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The worldwide diabetes epidemic

Lam, David W.; LeRoith, Derek

Current Opinion in Endocrinology, Diabetes & Obesity: April 2012 - Volume 19 - Issue 2 - p 93–96
doi: 10.1097/MED.0b013e328350583a
DIABETES AND THE ENDOCRINE PANCREAS I: Edited by David Harlan

Purpose of review: An overview of the global epidemic of diabetes and its impact on the understanding of the disease.

Recent findings: Once thought of as a disease of the West, the prevalence of diabetes mellitus is increasing at alarming rates in many other areas of the world. In recent years, significant attention has been placed on the growing Asian diabetes epidemic. As a result, the medical community has come to understand that previously defined risk factors, particularly BMI, may not be applicable to the global community. The heterogeneity of the disease has been demonstrated both through anthropometric and genetic studies. Despite this heterogeneity, some treatments, particularly lifestyle interventions, have been found to have an ethnic nonspecific positive impact on the disease.

Summary: Diabetes promises to become an even larger public health issue with significant social and economic burden with clinical practice and public health policy implications. Further population studies and identification of ethnic specific risk factors will guide research to develop a better understanding of the disease.

Division of Endocrinology, Diabetes and Bone Diseases, Mount Sinai School of Medicine, New York, New York, USA

Correspondence to Derek LeRoith, MD, PhD, Mount Sinai School of Medicine, One Gustave Levy Place Box 1055, Atran Building 4th Floor, New York, NY 10029–6574, USA. Tel: +1 212 241 6306; fax: +1 212 241 4159; e-mail: derek.leroith@mssm.edu

© 2012 Wolters Kluwer Health | Lippincott Williams & Wilkins