The Clinical Journal of Pain

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The Clinical Journal of Pain:
May 2006 - Volume 22 - Issue 4 - pp 325-331
doi: 10.1097/01.ajp.0000208249.07949.d5
Original Articles

Musculoskeletal Pain and Menopausal Status

Dugan, Sheila A. MD; Powell, Lynda H. PhD; Kravitz, Howard M. DO, MPH; Everson Rose, Susan A. PhD, MPH; Karavolos, Kelly MA; Luborsky, Judith PhD

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Abstract

Objectives: The authors examined whether self-reported menopausal status is associated with musculoskeletal pain in a multiethnic population of community-dwelling middle-aged women after considering sociodemographics, medical factors, smoking, depression, and body mass index using a cross-sectional study design.

Methods: Participants were 2218 women from the Study of Women's Health Across the Nation assessed at the time of their third annual follow-up exam. Two dependent variables were derived from a factor analysis of survey questions about pain. These 2 outcomes were Aches and Pains, derived from 5 of 6 pain symptom questions and Consultation for Low Back Pain, derived from 1 question.

Results: Prevalence of aches and pains was high, with 1 in 6 women reporting daily symptoms. Compared with premenopausal women, those who were early perimenopausal (P=0.002), late perimenopausal (P=0.002), or postmenopausal (P<0.0001) reported significantly more aches and pains in age-adjusted analysis. With complete risk factor adjustment, postmenopausal women still reported significantly greater pain symptoms (P=0.03) than did premenopausal women. Menopausal status was marginally related to consulting a healthcare provider for back pain.

Discussion: This study demonstrates an association between pain and self-reported menopausal status, with postmenopausal women experiencing greater pain symptoms than premenopausal women.

© 2006 Lippincott Williams & Wilkins, Inc.

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