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Current Opinion in Cardiology:
Ischemic heart disease

Optimal goals for statin use in patients with coronary artery disease

Ray, Kausik K; Cannon, Christopher P

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Abstract

Purpose of review: Coronary artery disease is the largest cause of premature death in the Western world. Lipid-lowering therapy with statins has revolutionized the management of this condition over the past decade.

Recent developments: Successive clinical trials have lowered the treatment bar for statin therapy in patients with coronary artery disease. In addition to traditional markers of efficacy such as low-density lipoprotein cholesterol, emerging targets such as C-reactive protein are becoming recognized as important therapeutic goals.

Summary: This review focuses on the important contributions to the literature during the past year and provides an expert opinion of the therapeutic goals for statin therapy.

© 2005 Lippincott Williams & Wilkins, Inc.

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