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What the new obesity guidelines will tell us

Ryan, Donna H.a; Jensen, Michael D.b

Current Opinion in Endocrinology, Diabetes & Obesity:
doi: 10.1097/
OBESITY AND NUTRITION: Edited by Caroline M. Apovian and Jeffrey I. Mechanick

Purpose of review: The purpose of the review is to update the reader on the long anticipated Obesity 2, the second iteration of ‘Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults: the Evidence Report’.

Recent findings: Obesity 2 maintains a focus on primary care practitioners and their patients in an effort to reduce cardiovascular risk. Just as Obesity 1 limited the literature review to the years 1980–1997, Obesity 2 limits the literature under consideration from 1999 to 2011. However, because of the painstaking methodology employed, the scope of the Obesity 2 is of necessity more limited with five critical questions. These deal with risks of overweight and obesity, benefits of weight loss and evaluate three treatment areas – diet, behavioral therapies and surgical therapies. The critical questions inform recommendations in these same areas.

Summary: Although not comprehensive in scope, the guidance offered in Obesity 2 is backed by stringent approaches to limit bias and assuring rigor, thus producing recommendations one can trust in the areas covered.

Author Information

aPennington Biomedical Research Center, New Orleans, Los Angeles

bMayo Clinic, Rochester, Minnesota, USA

Correspondence to Donna H. Ryan, MD, FACP, Professor Emeritus, Pennington Biomedical Research Center, 625 St. Charles Avenue #10B, New Orleans, LA 70130, USA. Tel: +1 225 229 3909; e-mail:

© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins