Therapeutic Properties. J Pharm Sci 2012; 101:1831–1842. PubMed | CrossRef

▪▪. Lichtenstein GR, Rutgeerts P, Sandborn WJ, et al. A pooled analysis of infections, malignancy, and mortality in infliximab- and immunomodulator-treated adult patients with inflammatory bowel disease. Am J Gastroenterol 2012; 107:1051–1063. [35]

Mimoun S, Andriamihaja M, Chaumontet C, Atanasiu C, et al. Detoxification of H2S by Differentiated Colonic Epithelial Cells: Implication of the Sulfide Oxidizing Unit and of the Cell Respiratory Capacity. Antioxid Redox Signal 2012; 17:1–10. PubMed | CrossRef

Nakao T, Kurita N, Komatsu M, Yoshikawa K, et al. Irinotecan Injures Tight Junction and Causes Bacterial Translocation in Rat. J Surg Res 2012; 173:341–347. PubMed | CrossRef

Ning ZY, An YF, Qi WB, Wang H, et al. Na+/H+ Exchanger 1 Gene Expression in Tissues of Yellow Chicken. Biochem Genet 2012; 50:227–234. PubMed | CrossRef

Ordaz-Pichardo C, Leon-Sicairos N, Hernandez-Ramirez VI, Talamas-Rohana P, et al. Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis. Biochem Cell Biol 2012; 90:425–434. PubMed | CrossRef

▪▪. Reinisch W, Sandborn WJ, Rutgeerts P, et al. Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies. Inflamm Bowel Dis 2012; 18:201–211. [08]

Said HM. Intestinal absorption of water-soluble vitamins in health and disease. Biochem J 2011; 437:357–372. PubMed | CrossRef

▪. Sandborn WJ, van Assche G, Reinisch W, et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012; 142:257–265. e1–e3 [09]

Segata N, Izard J, Waldron L, Gevers D, et al. Metagenomic biomarker discovery and explanation - art. no. R60. Genome Biol 2011; 12:R60. PubMed | CrossRef

Wei XC, Yang Z, Rey FE, Ridaura VK, et al. Fatty Acid Synthase Modulates Intestinal Barrier Function through Palmitoylation of Mucin 2. Cell Host Microbe 2012; 11:140–152. PubMed | CrossRef

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Motility disorders of the colon and rectum

Review: (pp. 66–71)

Bayguinov PO, Broadhead MJ, Okamoto T, Hennig GW, et al. Activity in varicosities within the myenteric plexus between and during the colonic migrating motor complex in the isolated murine large intestine. Neurogastroenterol Motil 2012; 24:e185–e201. View Full Text | PubMed | CrossRef

Broadhead MJ, Bayguinov PO, Okamoto T, Heredia DJ, et al. Ca2+ transients in myenteric glial cells during the colonic migrating motor complex in the isolated murine large intestine. J Physiol-London 2012; 590:335–350.

▪. Brown PM, Drossman DA, Wood AJ, et al. The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome. Gastroenterology 2011; 141:507–516. [18]

Denning TL, Norris BA, Medina-Contreras O, Manicassamy S, et al. Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization. J Immunol 2011; 187:733–747. PubMed | CrossRef

Jahng J, Jung IS, Choi EJ, Conklin JL, et al. The effects of methane and hydrogen gases produced by enteric bacteria on ileal motility and colonic transit time. Neurogastroenterol Motil 2012; 24:85-E192.

Kaska M, Hoffmann P, Oberreiter M. Mechanical ileus caused by a tablet of Tralgit SR 100 stuck in a stenotic rectum affected by carcinoma : case report and literature survey. Acta Gastro-Enterol Belg 2011; 74:564–566.

Kerckhoffs APM, ter Linde JJM, Akkermans LMA, Samsom M. SERT and TPH-1 mRNA expression are reduced in irritable bowel syndrome patients regardless of visceral sensitivity state in large intestine. Am J Physiol-Gastroint Liver Physiol 2012; 302:G1053–G1060.

Konturek PC, Brzozowski T, Konturek SJ. Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol 2011; 62:591–599. PubMed

Lei J, Howard MJ. Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis. Development 2011; 138:4789–4800. PubMed | CrossRef

▪. Lembo AJ, Schneier HA, Shiff SJ, et al. Two randomized trials of linaclotide for chronic constipation. N Engl J Med 2011; 365:527–536. [22]

▪. Michna E, Blonsky ER, Schulman S, et al. Subcutaneous methylnaltrexone for treatment of opioid-induced constipation in patients with chronic, nonmalignant pain: a randomized controlled study. J Pain 2011; 12:554–562. [20]

▪. Peery AF, Barrett PR, Park D, et al. A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 2012; 142:266–72e1. [11]

