Although health care recommendations should be agreed upon by a patient and her provider, patients cannot always follow these recommendations. Adherence remains low despite decades of research, highlighting the need for innovative approaches to tackle this problem. Interventions to improve adherence can capitalize on our reliance on technology. Digital technology interventions show promise in aiding patients attain and maintain their health care goals, including adherence to medication regimens and vaccination recommendations, receiving necessary treatment, attending appointments, and maintaining healthy behaviors. We present suggestions for clinicians who want to incorporate technologies to help their patients better engage in their health care.