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Current Opinion in Allergy & Clinical Immunology:
doi: 10.1097/ACI.0b013e32835cb509
CURRENT WORLD LITERATURE: Bibliography

Current World Literature

Free Access

This bibliography is compiled by clinicians from the relevant journals scanned by this publication. It is based on the literature regularly pulled into our database from OvidSP (articles are generally added to the database about two and a half months after publication). In addition, the bibliography contains every paper annotated by reviewers; these references were obtained from a variety of bibliographic databases and published between the beginning of the review period and the time of going to press. The bibliography has been grouped into topics that relate to the reviews in this issue.

▪ Papers considered by the reviewers to be of special interest

▪▪ Papers considered by the reviewers to be of outstanding interest

The number in square brackets following a selected paper, e.g. [7], refers to its number in the annotated references of the corresponding review.

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Rhinitis, sinusitis and upper airway disease
Mucosal remodeling and reversibility in chronic rhinosinusitis

Review: (pp. 4–12)

▪. Bassiouni A, Naidoo Y, Wormald P-J. When FESS fails: the inflammatory load hypothesis in refractory chronic rhinosinusitis. Laryngoscope 2012; 122:460–466. [84]

Bassiouni A, Naidoo Y, Wormald PJ. Does mucosal remodeling in chronic rhinosinusitis result in irreversible mucosal disease? Laryngoscope 2012; 122:225–229.

Bassiouni A, Naidoo Y, Wormald PJ. When FESS fails: The inflammatory load hypothesis in refractory chronic rhinosinusitis. Laryngoscope 2012; 122:460–466. PubMed | CrossRef

Bystrom J, Patel SY, Amin K, Bishop-Bailey D. Dissecting the role of eosinophil cationic protein in upper airway disease. Curr Opin Allergy Clin Immunol 2012; 12:18–23. View Full Text | PubMed | CrossRef

de Bot CMA, Moed H, Berger MY, Roder E, et al. Sublingual immunotherapy in children with allergic rhinitis: quality of systematic reviews. Pediatr Allergy Immunol 2011; 22:548–558. View Full Text | PubMed | CrossRef

de Bot CMA, Moed H, Berger MY, Roder E, et al. Sublingual immunotherapy not effective in house dust mite-allergic children in primary care. Pediatr Allergy Immunol 2012; 23:151–159. View Full Text | PubMed

Hirano M, Ogita-Nakanishi H, Miyachi W, Hannya N, et al. Essential role of macrophages in the initiation of allergic rhinitis in mice sensitized intranasally once with cedar pollen: regulation of class switching of immunoglobulin in B cells by controlling interleukin-4 production in T cells of submandibular lymph nodes. Microbiol Immunol 2012; 56:392–405. View Full Text | PubMed | CrossRef

▪. Mendelsohn D, Jeremic G, Wright ED, Rotenberg BW. Revision rates after endoscopic sinus surgery: a recurrence analysis. Ann Otol Rhinol Laryngol 2011; 120:162–166. [38]

▪. Mudd PA, Katial RK, Alam R, et al. Variations in expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in nasal mucosa of aspirin-sensitive versus aspirin-tolerant patients with nasal polyposis. Ann Allergy Asthma Immunol 2011; 107:353–359. [41]

▪. Nakayama T, Yoshikawa M, Asaka D, et al. Mucosal eosinophilia and recurrence of nasal polyps: new classification of chronic rhinosinusitis. Rhinology 2011; 49:392–396. [30]

Sautter NB, De laney KL, Hausman FA, Trune DR. Tissue remodeling gene expression in a murine model of chronic rhinosinusitis. Laryngoscope 2012; 122:711–717. PubMed | CrossRef

Shah RK, Lander L, Berry JG, Nussenbaum B, et al. Tracheotomy outcomes and complications: A national perspective. Laryngoscope 2012; 122:25–29. PubMed | CrossRef

▪. Van Bruaene N, Bachert C. Tissue remodeling in chronic rhinosinusitis. Curr Opin Allergy Clin Immunol 2011; 11:8–11. [51]

van Drunen CM, Mjosberg JM, Segboer CL, Cornet ME, et al. Role of Innate Immunity in the Pathogenesis of Chronic Rhinosinusitis: Progress and New Avenues. Curr Allergy Asthma Rep 2012; 12:120–126. PubMed | CrossRef