▪▪. Rao SS, Camilleri M, Hasler WL, et al. Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European neurogastroenterology and motility societies. Neurogastroenterol Motil 2011; 23:8–23. [04]

Silva LS, Sartori AL, Zaniolo LM, da Silva AV, et al. Toxoplasma gondii: Myenteric neurons of intraperitoneally inoculated rats show quantitative and morphometric alterations. Exp Parasitol 2011; 129:5–10. PubMed | CrossRef

▪. Wong BS, Camilleri M, McKinzie S, et al. Effects of A3309, an ileal bile acid transporter inhibitor, on colonic transit and symptoms in females with functional constipation. Am J Gastroenterol 2011; 106:2154–2164. [16]

Wookey PJ, Turner K, Furness JB. Transient expression of the calcitonin receptor by enteric neurons of the embryonic and early post-natal mouse. Cell Tissue Res 2012; 347:311–317. PubMed | CrossRef

Yik YI, Cain TM, Tudball CF, Cook DJ, et al. Nuclear transit studies of patients with intractable chronic constipation reveal a subgroup with rapid proximal colonic transit. J Pediatr Surg 2011; 46:1406–1411. PubMed | CrossRef

Zaniolo LM, da Silva AV, Sant'Ana DMG, Araujo EJD. Toxoplasma gondii infection causes morphological changes in caecal myenteric neurons. Exp Parasitol 2012; 130:103–109. PubMed | CrossRef

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New developments in colorectal surgery

Review: (pp. 72–78)

▪▪. Abraham-Nordling M, Hjern F, Pollack J, et al. Randomized clinical trial of fluid restriction in colorectal surgery. Br J Surg 2012; 99:186–191. [43]

▪. Acar HI, Kuzu MA. Perineal and pelvic anatomy of extralevator abdominoperineal excision for rectal cancer: cadaveric dissection. Dis Colon Rectum 2011; 54:1179–1183. [06]

▪. Al-Refaie WB, Parsons HM, Habermann EB, et al. Operative outcomes beyond 30-day mortality: colorectal cancer surgery in oldest old. Ann Surg 2011; 253:947–952. [32]

▪▪. Baik SH, Gincherman M, Mutch MG, et al. Laparoscopic vs open resection for patients with rectal cancer: comparison of perioperative outcomes and long-term survival. Dis Colon Rectum 2011; 54:6–14. [22]

▪. Billeter AT, Polk Jr HC, Hohmann SF, et al. Mortality after elective colon resection: the search for outcomes that define quality in surgical practice. J Am Coll Surg 2012; 214:436–443. [34]

▪▪. Chabok A, Pahlman L, Hjern F, et al. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg 2012; 99:532–539. [42]

▪▪. Champagne BJ, Papaconstantinou HT, Parmar SS, et al. Single-incision versus standard multiport laparoscopic colectomy: a multicenter, case-controlled comparison. Ann Surg 2012; 255:66–69. [50]

▪▪. Chang GJ, You YN, Park IJ, et al. Pretreatment high-resolution rectal MRI and treatment response to neoadjuvant chemoradiation. Dis Colon Rectum 2012; 55:371–377. [17]

▪. Chen Z, Duldulao MP, Li W, et al. Molecular diagnosis of response to neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer. J Am Coll Surg 2011; 212:1008–1017. [21]

▪. Davis DM, Marcet JE, Frattini JC, et al. Is it time to lower the recommended screening age for colorectal cancer? J Am Coll Surg 2011; 213:352–361. [24]

▪. de Campos-Lobato LF, Geisler DP, da Luz Moreira A, et al. Neoadjuvant therapy for rectal cancer: the impact of longer interval between chemoradiation and surgery. J Gastrointest Surg 2011; 15:444–450. [02]

▪. de Campos-Lobato LF, Stocchi L, Dietz DW, et al. Prone or lithotomy positioning during an abdominoperineal resection for rectal cancer results in comparable oncologic outcomes. Dis Colon Rectum 2011; 54:939–946. [04]

▪. de Korte N, Kuyvenhoven JP, van der Peet DL, et al. Mild colonic diverticulitis can be treated without antibiotics. A case-control study. Colorectal Dis 2012; 14:325–330. [41]

▪▪. de Korte N, Unlu C, Boermeester MA, et al. Use of antibiotics in uncomplicated diverticulitis. Br J Surg 2011; 98:761–767. [40]

▪▪. De laney CP, Brady K, Woconish D, et al. Towards optimizing perioperative colorectal care: outcomes for 1,000 consecutive laparoscopic colon procedures using enhanced recovery pathways. Am J Surg 2012; 203:353–355. [44]

▪. Garcia-Aguilar J, Chen Z, Smith DD, et al. Identification of a biomarker profile associated with resistance to neoadjuvant chemoradiation therapy in rectal cancer. Ann Surg 2011; 254:486–492. [29]

