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Group A Streptococcal Infections in Obstetrics and Gynecology

RIMAWI, BASSAM H. MD*; SOPER, DAVID E. MD*; ESCHENBACH, DAVID A. MD

Clinical Obstetrics & Gynecology: December 2012 - Volume 55 - Issue 4 - p 864–874
doi: 10.1097/GRF.0b013e31827362fc
Severe Infections in Gynecology

Group A streptococcal (GAS) infections continue to be an infrequent, but potentially lethal infections in women despite the victory over childbed fever in the 1800s. Invasive group A streptococcal infection still causes 40% of septic deaths among patients with postpartum endometritis, necrotizing fasciitis, and toxic shock syndrome. Many times symptoms and signs of this infection are nonspecific, but laboratory evaluation can suggest serious infection. The prudent combination of antibiotic and surgical therapy can be lifesaving.

*Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, South Carolina;

Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington

The authors declare that they have nothing to disclose.

Correspondence: David E. Soper, MD, Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC. E-mail: soperde@musc.edu

© 2012 Lippincott Williams & Wilkins, Inc.