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Role of interleukin-32 in chronic rhinosinusitis

Review: (pp. 13–18)

▪. Bai X, Ovrutsky AR, Kartalija M, et al. IL-32 expression in the airway epithelial cells of patients with Mycobacterium avium complex lung disease. Int Immunol 2011; 23:679–691. [13]

Ballardini N, Kull I, Lind T, Hallner E, et al. Development and comorbidity of eczema, asthma and rhinitis to age 12-data from the BAMSE birth cohort. Allergy 2012; 67:537–544. View Full Text | PubMed | CrossRef

Bousquet J, Heinzerling L, Bachert C, Papadopoulos NG, et al. Practical guide to skin prick tests in allergy to aeroallergens. Allergy 2012; 67:18–24. View Full Text | PubMed | CrossRef

▪. Heinhuis B, Koenders MI, van Riel PL, et al. Tumour necrosis factor alpha-driven IL-32 expression in rheumatoid arthritis synovial tissue amplifies an inflammatory cascade. Ann Rheum Dis 2011; 70:660–667. [23]

Keswani A, Chustz RT, Suh L, Carter R, et al. Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps. Allergy 2012; 67:25–32. View Full Text | PubMed | CrossRef

▪▪. Keswani A, Chustz RT, Suh L, et al. Differential expression of interleukin-32 in chronic rhinosinusitis with and without nasal polyps. Allergy 2012; 67:25–32. [27]

▪. Meyer N, Christoph J, Makrinioti H, et al. Inhibition of angiogenesis by IL-32: possible role in asthma. J Allergy Clin Immunol 2012; 129:964–973. e967. [26]

Sejima T, Holtappels G, Kikuchi H, Imayoshi S, et al. Cytokine Profiles in Japanese Patients with Chronic Rhinosinusitis. Allergol Int 2012; 61:115–122. PubMed | CrossRef

Seshadri S, Lin DC, Rosati M, Carter RG, et al. Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy 2012; 67:920–928. View Full Text | PubMed | CrossRef

▪▪. Soyka MB, Treis A, Eiwegger T, et al. Regulation and expression of IL-32 in chronic rhinosinusitis. Allergy 2012; 67:790–798. [41]

Soyka MB, Treis A, Eiwegger T, Menz G, et al. Regulation and expression of IL-32 in chronic rhinosinusitis. Allergy 2012; 67:790–798. View Full Text | PubMed | CrossRef

▪. Zepp JA, Nold-Petry CA, Dinarello CA, Nold MF. Protection from RNA and DNA viruses by IL-32. J Immunol 2011; 186:4110–4118. [21]

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Omalizumab and hypersensitivity reactions

Review: (pp. 19–24)

Berdel D, Sennekamp J, von Berg A. Are the terms and definitions ‘‘allergic march'' and ‘‘allergic career’' appopriate? Allergologie 2012; 35:323–326.

▪. Cox L, Lieberman P, Wallace D, et al. American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma & Immunology Omalizumab-Associated Anaphylaxis Joint Task Force follow-up report. J Allergy Clin Immunol 2011; 128:210–212. [45]

▪▪. Cox L, Nelson H, Lockey R, et al. Allergen immunotherapy: a practice parameter third update. J Allergy Clin Immunol 127(1 Suppl)2011:S1–S55. [31]

Fischer AJ, Lennemann NJ, Krishnamurthy S, Pocza P, et al. Enhancement of Respiratory Mucosal Antiviral Defenses by the Oxidation of Iodide. Am J Respir Cell Mol Biol 2011; 45:874–881. PubMed | CrossRef

Ishii T, Hagiwara K, Kamio K, Ikeda S, et al. Involvement of surfactant protein D in emphysema revealed by genetic association study. Eur J Hum Genet 2012; 20:230–235. PubMed | CrossRef

▪. Nadeau KC, Schneider LC, Hoyte L, et al. Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy. J Allergy Clin Immunol 2011; 127:1622–1624. [41]

Nurmatov U, van Schayck CP, Hurwitz B, Sheikh A. House dust mite avoidance measures for perennial allergic rhinitis: an updated Cochrane systematic review. Allergy 2012; 67:158–165. View Full Text | PubMed | CrossRef

▪▪. Simons FER, Ardusso LRF, Bilò MB, et al. 2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis. Curr Opin Allergy Clin Immunol 2012; 12:389–399. [04]