▪. Gervaz P, Bandiera-Clerc C, Buchs NC, et al. Scoring system to predict the risk of surgical-site infection after colorectal resection. Br J Surg 2012; 99:589–595. [36]

▪. Gorissen KJ, Benning D, Berghmans T, et al. Risk of anastomotic leakage with nonsteroidal anti-inflammatory drugs in colorectal surgery. Br J Surg 2012; 99:721–727. [37]

▪▪. Greenblatt DY, Rajamanickam V, Pugely AJ, et al. Short-term outcomes after laparoscopic-assisted proctectomy for rectal cancer: results from the ACS NSQIP. J Am Coll Surg 2011; 212:844–854. [23]

▪. Guillamondegui OD, Gunter OL, Hines L, et al. Using the National Surgical Quality Improvement Program and the Tennessee Surgical Quality Collaborative to improve surgical outcomes. J Am Coll Surg 2012; 214:709–714. [30]

Hoffman JM, Tyler K, MacEachern SJ, Balemba OB, et al. Activation of Colonic Mucosal 5-HT4 Receptors Accelerates Propulsive Motility and Inhibits Visceral Hypersensitivity. Gastroenterology 2012; 142:844. PubMed | CrossRef

▪. Hull TL, Joyce MR, Geisler DP, Coffey JC. Adhesions after laparoscopic and open ileal pouch-anal anastomosis surgery for ulcerative colitis. Br J Surg 2012; 99:270–275. [39]

Ishii H, Taniguchi H, Shiozaki A, Kuriu Y, et al. Use of Multidetector-Row Computed Tomography to Evaluate Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: Influence on Surgical Decision-Making. Hepato-Gastroenterol 2012; 59:884–888.

Islam K, Fukiya S, Hagio M, Fujii N, et al. Bile Acid Is a Host Factor That Regulates the Composition of the Cecal Microbiota in Rats. Gastroenterology 2011; 141:1773–1781. PubMed | CrossRef

▪. Jackson RS, Amdur RL, White JC, Macsata RA. Hyperglycemia is associated with increased risk of morbidity and mortality after colectomy for cancer. J Am Coll Surg 2012; 214:68–80. [33]

▪. Kim SJ, Ryu GO, Choi BJ, et al. The short-term outcomes of conventional and single-port laparoscopic surgery for colorectal cancer. Ann Surg 2011; 254:933–940. [51]

▪▪. Lambregts DM, Maas M, Bakers FC, et al. Long-term follow-up features on rectal MRI during a wait-and-see approach after a clinical complete response in patients with rectal cancer treated with chemoradiotherapy. Dis Colon Rectum 2011; 54:1521–1528. [18]

▪. Leong KJ, Wei W, Tannahill LA, et al. Methylation profiling of rectal cancer identifies novel markers of early-stage disease. Br J Surg 2011; 98:724–734. [28]

Levin DE, Grikscheit TC. Tissue-engineering of the gastrointestinal tract. Curr Opin Pediatr 2012; 24:365–370. View Full Text | PubMed | CrossRef

▪. Levine EA, Blazer 3rd DG, Kim MK, et al. Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes. J Am Coll Surg 2012; 214:599–606. [25]

▪. Lovely JK, Maxson PM, Jacob AK, et al. Case-matched series of enhanced versus standard recovery pathway in minimally invasive colorectal surgery. Br J Surg 2012; 99:120–126. [45]

▪▪. Makino T, Milsom JW, Lee SW. Feasibility and safety of single-incision laparoscopic colectomy: a systematic review. Ann Surg 2012; 255:667–676. [52]

Okuno K, Horiuchi T, Ishibashi T, Shigeoka H, et al. Prognostic Factors in Gastrointestinal Perforation. Hepato-Gastroenterol 2011; 58:1598–1602.

▪. Park KT, Tsai R, Perez F, et al. Cost-effectiveness of early colectomy with ileal pouch-anal anastamosis versus standard medical therapy in severe ulcerative colitis. Ann Surg 2012; 256:117–124. [38]

▪. Pastor C, Subtil JC, Sola J, et al. Accuracy of endoscopic ultrasound to assess tumor response after neoadjuvant treatment in rectal cancer: can we trust the findings? Dis Colon Rectum 2011; 54:1141–1146. [19]

Peterson CY, Osen HB, Cao HST, Yu PT, et al. The Battle of the Sexes: Women Win Out in Gastrointestinal Surgery. J Surg Res 2011; 170:E23–E28. PubMed | CrossRef

▪. Ratto C, Parello A, Donisi L, et al. Novel bulking agent for faecal incontinence. Br J Surg 2011; 98:1644–1652. [46]

