Purpose of review
To provide a summary of the most recent research pertaining to the endocrine and metabolic complications observed in childhood cancer survivors.
Data on prevalence and risk associations are increasingly available from large cohorts of childhood cancer survivors. New directions in research include novel risk-prediction strategies and the study of genetic predisposition.
Endocrine complications are observed in more than 50% of adult childhood cancer survivors. Some continue to develop decades following cancer treatment exposures. The present review provides a summary of the most recent outcomes research pertaining to growth, thyroid, gonadal–reproductive, bone and body composition with emphasis on new directions and challenges in each area.