Skip Navigation LinksHome > December 2012 - Volume 55 - Issue 4 > Neonatal Herpes Simplex Virus Infection
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e31827146a7
Severe Infections in Gynecology

Neonatal Herpes Simplex Virus Infection

CHERPES, THOMAS L. MD; MATTHEWS, DEAN B. BS; MARYAK, SAMANTHA A. BS

Collapse Box

Abstract

Neonatal herpes, seen roughly in 1 of 3000 live births in the United States, is the most serious manifestation of herpes simplex virus (HSV) infection in the perinatal period. Although acyclovir therapy decreases infant mortality associated with perinatal HSV transmission, development of permanent neurological disabilities is not uncommon. Mother-to-neonate HSV transmission is most efficient when maternal genital tract HSV infection is acquired proximate to the time of delivery, signifying that neonatal herpes prevention strategies need to focus on decreasing the incidence of maternal infection during pregnancy and more precisely identifying infants most likely to benefit from prophylactic antiviral therapy.

© 2012 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.