Skip Navigation LinksHome > June 2013 - Volume 56 - Issue 2 > Pharmacology and Pharmacogenomics of Neurological Medication...
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e31828f241d
Neurologic Diseases in Pregnancy: An Overview

Pharmacology and Pharmacogenomics of Neurological Medications Used in Pregnancy

CAMPBELL, SARAH C. PhD; SPIGARELLI, MICHAEL G. MD, PhD

Collapse Box

Abstract

Pregnancy increases the pharmacological management challenge of numerous neurological diseases as a result of complex physiological changes. Understanding pregnancy-induced changes in pharmacokinetic and pharmacodynamic parameters can lead to better outcomes for both the mother and baby. Although the application of pharmacogenomics in maternal-fetal medicine is in its infancy, further research and developments will provide important new developments for managing the efficacy of drug treatments during pregnancy and improving maternal-fetal safety. Although a wide variety of neurological medications are used during pregnancy, this article will focus on the drugs with currently known pharmacogenomic implications.

© 2013, Lippincott Williams & Wilkins

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.