You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Screening for Thyroid Disease During Pregnancy

MILLER, EMILY S. MD, MPH; GROBMAN, WILLIAM A. MD, MBA

Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e3182272ebf
Thyroid Disease in Pregnancy
Abstract

Overt thyroid disease is a well-established risk factor for adverse pregnancy and perinatal outcomes. Whether or not subclinical thyroid dysfunction carries these same risks has been a matter of controversy. There is inconsistent evidence on the association of subclinical thyroid dysfunction (ie, subclinical hypothyroidism or isolated hypothyroxinemia) with a woman's pregnancy outcome or the cognitive development of her offspring and there are no interventional trials that have shown that women with subclinical hypothyroidism who are treated have improved outcomes. Until such data are available, it is premature to recommend universal screening for thyroid disease in pregnancy or treatment of women who have subclinical thyroid dysfunction.

Author Information

Northwestern University, Chicago, Illinois

Disclosure: None.

Correspondence: Emily S. Miller, MD, MPH, Northwestern University, 250 E Superior, Suite 05-2177, Chicago, IL 60611. E-mail: emily-miller-1@md.northwestern.edu

© 2011 Lippincott Williams & Wilkins, Inc.