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Clinical Journal of Pain:
doi: 10.1097/AJP.0000000000000077
Original Article: PDF Only

Cognitive Mediators of Treatment Outcomes in Pediatric Functional Abdominal Pain.

Levy, Rona L. MSW, PhD, MPH; Langer, Shelby L. PhD; Romano, Joan M. PhD; Labus, Jennifer PhD; Walker, Lynn S. PhD; Murphy, Tasha B. PhD; Van Tilburg, Miranda PhD; Feld, Lauren D.; Christie, Dennis L. MD; Whitehead, William E. PhD

Published Ahead-of-Print
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Abstract

Objectives: Cognitive-behavioral interventions improve outcomes for many pediatric health conditions, but little is known about which mechanisms mediate these outcomes. The goal of this study was to identify whether changes in targeted process variables from baseline to one week post-treatment mediate improvement in outcomes in a randomized controlled trial of a brief cognitive-behavioral intervention for idiopathic childhood abdominal pain.

Methods: Two-hundred children with persistent functional abdominal pain and their parents were randomly assigned to one of two conditions: a 3-session social learning and cognitive-behavioral treatment (SLCBT) (N=100), or a 3-session educational intervention controlling for time and attention (N=100). Outcomes were assessed at 3, 6 and 12 month follow-ups. The intervention focused on altering parental responses to pain and on increasing adaptive cognitions and coping strategies related to pain in both parents and children.

Results: Multiple mediation analyses were applied to examine the extent to which the effects of the SLCBT condition on child GI symptom severity and pain as reported by children and their parents were mediated by changes in targeted cognitive process variables and parents' solicitous responses to their child's pain symptoms. Reductions in parents' perceived threat regarding their child's pain mediated reductions in both parent- and child-reported GI symptom severity and pain. Reductions in children's catastrophic cognitions mediated reductions in child-reported GI symptom severity but no other outcomes. Reductions in parental solicitousness did not mediate outcomes.

Discussion: Results suggest that reductions in reports of children's pain and GI symptoms following a social learning and cognitive-behavioral intervention were mediated at least in part by decreasing maladaptive parent and child cognitions.

(C) 2014 by Lippincott Williams & Wilkins

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