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Cow's milk allergy as a global challenge

Sackesen, Cansin; Assa'ad, Amal; Baena-Cagnani, Carlos; Ebisawa, Motohiro; Fiocchi, Alessandro; Heine, Ralf G; Von Berg, Andrea; Kalayci, Omer

Current Opinion in Allergy and Clinical Immunology: June 2011 - Volume 11 - Issue 3 - p 243–248
doi: 10.1097/ACI.0b013e328346566f
Food allergy: Edited by Alessandro Fiocchi and Anna Nowak-Wegrzyn

Purpose of review Cow's milk is a leading cause of food allergy especially in infants and children. ‘Diagnosis and Rationale for Action against Cow's Milk Allergy’ published by the World Allergy Organization has underlined that there is not enough information concerning geographical trends in cow's milk allergy (CMA) in children or adults. Experts from Australia, Asia, North America, Latin America, the Middle East and Europe have gathered together in a 2-day meeting in order to present various regional approaches to CMA. This report is a summary of the information that was presented at this meeting.

Recent findings Even though there seems to be uniformity concerning the diagnosis and treatment of CMA, the diagnostic approach to CMA shows variations among different regions. Common concerns were inadequate applications of challenge tests for the diagnosis and inadequate supply of the cow's milk substitute formulas.

Summary CMA is a global challenge and collaboration of the national and international scientific communities is essential to produce and update practical guidelines for CMA.

aPediatric Allergy and Asthma Unit, School of Medicine, Hacettepe University, Ankara, Turkey

bDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

cDivision of Immunology and Respiratory Medicine, Department of Pediatric, Infantile Hospital Cordoba, Santa Rosa, Cordoba, Argentina

dDepartment of Allergy, Clinical Research Center for Allergy and Rheumatology, Sagamihara National Hospital, Kanagawa, Japan

ePaediatric Division, Department of Child and Maternal Medicine, University of Milan Medical School at the Melloni Hospital, Milan, Italy

fDepartment of Allergy & Immunology, Royal Children's Hospital, University of Melbourne, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia

gResearch Institute, Children's Department, Marien-Hospital, Wesel, Germany

*Cansin Sackesen and Alessandro Fiocchi contributed equally to the writing of this article.

Correspondence to Cansin Sackesen, MD, Pediatric Allergy and Asthma Unit, School of Medicine, Hacettepe University, Hacettepe, 06100 Ankara, Turkey Tel: +90 312 305 1700; e-mail:

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