Nonallergen-specific treatments for food allergyLieberman, Jay A.; Wang, JulieCurrent Opinion in Allergy and Clinical Immunology: June 2012 - Volume 12 - Issue 3 - p 293–301 doi: 10.1097/ACI.0b013e3283534cf8 FOOD ALLERGY: Edited by Alessandro Fiocchi and Julie Wang Abstract Author Information Purpose of review This review summarizes recent reports on nonallergen-specific therapies for food allergy. These therapies are especially appealing for food allergy because unlike allergen-specific immunotherapy, they would allow the treatment of multiple food allergies in a single patient with one therapy. Recent findings Chinese herbal therapy, anti-IgE, probiotics, engineered lactic acid bacteria, and helminth therapy are all examples of allergen nonspecific therapies that have been investigated in recent years. Although some have only been studied in animal models of food allergy, some are undergoing rigorous, human clinical trials. Summary Increasing amounts of research are examining the efficacy and safety of nonallergen-specific therapies for food allergy. There is hope that clinicians will have effective treatments either as an alternative or as an adjunct to immunotherapy. Division of Allergy and Immunology, Department of Pediatrics, Elliot and Roslyn Jaffe Food Allergy Institute, Mount Sinai School of Medicine, Manhattan, New York City, New York, USA Correspondence to Julie Wang, MD, Division of Allergy & Immunology, Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA. Tel: +1 212 241 5548; fax: +1 212 426 1902; e-mail: firstname.lastname@example.org Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.