Vichyanond P. Omalizumab in allergic diseases, a recent review. Asian Pac J Allergy Immunol 2011; 29:209–219. PubMed

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Clara cell 10-kD protein in inflammatory upper airway diseases

Review: (pp. 25–30)

Calderon MA, Larenas D, Kleine-Tebbe J, Jacobsen L, et al. European Academy of Allergy and Clinical Immunology task force report on 'dose-response relationship in allergen-specific immunotherapy'. Allergy 2011; 66:1345–1359. View Full Text | PubMed | CrossRef

Calderon MA, Simons FER, Malling HJ, Lockey RF, et al. Sublingual allergen immunotherapy: mode of action and its relationship with the safety profile. Allergy 2012; 67:302–311. View Full Text | PubMed | CrossRef

▪▪. Cui YH, Wang YY, Liu Z. Transdifferentiation of Clara cell 10-kDa protein secreting cells in experimental allergic rhinitis. Am J Rhinol Allergy 2011; 25:145–151. [12]

▪. Irander K, Palm JP, Borres MP, Ghafouri B. Clara cell protein in nasal lavage fluid and nasal nitric oxide: biomarkers with anti-inflammatory properties in allergic rhinitis. Clin Mol Allergy 2012; 10:4. [16]

Jarvis D, Newson R, Lotvall J, Hastan D, et al. Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe. Allergy 2012; 67:91–98. View Full Text | PubMed | CrossRef

Jeanson L, Kelly M, Coste A, Guerrera IC, et al. Oxidative stress induces unfolding protein response and inflammation in nasal polyposis. Allergy 2012; 67:403–412. View Full Text | PubMed | CrossRef

▪▪. Liu Y, Lu X, Yu HJ, et al. The expression of osteopontin and its association with Clara cell 10 kDa protein in allergic rhinitis. Clin Exp Allergy 2010; 40:1632–1641. [17]

▪. Liu Z, Lu X, Zhang XH, et al. Clara cell 10-kDa protein expression in chronic rhinosinusitis and its cytokine-driven regulation in sinonasal mucosa. Allergy 2009; 64:149–157. [20]

▪. Long XB, Hu S, Wang N, et al. Clara cell 10-kDa protein gene transfection inhibits NF-kappaB activity in airway epithelial cells. PLOS ONE 2012; 7:e35960. [26]

▪▪. Wang H, Long XB, Cao PP, et al. Clara cell 10-kD protein suppresses chitinase 3-like 1 expression associated with eosinophilic chronic rhinosinusitis. Am J Respir Crit Care Med 2010; 181:908–916. [21]

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Chronic rhinosinusitis: observation or treatment

Review: (pp. 31–36)

Akdis C, Papadopoulos N, Cardona V. Fighting allergies beyond symptoms: The European Declaration on Immunotherapy. Eur J Immunol 2011; 41:2802–2804. PubMed | CrossRef

Asnaashari AMH, Rezaei S, Babaeian M, Taiarani M, et al. The effect of asthma on phonation: A controlled study of 34 patients. ENT-Ear Nose Throat J 2012; 91:168–171.

Ciebiada M, Cichocki P, Kasztalska K, Majewski S, et al. Orally exhaled nitric oxide in patients with seasonal allergic rhinitis during natural pollen season. Am J Rhinol Allergy 2012; 26:E32–E36. PubMed

Cingi C, Songu M, Ural A, Annesi-Maesano I, et al. The Score For Allergic Rhinitis study in Turkey. Am J Rhinol Allergy 2011; 25:333–337. PubMed

▪▪. Ferguson BJ, Narita M, Yu VL, et al. Prospective observational study of chronic rhinosinusitis: environmental triggers and antibiotic implications. Clin Infect Dis 2012; 54:62–68. [07]

Fischer AJ, Lennemann NJ, Krishnamurthy S, Pocza P, et al. Enhancement of Respiratory Mucosal Antiviral Defenses by the Oxidation of Iodide. Am J Respir Cell Mol Biol 2011; 45:874–881. PubMed | CrossRef

▪▪. Fokkens WJ, Lund VJ, Mullol J, et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists. Rhinology 2012; 50:1–12. [05]

▪. Gevaert P, Van Bruaene N, Cattaert T, et al. Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis. J Allergy Clin Immunol 2011; 128:989–995. e1–e8. [20]