▪. Rijcken E, Mennigen R, Argyris I, et al. Single-incision laparoscopic surgery for ileocolic resection in Crohn's disease. Dis Colon Rectum 2012; 55:140–146. [49]

▪. Ruby JA, Leibold T, Akhurst TJ, et al. FDG-PET assessment of rectal cancer response to neoadjuvant chemoradiotherapy is not associated with long-term prognosis: a prospective evaluation. Dis Colon Rectum 2012; 55:378–386. [20]

▪▪. Ruiz-Tovar J, Santos J, Arroyo A, et al. Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery. J Am Coll Surg 2012; 214:202–207. [31]

▪. Sehgal R, Berg A, Polinski JI, et al. Mutations in IRGM are associated with more frequent need for surgery in patients with ileocolonic Crohn's disease. Dis Colon Rectum 2012; 55:115–121. [26]

▪. Sehgal R, Berg A, Polinski JI, et al. Genetic risk profiling and gene signature modeling to predict risk of complications after IPAA. Dis Colon Rectum 2012; 55:239–248. [27]

▪. Simunovic M, Jacob S, Coates AJ, et al. Outcomes following a limited approach to radiotherapy in rectal cancer. Br J Surg 2011; 98:1483–1488. [01]

▪. Steinhagen E, Shia J, Markowitz AJ, et al. Systematic immunohistochemistry screening for Lynch syndrome in early age-of-onset colorectal cancer patients undergoing surgical resection. J Am Coll Surg 2012; 214:61–67. [35]

▪. Tayyab M, Sharma A, Ragg JL, et al. Evaluation of the impact of implementing the prone jackknife position for the perineal phase of abdominoperineal excision of the rectum. Dis Colon Rectum 2012; 55:316–321. [05]

▪. Waters JA, Rapp BM, Guzman MJ, et al. Single-port laparoscopic right hemicolectomy: the first 100 resections. Dis Colon Rectum 2012; 55:134–139. [48]

Wierzbicki T, Szmeja J, Borejsza-Wysocki M, Meczynski M, et al. Massive bleeeding from upper gastrointestinal tract as a symptom of rupture of splenic artery aneurysm to stomach. Med Sci Monitor 2012; 18:CS8–CS11.

▪. Wong MT, Meurette G, Wyart V, et al. The artificial bowel sphincter: a single institution experience over a decade. Ann Surg 2011; 254:951–956. [47]

Back to Top | Article Outline
Fecal microbiota transplantation: past, present and future

Review: (pp. 79–84)

Alcaraz I, Cerroni L, Rutten A, Kutzner H, et al. Cutaneous Metastases From Internal Malignancies: A Clinicopathologic and Immunohistochemical Review. Am J Dermatopathol 2012; 34:347–390. View Full Text | PubMed | CrossRef

Bakken JS, Borody T, Brandt LJ, Brill JV, et al. Treating Clostridium difficile Infection With Fecal Microbiota Transplantation. Clin Gastroenterol Hepatol 2011; 9:1044–1049. PubMed | CrossRef

▪▪. Bakken JS, Borody T, Brandt LJ, et al. Treating Clostridium difficile infection with fecal microbiota transplantation. Clin Gastroenterol and Hepatol 2011; 9:1044–1049. [14]

Baquero F, Nombela C. The microbiome as a human organ. Clin Microbiol Infect 2012; 18:2–4. View Full Text | PubMed | CrossRef

▪. Brandt LJ, Aroniadis OC, Mellow M, et al. Long-term follow-up of colonoscopic fecal microbiota transplant for recurrent Clostridium difficile infection. Am J Gastroenterol 2012; 107:1079–1087. [21]

Feria-Gervasio D, Denis S, Alric M, Brugere JF. In vitro maintenance of a human proximal colon microbiota using the continuous fermentation system P-ECSIM. Appl Microbiol Biotechnol 2011; 91:1425–1433. PubMed | CrossRef

▪▪. Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis 2011; 53:994–1002. [20]

Proctor LM. The Human Microbiome Project in 2011 and Beyond. Cell Host Microbe 2011; 10:287–291.

▪▪. Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines in Clostridium difficile infections. ACG Guidelines. 2012 (in press). [26]

Back to Top | Article Outline
Microbiota and innate immunity in intestinal inflammation and neoplasia

Review: (pp. 85–91)

Ahn J, Chen CY, Hayes RB. Oral microbiome and oral and gastrointestinal cancer risk. Cancer Causes Control 2012; 23:399–404. PubMed | CrossRef

▪▪. Arumugam M, Raes J, Pelletier E, et al. Enterotypes of the human gut microbiome. Nature 2011; 473:174–180. [18]

Baquero F, Nombela C. The microbiome as a human organ. Clin Microbiol Infect 2012; 18:2–4. View Full Text | PubMed | CrossRef

Boparai KS, Dekker E, Polak MM, Musler AR, et al. A Serrated Colorectal Cancer Pathway Predominates over the Classic WNT Pathway in Patients with Hyperplastic Polyposis Syndrome. Am J Pathol 2011; 178:2700–2707. PubMed | CrossRef

Bouillaud F, Blachier F. Mitochondria and Sulfide: A Very Old Story of Poisoning, Feeding, and Signaling? Antioxid Redox Signal 2011; 15:379–391.

