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Current Opinion in Endocrinology, Diabetes & Obesity:
doi: 10.1097/01.med.0000433057.84323.2e
OBESITY AND NUTRITION: Edited by Caroline M. Apovian and Jeffrey I. Mechanick

Duodenal–jejunal bypass liners: outcomes in glycaemic control and weight loss

Neff, Karl J.a; Miras, Alex D.b; le Roux, Carela,b

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Abstract

Purpose of review

Duodenal–jejunal bypass liners (DJBLs) are a novel therapy with potential treating a range of metabolic diseases. This review discusses the weight loss and glycaemic improvements observed following the use of the DJBL.

Recent findings

We summarize the evidence for the clinical application of DJBL to date. Within this, we outline the evidence available on the mechanisms of the observed effects.

Summary

Based on the most recent trials, we cannot fully mimic the clinical or physiological effects of bariatric surgery with this device, but we are getting closer.

© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

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