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Current Opinion in Allergy & Clinical Immunology:
doi: 10.1097/ACI.0b013e3282ef69e3
Eye allergy

Future directions in therapeutic interventions for conjunctival inflammatory disorders

Pflugfelder, Stephen C; Stern, Michael E

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Abstract

Purpose of review: To review recent advances in pathogenesis and treatment of conjunctival inflammatory disorders.

Recent findings: The conjunctiva becomes inflamed in a number of conditions, including allergy, atopy, dry eye, mucus membrane pemphigoid, Stevens-Johnson syndrome and surgical manipulation. Basic and clinical studies have identified a number of inflammatory mediators as potential therapeutic targets in these conditions. Additionally, new therapeutic agents and enhanced delivery systems have been evaluated.

Summary: Increased understanding of the key mediators of conjunctival inflammation coupled with improved drug delivery methods are leading to more effective therapy for conjunctival inflammatory disorders.

Copyright © 2007 Wolters Kluwer Health, Inc. All rights reserved.

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