Brady-West D, Blake G. Clinicopathological Features and Outcome of Gastrointestinal Stromal Tumors in an Afro-Caribbean Population. J Natl Med Assoc 2012; 104:72–77. PubMed

Brinkman BM, Hildebrand F, Kubica M, Goosens D, et al. Caspase deficiency alters the murine gut microbiome - art. no. e220. Cell Death Dis 2011; 2.

Cagayan M. High-Risk Metastatic Gestational Trophoblastic Neoplasia Primary Management with EMA-CO (Etoposide, Methotrexate, Actinomycin D, Cyclophosphamide and Vincristine) Chemotherapy. J Reprod Med 2012; 57:231–236. PubMed

Can B, Gun S, Aydin O, Kandemir B. Primary Intestinal-Type Adenoma of the Vagina Arising Directly from Endocervical-Type Adenosis A Case Report. J Reprod Med 2012; 57:68–73. PubMed

▪. Castellarin M, Warren RL, Freeman JD, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma. Genome Res 2012; 22:299–306. [13]

Celestino R, Lima J, Faustino A, Maximo V, et al. A novel germline SDHB mutation in a gastrointestinal stromal tumor patient without bona fide features of the Carney-Stratakis dyad. Fam Cancer 2012; 11:189–194. PubMed | CrossRef

▪. Chen GY, Liu M, Wang F, et al. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 2011; 186:7187–7194. [45]

Daly K, Proudman CJ, Duncan SH, Flint HJ, et al. Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease. Br J Nutr 2012; 107:989–995. PubMed | CrossRef

Dijkgraaf I, Franssen GM, McBride WJ, D'Souza CA, et al. PET of Tumors Expressing Gastrin-Releasing Peptide Receptor with an F-18-Labeled Bombesin Analog. J Nucl Med 2012; 53:947–952. PubMed | CrossRef

Dragan R, Dejan S, Nebojsa M, Vinka V, et al. Synchronous Appearance of Gastric Gastrointestinal Stromal Tumors and Colorectal Adenocarcinoma: A Case Report. Hepato-Gastroenterol 2011; 58:2171–2174.

▪. Elinav E, Strowig T, Kau AL, et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011; 145:745–757. [43]

▪. Eyking A, Ey B, Runzi M, et al. Toll-like receptor 4 variant D299G induces features of neoplastic progression in Caco-2 intestinal cells and is associated with advanced human colon cancer. Gastroenterology 2011; 141: 2154–2165. [55]

Ferguson LR. Potential value of nutrigenomics in Crohn's disease. Nat Rev Gastroenterol Hepatol 2012; 9:260–270. View Full Text | PubMed | CrossRef

Flanagan P, Campbell BJ, Rhodes JM. Bacteria in the pathogenesis of inflammatory bowel disease. Biochem Soc Trans 2011; 39:1067–1072. PubMed | CrossRef

▪. Fu J, Wei B, Wen T, et al. Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J Clin Invest 2011; 121:1657–1666. [31]

▪. Goodwin AC, Destefano Shields CE, Wu S, et al. Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis. Proc Natl Acad Sci U S A 2011; 108:15354–15359. [17]

Gosalbes MJ, Abellan JJ, Durban A, Perez-Cobas AE, et al. Metagenomics of human microbiome: beyond 16s rDNA. Clin Microbiol Infect 2012; 18:47–49. View Full Text | PubMed | CrossRef

Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A. Standardized Frozen Preparation for Transplantation of Fecal Microbiota for Recurrent Clostridium difficile Infection. Am J Gastroenterol 2012; 107:761–767. PubMed | CrossRef

▪▪. Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646–674. [03]

Hansen CF, Hernandez A, Mansfield J, Hidalgo A, et al. A high dietary concentration of inulin is necessary to reduce the incidence of swine dysentery in pigs experimentally challenged with Brachyspira hyodysenteriae. Br J Nutr 2011; 106:1506–1513. PubMed | CrossRef

Hyslop T, Weinberg DS, Schulz S, Barkun A, et al. Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer. J Surg Oncol 2012; 106:24–30. View Full Text | PubMed | CrossRef

Ishii H, Taniguchi H, Shiozaki A, Kuriu Y, et al. Use of Multidetector-Row Computed Tomography to Evaluate Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: Influence on Surgical Decision-Making. Hepato-Gastroenterol 2012; 59:884–888.

