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Obstetric and Neonatal Outcomes of Cancer Treated During Pregnancy

WALTON, JANELLE R. MD*; PRASAD, MONA R. DO, MPH

Clinical Obstetrics & Gynecology: December 2011 - Volume 54 - Issue 4 - p 567–573
doi: 10.1097/GRF.0b013e318236e781
Cancer In Pregnancy

Cancer diagnosed during pregnancy is a rare occurrence with an incidence of 0.1% of all pregnancies. However, its management can be challenging at times as one balances maternal benefit to fetal risk. Various treatment modalities are used in this context including surgical intervention, chemotherapy, and radiologic therapy. This review seeks to address the impact of pregnancy on disease as well as the effect of malignancy and its treatment on both mother and fetus. Attention is focused on the more common malignancies associated with pregnancy: cervix, breast, melanoma, and hematologic malignancies. In addition, special emphasis is placed on timing of delivery and how that affects neonatal outcomes.

*Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Northwestern University, Feinberg School of Medicine, Chicago, Illinois

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, The Ohio State University College of Medicine, Columbus, Ohio

The authors declare that they have nothing to disclose.

Correspondence: Mona R. Prasad, DO, MPH, The Ohio State University Medical Center, Division of Maternal Fetal Medicine, 395 W 12th Ave 5th floor, Columbus OH 43210. E-mail: mona.prasad@osumc.edu.

© 2011 Lippincott Williams & Wilkins, Inc.