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Uterine Papillary Serous Carcinoma

MOORE, KATHLEEN N. MD*; NICKLES FADER, AMANDA MD

Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e318218c755
Endometrial Cancer
Abstract

Uterine papillary serous carcinoma (UPSC) is a histologic variant of endometrial cancer that accounts for only 10% of new cases of uterine cancer but is responsible for 40% of deaths from the disease. UPSC is an aggressive tumor with a predilection for early spread beyond the uterus. Treatment for UPSC typically entails surgery and in most women is followed by multimodality adjuvant therapy. In this review, we describe the epidemiology, natural history, treatment, and outcome of UPSC.

Author Information

*Department of Gynecologic Oncology, University of Oklahoma, Oklahoma City, Oklahoma

Greater Baltimore Medical Center, Baltimore, Maryland

Correspondence: Kathleen N. Moore, MD, Gynecologic Oncology, University of Oklahoma, 920 SL Young Boulevard, Oklahoma City, OK. e-mail: kathleen-moore@ouhsc.edu

© 2011 Lippincott Williams & Wilkins, Inc.