Jones NB, Shah MH, Bloomston M. Liver-Directed Therapies in Patients With Advanced Neuroendocrine Tumors. J Natl Compr Cancer Netw 2012; 10:765–774. PubMed

Kaltenbach JC, Fry AE, Colpitts KM, Faszewski EE. Apoptosis in the digestive tract of herbivorous Rana pipiens larvae and carnivorous Ceratophrys ornata larvae: An immunohistochemical study. J Morphol 2012; 273:103–108. PubMed | CrossRef

▪. Kane M, Case LK, Kopaskie K, et al. Successful transmission of a retrovirus depends on the commensal microbiota. Science 2011; 334:245–249. [23]

Kim H, Kim JH, Lim JS, Choi JY, et al. MRI Findings of Rectal Submucosal Tumors. Korean J Radiol 2011; 12:487–498. PubMed | CrossRef

Kim SJ, Choi CW, Mun YC, Oh SY, et al. Multicenter retrospective analysis of 581 patients with primary intestinal non-hodgkin lymphoma from the Consortium for Improving Survival of Lymphoma (CISL) - art. no. 321. BMC Cancer 2011; 11:29.

Knoop KA, Butler BR, Kumar N, Newberry RD, et al. Distinct Developmental Requirements for Isolated Lymphoid Follicle Formation in the Small and Large Intestine RANKL Is Essential Only in the Small Intestine. Am J Pathol 2011; 179:1861–1871. PubMed | CrossRef

Kong H, Kim H, Do H, Lee Y, et al. Structural effects of N-aromatic acyl-amino acid conjugates on their deconjugation in the cecal contents of rats: implication in design of a colon-specific prodrug with controlled conversion rate at the target site. Biopharm Drug Dispos 2011; 32:343–354. PubMed | CrossRef

Koo J, Mertens RB, Mirocha JM, Wang HL, et al. Value of Islet 1 and PAX8 in identifying metastatic neuroendocrine tumors of pancreatic origin. Mod Pathol 2012; 25:893–901. PubMed | CrossRef

▪. Kostic AD, Gevers D, Pedamallu CS, et al. Genomic analysis identifies association of Fusobacterium with colorectal carcinoma. Genome Res 2012; 22:292–298. [12]

Kulke MH, Benson AB, Bergsland E, Berlin JD, et al. Neuroendocrine Tumors Clinical Practice Guidelines in Oncology. J Natl Compr Cancer Netw 2012; 10:724–764. PubMed

Kuntz KM, Lansdorp-Vogelaar I, Rutter CM, Knudsen AB, et al. A Systematic Comparison of Microsimulation Models of Colorectal Cancer: The Role of Assumptions about Adenoma Progression. Med Decis Mak 2011; 31:530–539. PubMed | CrossRef

▪. Kuss SK, Best GT, Etheredge CA, et al. Intestinal microbiota promote enteric virus replication and systemic pathogenesis. Science 2011; 334:249–252. [24]

Ladoire S, Martin F, Ghiringhelli F. Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: the paradox of colorectal cancer. Cancer Immunol Immunother 2011; 60:909–918. PubMed | CrossRef

Lansdorp-Vogelaar I, Kuntz KM, Knudsen AB, van Ballegooijen M, et al. Contribution of Screening and Survival Differences to Racial Disparities in Colorectal Cancer Rates. Cancer Epidemiol Biomarkers Prev 2012; 21:728–736. PubMed | CrossRef

Lee EW, Wong D, Tafti BA, Prieto V, et al. Irreversible Electroporation in Eradication of Rabbit VX2 Liver Tumor. J Vasc Interv Radiol 2012; 23:833–840. View Full Text | PubMed | CrossRef

Lin JM, Goldblum JR, Bennett AE, Bronner MP, et al. Composite Intestinal Adenoma-Microcarcinoid. Am J Surg Pathol 2012; 36:292–295. View Full Text | PubMed | CrossRef

Lopez-Siles M, Khan TM, Duncan SH, Harmsen HJM, et al. Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth. Appl Environ Microbiol 2012; 78:420–428. PubMed | CrossRef

Lurain JR, Schink JC. Importance of Salvage Therapy in the Management of High-Risk Gestational Trophoblastic Neoplasia. J Reprod Med 2012; 57:219–224. PubMed

Mansueto P, Iacono G, Seidita A, D'Alcamo A, et al. Review article: intestinal lymphoid nodular hyperplasia in children - the relationship to food hypersensitivity. Aliment Pharmacol Ther 2012; 35:1000–1009. View Full Text | PubMed

Marinangeli CPF, Krause D, Harding SV, Rideout TC, et al. Whole and fractionated yellow pea flours modulate insulin, glucose, oxygen consumption, and the caecal microbiome in Golden Syrian hamsters. Appl Physiol Nutr Metab 2011; 36:811–820.

