Skip Navigation LinksHome > August 2008 - Volume 21 - Issue 4 > Recent advancements in the treatment of lumbar radicular pai...
Current Opinion in Anaesthesiology:
doi: 10.1097/ACO.0b013e328303bfc9
Drugs in anesthesia: Edited by Alan D. Kaye

Recent advancements in the treatment of lumbar radicular pain

Burnett, Chris; Day, Miles

Collapse Box

Abstract

Purpose of review: Lumbar radicular pain is a common and often difficult condition to treat. Current literature supports the theory that radicular pain is at least in part due to an inflammatory process involving cytokines, including tumor necrosis factor alpha and interleukins. This review summarizes some of the most recent research concerning the use of tumor necrosis factor alpha antagonists and interleukin receptor antagonists in the treatment of lumbar radicular pain.

Recent findings: Recent studies have shown promising results in the treatment of both acute and chronic lumbar radicular pain with tumor necrosis factor alpha antagonists such as etanercept and infliximab, as well as with interleukin receptor antagonists.

Summary: Treatment for lumbar radicular pain has long included epidural steroids to inhibit the inflammatory component of radicular pain. Recent studies have more precisely identified the cytokines responsible for this inflammatory process and indicate that inhibition of these cytokines may offer more specific and effective treatment for lumbar radicular pain.

© 2008 Lippincott Williams & Wilkins, Inc.

Login

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.