Pediatric traumatic brain injury (TBI) is associated with significant morbidity and mortality. The purpose of this review is to discuss emerging concepts and to provide an update on the clinical evaluation, management, and predictors of outcome after pediatric TBI.
We review the epidemiology, patterns of injury, and pathophysiology of pediatric TBI and focus on selective ‘hot topics’ such as biomarkers, glucose control, and the potential benefits of hypothermia after pediatric TBI.
As TBI is the leading cause of death in children, research in this area is needed to advance our knowledge of the sequelae after and improve outcomes of children with TBI.
aDepartment of Anesthesiology, Harborview Injury Prevention and Research Center, USA
bDepartment of Anesthesiology, Pediatrics and Neurological Surgery, University of Washington, Seattle, Washington, USA
Correspondence to Monica S. Vavilala, MD, Associate Professor, Department of Anesthesiology, Pediatrics and Neurological Surgery (Adj), Harborview Injury Prevention and Research Center, Box #359724, 325 Ninth Avenue, Seattle, WA 98104, USA Tel: +1 206 731 3210; fax: +1 206 731 8009; e-mail: firstname.lastname@example.org