Medina-Arana V, Delgado L, Bravo A, Martin J, et al. Tumor spectrum in lynch syndrome, DNA mismatch repair system and endogenous carcinogens. J Surg Oncol 2012; 106:10–16. View Full Text | PubMed | CrossRef

Mehta AI, Mohrhaus CA, Husain AM, Karikari IO, et al. Dorsal Column Mapping for Intramedullary Spinal Cord Tumor Resection Decreases Dorsal Column Dysfunction. J Spinal Disord Tech 2012; 25:205–209. View Full Text | PubMed | CrossRef

Methe BA, Nelson KE, Pop M, Creasy HH, et al. A framework for human microbiome research. Nature 2012; 486:215–221.

Mimoun S, Andriamihaja M, Chaumontet C, Atanasiu C, et al. Detoxification of H2S by Differentiated Colonic Epithelial Cells: Implication of the Sulfide Oxidizing Unit and of the Cell Respiratory Capacity. Antioxid Redox Signal 2012; 17:1–10. PubMed | CrossRef

▪. Minot S, Sinha R, Chen J, et al. The human gut virome: inter-individual variation and dynamic response to diet. Genome Res 2011; 21:1616–1625. [25]

Miyada T, Nakajima A, Ebihara K. Degradation of pectin in the caecum contributes to bioavailability of iron in rats. Br J Nutr 2012; 107:1452–1457. PubMed | CrossRef

Nishimura N, Tanabe H, Sasaki Y, Makita Y, et al. Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats. Br J Nutr 2012; 107:485–492. PubMed | CrossRef

▪▪. No Authors Given. Human Microbiome Project Consortium. A framework for human microbiome research. Nature 2012; 486:215–221. [20]

▪▪. No Authors Given. Project THM. The Human Microbiome Project Collection. 2012. http://www.ploscollections.org/hmp [21]

▪. Normand S, De lanoye-Crespin A, Bressenot A, et al. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci U S A 2011; 108:9601–9606. [44]

Oh JR, Min JJ, Song HC, Chong A, et al. A Stepwise Approach Using Metabolic Volume and SUVmax to Differentiate Malignancy and Dysplasia From Benign Colonic Uptakes on F-18-FDG PET/CT. Clin Nucl Med 2012; 37:E134–E140. View Full Text | PubMed | CrossRef

Ordaz-Pichardo C, Leon-Sicairos N, Hernandez-Ramirez VI, Talamas-Rohana P, et al. Effect of bovine lactoferrin in a therapeutic hamster model of hepatic amoebiasis. Biochem Cell Biol 2012; 90:425–434. PubMed | CrossRef

Paulson AS, Bergsland EK. Systemic Therapy for Advanced Carcinoid Tumors: Where Do We Go From Here? J Natl Compr Cancer Netw 2012; 10:785–793.

Peycru T, Jarry J, Soubeyran I. Sporadic Medullary Carcinoma of the Ileum. Clin Gastroenterol Hepatol 2011; 9:XXIV. PubMed

Plottel CS, Blaser MJ. Microbiome and Malignancy. Cell Host Microbe 2011; 10:324–335.

▪▪. Project THM. Structure, function and diversity of the healthy human microbiome. Nature 2012; 486:207–214. [19]

Puhl NJ, Uwiera RRE, Yanke LJ, Selinger LB, et al. Antibiotics conspicuously affect community profiles and richness, but not the density of bacterial cells associated with mucosa in the large and small intestines of mice. Anaerobe 2012; 18:67–75. PubMed | CrossRef

Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Curr Opin Microbiol 2012; 15:147–154. PubMed

Rauch M, Lynch SV. The potential for probiotic manipulation of the gastrointestinal microbiome. Curr Opin Biotechnol 2012; 23:192–201. PubMed

Rauh-Hain JA, Growdon WB, Braga A, Goldstein DP, et al. Gestational Trophoblastic Neoplasia in Adolescents. J Reprod Med 2012; 57:237–242. PubMed

Reidy-Lagunes DL. Systemic Therapy for Advanced Pancreatic Neuroendocrine Tumors: An Update. J Natl Compr Cancer Netw 2012; 10:777–783. PubMed

Rosenbaum JT, Davey MP. Time for a Gut Check: Evidence for the Hypothesis That HLA-B27 Predisposes to Ankylosing Spondylitis by Altering the Microbiome. Arthritis Rheum 2011; 63:3195–3198. View Full Text | PubMed | CrossRef