Hamilos DL. Chronic rhinosinusitis: Epidemiology and medical management. J Allergy Clin Immunol 2011; 128:693–709. View Full Text | PubMed | CrossRef

▪▪. Jarvis D, Newson R, Lotvall J, et al. Asthma in adults and its association with chronic rhinosinusitis: the GA2LEN survey in Europe. Allergy 2012; 67:91–98. [23]

Lee S, Kundaria S, Ferguson BJ. Practical clinical management strategies for the allergic patient with chronic rhinosinusitis. Curr Opin Otolaryngol Head Neck Surg 2012; 20:179–187. View Full Text | PubMed | CrossRef

▪. Videler WJ, Badia L, Harvey RJ, et al. Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial. Allergy 2011; 66:1457–1468. [06]

▪. Woodbury K, Ferguson BJ. Recalcitrant chronic rhinosinusitis: investigation and management. Curr Opin Otolaryngol Head Neck Surg 2011; 19:1–5. [13]

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Indoleamine 2,3-dioxygenase expression is associated with chronic rhinosinusitis: review of the evidence

Review: (pp. 37–44)

Antonicelli L, Braschi MC, Bilo MB, Angino A, et al. Congruence between international guidelines and mite specific immunotherapy prescribing practices. Respir Med 2011; 105:1441–1448. PubMed | CrossRef

▪. Fallarino F, Grohmann U. Indoleamine 2,3-dioxygenase: from catalyst to signaling function. 2012; 42:1932–1937. [29]

Honkanen T, Luukkainen A, Lehtonen M, Paavonen T, et al. Indoleamine 2,3-dioxygenase expression is associated with chronic rhinosinusitis with nasal polyps and antrochoanal polyps. Rhinology 2011; 49:356–363. PubMed

▪. Loughman JA, Hunstad DA. Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection. J Infect Dis 2012; 205:1830–1839. [36]

▪. Munn DH. Blocking IDO activity to enhance antitumor immunity. Front Biosci (Elite Ed) 2012; 4:734–745. [66]

Solly WR, O'Connell RJ, Lee HJ, Sterman DH, et al. Diagnosis of Idiopathic Tracheal Stenosis and Treatment With Papillotome Electrocautery and Balloon Bronchoplasty. Respir Care 2011; 56:1617–1620. PubMed | CrossRef

▪▪. von Bubnoff D, Bieber T. The indoleamine 2,3-dioxygenase (IDO) pathway controls allergy. Allergy 2012; 67:718–725. [64]

von Bubnoff D, Bieber T. The indoleamine 2,3-dioxygenase (IDO) pathway controls allergy. Allergy 2012; 67:718–725.

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Rhinosinusitis and asthma-microbiome and new perspectives

Review: (pp. 45–49)

Bakaletz LO. Bacterial biofilms in the upper airway - evidence for role in pathology and implications for treatment of otitis media. Paediatr Respir Rev 2012; 13:154–159. PubMed | CrossRef

Bezerra TFP, Padua FGD, Gebrim E, Saldiva PHN, et al. Biofilms in Chronic Rhinosinusitis with Nasal Polyps. Otolaryngology - Head & Neck Surgery 2011; 144:612–616. View Full Text | PubMed | CrossRef

▪▪. Ege MJ, Mayer M, Normand AC, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011; 364:701–709. [24]

▪▪. Feazel LM, Robertson CE, Ramakrishnan VR, et al. Microbiome complexity and Staphylococcus aureus in chronic rhinosinusitis. Laryngoscope 2012; 122:467–472. [41]

Foreman A, Holtappels G, Psaltis AJ, Jervis-Bardy J, et al. Adaptive immune responses in Staphylococcus aureus biofilm-associated chronic rhinosinusitis. Allergy 2011; 66:1449–1456. View Full Text | PubMed | CrossRef

Han DM, Zhang L. Nasal cavity ventilation expansion techniques. Acta Oto-Laryngologica 2011; 131:1244–1248.

Jarvis D, Newson R, Lotvall J, Hastan D, et al. Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe. Allergy 2012; 67:91–98. View Full Text | PubMed | CrossRef

Jiang XJ, Guo XY, Yuan W, Li Q, et al. Long-term improvements in quality of life after functional endoscopic sinus surgery for adolescents with chronic rhinosinusitis. Acta Oto-Laryngologica 2012; 132:798–802.

