Purpose of review: To provide a summary of the most recent research pertaining to the endocrine and metabolic complications observed in childhood cancer survivors.
Recent findings: Data on prevalence and risk associations are increasingly available from large cohorts of childhood cancer survivors. New directions in research include novel risk-prediction strategies and the study of genetic predisposition.
Summary: Endocrine complications are observed in more than 50% of adult childhood cancer survivors. Some continue to develop decades following cancer treatment exposures. The present review provides a summary of the most recent outcomes research pertaining to growth, thyroid, gonadal–reproductive, bone and body composition with emphasis on new directions and challenges in each area.