Skip Navigation LinksHome > March 2013 - Volume 20 - Issue 2 > Asthma and Infections: An Update on Asthma Exacerbations
Clinical Pulmonary Medicine:
doi: 10.1097/CPM.0b013e318285c4e0
Obstructive Airways Disease

Asthma and Infections: An Update on Asthma Exacerbations

Sykes, Annemarie MBBS, PhD

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Abstract

Asthma is common, affecting approximately 300 million people of all ages globally and the incidence is increasing in many countries. Although stable asthma is a problem, the majority of mortality morbidity and health care expenditure is associated with asthma exacerbations. The majority of asthma exacerbations are related to respiratory virus infections, particularly rhinovirus, and asthmatic airways may have a defective interferon response to rhinovirus infection. This review summarizes the current literature on the role of viruses, evidence for defective interferon induction in asthma, and suggests a potential role for bacteria in asthma exacerbations.

© 2013 Lippincott Williams & Wilkins, Inc.

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