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Current Opinion in Endocrinology, Diabetes & Obesity:
doi: 10.1097/
OBESITY AND NUTRITION: Edited by Caroline M. Apovian and Jeffrey I. Mechanick

Duodenal–jejunal bypass liners: outcomes in glycaemic control and weight loss

Neff, Karl J.a; Miras, Alex D.b; le Roux, Carela,b

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Purpose of review: Duodenal–jejunal bypass liners (DJBLs) are a novel therapy with potential treating a range of metabolic diseases. This review discusses the weight loss and glycaemic improvements observed following the use of the DJBL.

Recent findings: We summarize the evidence for the clinical application of DJBL to date. Within this, we outline the evidence available on the mechanisms of the observed effects.

Summary: Based on the most recent trials, we cannot fully mimic the clinical or physiological effects of bariatric surgery with this device, but we are getting closer.

© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins


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