Levy P, Pepin JL, Dematteis M. Pharyngeal Neuropathy in Obstructive Sleep Apnea: Where Are We Going? Am J Respir Crit Care Med 2012; 185:241–243.

Li H, Wang DH, Sun XC, Hu L, et al. Relationship between bacterial biofilm and clinical features of patients with chronic rhinosinusitis. Eur Arch Oto-Rhino-Laryn 2012; 269:155–163.

▪. Mai V, Young CM, Ukhanova M, et al. Fecal microbiota in premature infants prior to necrotizing enterocolitis. PLoS One 2011; 6:e20647. [20]

Murr AH, Goldberg AN, Pletcher SD, Dillehay K, et al. Some chronic rhinosinusitis patients have elevated populations of fungi in their sinuses. Laryngoscope 2012; 122:1438–1445. PubMed | CrossRef

▪▪. No Authors Given. The Human Microbiome Project Consortium. A framework for human microbiome research. Nature 2012; 486:215–221 [15]

Ono N, Kase K, Homma H, Kusunoki T, et al. Maxillary sinus infundibulum narrowing influences sinus abnormalities in spite of the presence or absence of allergy. Acta Oto-Laryngologica 2011; 131:1193–1197.

Proud D. Role of rhinovirus infections in asthma. Asian Pac J Allergy Immunol 2011; 29:201–208. PubMed

Ragab A, Essa N, El-Raghy N, Zahran W, et al. Evaluation of bacterial adherence and biofilm arrangements as new targets in treatment of chronic rhinosinusitis. Eur Arch Oto-Rhino-Laryn 2012; 269:537–544.

▪. Ravel J, Gajer P, Abdo Z, et al. Vaginal microbiome of reproductive-age women. Proc Natl Acad Sci USA 108(Suppl 1)2011:4680–4687. [19]

Rudmik L, Mace J, Ferguson BJ, Smith TL. Concurrent Septoplasty During Endoscopic Sinus Surgery for Chronic Rhinosinusitis: Does It Confound Outcomes Assessment? Laryngoscope 2011; 121:2679–2683.

Tatar EC, Tatar I, Ocal B, Korkmaz H, et al. Prevalence of Biofilms and Their Response to Medical Treatment in Chronic Rhinosinusitis without Polyps. Otolaryngology - Head & Neck Surgery 2012; 146:669–675. View Full Text | PubMed | CrossRef

▪. Van Crombruggen K, Zhang N, Gevaert P, et al. Pathogenesis of chronic rhinosinusitis: inflammation. J Allergy Clin Immunol 2011; 128:728–732. [37]

▪. Wu GD, Chen J, Hoffmann C, et al. Linking long-term dietary patterns with gut microbial enterotypes. Science 2011; 334:105–108. [17]

▪. Wylie KM, Mihindukulasuriya KA, Sodergren E, et al. Sequence analysis of the human virome in febrile and afebrile children. PLoS ONE 2012; 7:e27735. [16]

You HH, Zhuge P, Li D, Shao LX, et al. Factors affecting bacterial biofilm expression in chronic rhinosinusitis and the influences on prognosis. Am J Otolaryngol 2011; 32:583–590. PubMed | CrossRef

▪. Zella GC, Hait EJ, Glavan T, et al. Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. Inflamm Bowel Dis 2011; 17:1092–1100. [18]

Zhang Z, Kofonow JM, Finkelman BS, Doghramji L, et al. Clinical Factors Associated with Bacterial Biofilm Formation in Chronic Rhinosinusitis. Otolaryngology - Head & Neck Surgery 2011; 144:457–462.

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Mechanisms of allergy and adult asthma
Efficacy versus effectiveness trials: informing guidelines for asthma management

Review: (pp. 50–57)

Ali Z, Norsk P, Ulrik CS. Mechanisms and Management of Exercise-Induced Asthma in Elite Athletes. J Asthma 2012; 49:480–486.