Rosty C, Buchanan DD, Walsh MD, Pearson SA, et al. Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients From Genetics Clinics. Am J Surg Pathol 2012; 36:876–882. View Full Text | PubMed | CrossRef

▪. Schiechl G, Bauer B, Fuss I, et al. Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages. J Clin Invest 2011; 121:1692–1708. [48]

Shah NT, Barroilhet L, Berkowitz RS, Goldstein DP, et al. A Cost Analysis of First-Line Chemotherapy for Low-Risk Gestational Trophoblastic Neoplasia. J Reprod Med 2012; 57:211–218. PubMed

Sherwood RI, Maehr R, Mazzoni EO, Melton DA. Wnt signaling specifies and patterns intestinal endoderm. Mech Dev 2011; 128:387–400.

Shinoki A, Hara H. Dietary fructo-oligosaccharides improve insulin sensitivity along with the suppression of adipocytokine secretion from mesenteric fat cells in rats. Br J Nutr 2011; 106:1190–1197. PubMed | CrossRef

Stone SP, Fuller C, Savage J, Cookson B, et al. Evaluation of the national Cleanyourhands campaign to reduce Staphylococcus aureus bacteraemia and Clostridium difficile infection in hospitals in England and Wales by improved hand hygiene: four year, prospective, ecological, interrupted time series study - art. no. e3005. Br Med J 3005; 344:3.

Sweetser S, Smyrk TC, Sugumar A. Serrated polyps: critical precursors to colorectal cancer. Expert Rev Gastroenterol Hepatol 2011; 5:627–635. View Full Text | PubMed | CrossRef

Szeliga J, Klodzinska E, Jackowski M, Buszewski B. The clinical use of a fast screening test based on technology of capillary zone electrophoresis (CZE) for identification of Escherichia coli infection in biological material. Med Sci Monitor 2011; 17:MT91–MT96.

Thompson AL. Developmental origins of obesity: Early feeding environments, infant growth, and the intestinal microbiome. Am J Hum Biol 2012; 24:350–360. PubMed | CrossRef

Tian Y, Huang TX, Li GC, Liu J, et al. Apoptosis of CT26 colorectal cancer cells induced by Clostridium difficile toxin A stimulates potent anti-tumor immunity. Biochem Biophys Res Commun 2012; 422:15–21. PubMed | CrossRef

▪. Vaishnava S, Yamamoto M, Severson KM, et al. The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science 2011; 334:255–258. [28]

Wagner RD, Johnson SJ, Cerniglia CE, Erickson BD. Bovine Intestinal Bacteria Inactivate and Degrade Ceftiofur and Ceftriaxone with Multiple beta-Lactamases. Antimicrob Agents Chemother 2011; 55:4990–4998. PubMed | CrossRef

Whyte S, Walsh C, Chilcott J. Bayesian Calibration of a Natural History Model with Application to a Population Model for Colorectal Cancer. Med Decis Mak 2011; 31:625–641. PubMed | CrossRef

Yang LY, Francois F, Pei ZH. Molecular Pathways: Pathogenesis and Clinical Implications of Microbiome Alteration in Esophagitis and Barrett Esophagus. Clin Cancer Res 2012; 18:2138–2144. PubMed

Zhu YM, Luo TM, Jobin C, Young HA. Gut microbiota and probiotics in colon tumorigenesis. Cancer Lett 2011; 309:119–127. PubMed | CrossRef

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Advances in diagnostic and therapeutic colonoscopy

Guldfred LA, Daugaard S, von Buchwald C. Brown tumor mimicking maxillary sinus mucocele as the first manifestation of primary hyperparathyroidism. Auris, Nasus, Larynx 2012; 39:418–421.

Ishii H, Taniguchi H, Shiozaki A, Kuriu Y, et al. Use of Multidetector-Row Computed Tomography to Evaluate Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas: Influence on Surgical Decision-Making. Hepato-Gastroenterol 2012; 59:884–888.

Kelly CP. Large intestine. Curr Opin Gastroenterol 2012; 28:36–38. View Full Text | PubMed | CrossRef

Lee HS, Kim J, Lee HJ, Koh YW, et al. Transoral robotic surgery for neurogenic tumors of the prestyloid parapharyngeal space. Auris, Nasus, Larynx 2012; 39:434–437.

Okuno K, Horiuchi T, Ishibashi T, Shigeoka H, et al. Prognostic Factors in Gastrointestinal Perforation. Hepato-Gastroenterol 2011; 58:1598–1602.

Wilschut JA, Steyerberg EW, van Leerdam ME, Lansdorp-Vogelaar I, et al. How Much Colonoscopy Screening Should Be Recommended to Individuals With Various Degrees of Family History of Colorectal Cancer? Cancer 2011; 117:4166–4174.

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