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Functional lumen imaging probe: The FLIP side of esophageal disease

Carlson, Dustin A.

Current Opinion in Gastroenterology: July 2016 - Volume 32 - Issue 4 - p 310–318
doi: 10.1097/MOG.0000000000000272
ESOPHAGUS: Edited by Stuart J. Spechler

Purpose of review: The aim of this review is to summarize use of the functional lumen imaging probe (FLIP) for the evaluation and management of esophageal diseases.

Recent findings: The FLIP utilizes high-resolution impedance planimetry to evaluate the functional geometry and cross-sectional area/pressure relationship (i.e. distensibility) of the esophageal sphincters and body. Recent studies have reported the potential utility of FLIP to evaluate esophageal diseases, such as achalasia, gastroesophageal reflux disease, and eosinophilic esophagitis.

Summary: Esophageal distensibility measures provided by the FLIP will add to our understanding of the contribution of esophageal mechanical properties to esophageal symptoms and function. Application of the FLIP in clinical practice complements the diagnostic evaluation of esophageal function and may also be a valuable tool to help direct and target clinical management of esophageal diseases.

Department of Medicine, Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

Correspondence to Dustin A. Carlson, MD, MS, Department of Medicine, Division of Gastroenterology and Hepatology, Northwestern University Feinberg School of Medicine, 676 St Clair St, Suite 1400, Chicago, IL 60611-2951, USA. Fax: +1 312 695 3999; e-mail: dustin-carlson@northwestern.edu

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