▪. Apter AJ. Advances in adult asthma diagnosis and treatment and health outcomes, education, delivery, and quality in 2011: what goes around comes around. J Allergy Clin Immunol 2012; 129:69–75. [68]

Bacharier LB, Guilbert TW. Diagnosis and management of early asthma in preschool-aged children. J Allergy Clin Immunol 2012; 130:287–296. View Full Text | PubMed | CrossRef

▪. Barnes N, Price D, Colice G, et al. Asthma control with extrafine-particle hydrofluoroalkane-beclometasone vs. large-particle chlorofluorocarbon-beclometasone: a real-world observational study. Clin Exp Allergy 2011; 41:1521–1532. [33]

Bhulani N, Lalani S, Ahmed A, Jan Y, et al. Knowledge of asthma management by general practitioners in Karachi, Pakistan: comparison with international guidelines. Prim Care Respir J 2011; 20:448–451. PubMed

▪. Blais L, Kettani FZ, Beauchesne MF, et al. New measure of adherence adjusted for prescription patterns: the case of adults with asthma treated with inhaled corticosteroid monotherapy. Ann Pharmacother 2011; 45:335–341. [36]

▪. Blais L, Kettani FZ, Lemiere C, et al. Inhaled corticosteroids vs. leukotriene-receptor antagonists and asthma exacerbations in children. Respir Med 2011; 105:846–855. [43]

Blake K, Raissy H. Treatment of Pediatric Asthma with Proton Pump Inhibitors: Three Strikes, Game Over. Pediatr Allergy Immunol Pulmonol 2012; 25:119–122.

Boluyt N, Rottier BL, de Jongste JC, Riemsma R, et al. Assessment of Controversial Pediatric Asthma Management Options Using GRADE. Pediatrics 2012; 130:E658–E668. PubMed | CrossRef

▪▪. Brusselle G, Peche R, Van den Brande P, et al. Real-life effectiveness of extrafine beclometasone dipropionate/formoterol in adults with persistent asthma according to smoking status. Respir Med 2012; 106:811–819. [50]

▪. Busse WW, Morgan WJ, Taggart V, et al. Asthma outcomes workshop: overview. J Allergy Clin Immunol 2012; 129:S1–S8. [66]

Cayetano KS, Chan AL, Albertson TE, Yoneda KY. Bronchial Thermoplasty: A New Treatment Paradigm for Severe Persistent Asthma. Clin Rev Allergy Immunol 2012; 43:184–193. PubMed | CrossRef

▪. Chalkidou K, Tunis S, Whicher D, et al. The role for pragmatic randomized controlled trials (pRCTs) in comparative effectiveness research. Clin Trials 2012; 9:436–446. [14]

Chauhan BF, Ducharmc FM. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children - art. no. CD002314. Cochrane Database Syst Rev 2012; 2314.

▪. Chauhan BF, Ducharme FM. Antileukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev 2012; 5:CD002314. [39]

Christakis DA, Garrison MM, Lozano P, Meischke H, et al. Improving Parental Adherence with Asthma Treatment Guidelines: A Randomized Controlled Trial of an Interactive Website. Acad Pediatr 2012; 12:302–311.

Chuchalin AG. Bronchial asthma: new prospects in therapy. Ter Arkhiv 2012; 84:5–11.

▪▪. Cloutier MM, Schatz M, Castro M, et al. Asthma outcomes: composite scores of asthma control. J Allergy Clin Immunol 2012; 129:S24–S33. [67]

Czarnecka K, Chapman KR. The clinical impact of single inhaler therapy in asthma. Clin Exp Allergy 2012; 42:1006–1013. View Full Text | PubMed | CrossRef

▪. Dahlen SE, Dahlen B, Drazen JM. Asthma treatment guidelines meet the real world. N Engl J Med 2011; 364:1769–1770. [08]

▪. Ducharme FM, Lasserson TJ, Cates CJ. Addition to inhaled corticosteroids of long-acting beta2-agonists versus antileukotrienes for chronic asthma. Cochrane Database Syst Rev 2011:CD003137. [40]

▪. Ducharme FM, Noya FJ, Allen-Ramey FC, et al. Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors. Curr Med Res Opin 2012; 28:111–119. [42]

Dumitru C, Chan SMH, Turcanu V. Role of Leukotriene Receptor Antagonists in the Management of Pediatric Asthma An Update. Pediatr Drugs 2012; 14:317–330.

Emilsson M, Berndtsson I, Lotvall J, Millqvist E, et al. The influence of personality traits and beliefs about medicines on adherence to asthma treatment. Prim Care Respir J 2011; 20:141–147.

