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Clinical Journal of Pain:
doi: 10.1097/AJP.0b013e318292189e
Online Articles: Case Reports

Favorable Outcome of an Acute Complex Regional Pain Syndrome With Immunoglobulin Infusions

Medlin, Friedrich MD; Zekeridou, Anastasia MD; Renaud, Susanne MD; Kuntzer, Thierry MD

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Objective: To emphasize that complex regional pain syndrome (CRPS), a disabling disorder with the implication of aberrant inflammation, vasomotor dysfunction, and maladaptive neuroplasticity, might be treated with a high dose of intravenous immunoglobulin infusions (IVIG).

Methods: We describe a patient who presented with CRPS in the acute phase of the disease.

Results: The CRPS developed secondary to sciatic compression in a young patient and was treated within 10 days by high-dose IVIG (2 g/kg). It resolved completely within days after infusions.

Discussion: This observational study emphasizes that high-dose IVIG may be a treatment option in the acute phase of CRPS.

© 2013 by Lippincott Williams & Wilkins

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