Skip Navigation LinksHome > February 2012 - Volume 12 - Issue 1 > Vitamin D and chronic rhinitis
Current Opinion in Allergy & Clinical Immunology:
doi: 10.1097/ACI.0b013e32834eccdb
RHINITIS, SINUSITIS AND UPPER AIRWAY DISEASE: Edited by Ruby Pawankar and David P. Skoner

Vitamin D and chronic rhinitis

Abuzeid, Waleed M.; Akbar, Nadeem A.; Zacharek, Mark A.

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Abstract

Purpose of review: To discuss the role of vitamin D in chronic rhinitis and chronic rhinosinusitis (CRS).

Recent findings: Vitamin D has been shown to have an immunomodulatory effect with a significant impact on immune function. Specifically, vitamin D regulates the mechanisms which suppress the inflammatory response and direct the differentiation fate of immune cells. Vitamin D has been shown to play an important role in asthma, and the concept of the unified airway model allows the extrapolation of vitamin D as a critical player in chronic rhinitis and rhinosinusitis.

Summary: Recent findings on the function of vitamin D may explain aspects of the pathophysiology of chronic rhinitis and CRS, and may help direct future treatment of these diseases.

© 2012 Lippincott Williams & Wilkins, Inc.

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