Contemporary management of fibromuscular dysplasiaOlin, Jeffrey W; Pierce, MatthewCurrent Opinion in Cardiology: November 2008 - Volume 23 - Issue 6 - p 527–536 doi: 10.1097/HCO.0b013e328313119a Diseases of the aorta, pulmonary and peripheral vessels: Edited by Alan C. Braverman Abstract Author Information Purpose of review Fibromuscular dysplasia is an underdiagnosed and misunderstood disease. The purpose of this review is to inform healthcare providers and the public about a condition that may be more common than previously thought. Recent findings There has been little new information published about fibromuscular dysplasia in the past 30 years. The International Registry that is now underway will remedy that situation and provide a large number of patients to study with this condition. Summary Fibromuscular dysplasia is a noninflammatory, nonatherosclerotic disease that has been reported in almost every arterial bed and primarily affects women aged 15–50 years. It most commonly presents in the renal and extracranial cerebrovascular arteries, either manifesting as hypertension, transient ischemic attack or stroke, respectively. Some patients may be asymptomatic and fibromuscular dysplasia could only be discovered by imaging for some other reason or by the detection of an asymptomatic bruit. Dissection or aneurysm may also occur in patients with fibromuscular dysplasia. The true prevalence is unknown, partially because of the fact that it is underdiagnosed in many patients. Treatment consists of antiplatelet therapy for asymptomatic individuals and percutaneous balloon angioplasty for patients with indications for intervention. Patients with macroaneurysms should be treated with either a covered stent or surgery. Mount Sinai School of Medicine, New York, New York, USA Correspondence to Jeffrey W. Olin, DO, Professor of Medicine, Director, Vascular Medicine, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA Tel: +1 212 241 9454; fax: +1 212 242 5107; e-mail: firstname.lastname@example.org © 2008 Lippincott Williams & Wilkins, Inc.