Guglani L, Havstad SL, Johnson CC, Ownby DR, et al. Effect of depressive symptoms on asthma intervention in urban teens. Ann Allergy Asthma Immunol 2012; 109:237. PubMed | CrossRef

Gustafson D, Wise M, Bhattacharya A, Pulvermacher A, et al. The Effects of Combining Web-Based eHealth With Telephone Nurse Case Management for Pediatric Asthma Control: A Randomized Controlled Trial. J Med Internet Res 2012; 14:41–59. PubMed

▪. Jarvinen TL, Sievanen H, Kannus P, et al. The true cost of pharmacological disease prevention. BMJ 2011; 342:d2175. [07]

▪. Kelly HW, Sternberg AL, Lescher R, et al. Effect of inhaled glucocorticoids in childhood on adult height. N Engl J Med 2012; 367:904–912. [57]

▪▪. Krishnan JA, Schatz M, Apter AJ. A call for action: comparative effectiveness research in asthma. J Allergy Clin Immunol 2011; 127:123–127. [04]

Lin JT, Chen P, Zhou X, Sun TY, et al. Budesonide/formoterol maintenance and reliever therapy in Chinese patients with asthma. Chin Med J 2012; 125:2994–3001. View Full Text | PubMed

Louis R, Schleich F, Barnes PJ. Corticosteroids Still at the Frontline in Asthma Treatment? Clin Chest Med 2012; 33:531.

Margellos-Anast H, Gutierrez MA, Whitman S. Improving Asthma Management among African-American Children via a Community Health Worker Model: Findings from a Chicago-Based Pilot Intervention. J Asthma 2012; 49:380–389. PubMed | CrossRef

McDonald VM, Higgins I, Simpson JL, Gibson PG. The importance of clinical management problems in older people with COPD and asthma: do patients and physicians agree? Prim Care Respir J 2011; 20:389–395.

▪. Melani AS, Bonavia M, Cilenti V, et al. Inhaler mishandling remains common in real life and is associated with reduced disease control. Respir Med 2011; 105:930–938. [52]

▪. Muller V, Galffy G, Eszes N, et al. Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations: a real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation. BMC Pulm Med 2011; 11:40. [51]

Murata A, Ling PM. Asthma Diagnosis and Management. Emerg Med Clin N Am 2012; 30:203.

▪. No Authors Given. Patient-Centered Outcomes Research Institute (PCORI). Draft methodology report. 23 July 2012. http://http://www.pcori.org/what-we-do/methodology/. [Accessed 30 October 2012] [64]

▪. Papi A, Haughney J, Virchow JC, et al. Inhaler devices for asthma: a call for action in a neglected field. Eur Respir J 2011; 37:982–985. [53]

Parry GD, Cooper CL, Moore JM, Yadegarfar G, et al. Cognitive behavioural intervention for adults with anxiety complications of asthma: Prospective randomised trial. Respir Med 2012; 106:802–810. PubMed | CrossRef

▪. Pinnock H, Ostrem A, Rodriguez MR, et al. Prioritising the respiratory research needs of primary care: the International Primary Care Respiratory Group (IPCRG) e-Delphi exercise. Prim Care Respir J 2012; 21:19–27. [10]

▪▪. Price D, Chisholm A, van der Molen T, et al. Reassessing the evidence hierarchy in asthma: evaluating comparative effectiveness. Curr Allergy Asthma Rep 2011; 11:526–538. [05]

▪. Price D, Chrystyn H, Kaplan A, et al. Effectiveness of same versus mixed asthma inhaler devices: a retrospective observational study in primary care. Allergy Asthma Immunol Res 2012; 4:184–191. [56]

▪▪. Price D, Musgrave SD, Shepstone L, et al. Leukotriene antagonists as first-line or add-on asthma-controller therapy. N Engl J Med 2011; 364:1695–1707. [41]

▪. Price D, Roche N, Christian Virchow J, et al. Device type and real-world effectiveness of asthma combination therapy: an observational study. Respir Med 2011; 105:1457–1466. [55]

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The β-2 agonist debate: is there still a problem?

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Epigenetic mechanisms and models in the origins of asthma

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The hygiene hypothesis in allergy and asthma: an update

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Estrogen effects in allergy and asthma

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Mechanisms of sustained signalling in asthma

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The role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation

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Genome-wide association studies in asthma: what they really told us about pathogenesis

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Phosphodiesterase inhibitors. Have they a future in asthma?

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Biomarkers for selecting treatment responsive subtypes I asthma

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Where are we with allergen immunotherapy for asthma: Is it really worth it?

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Immunohistoligic approaches to understanding asthma

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