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Management of Endometrial Cancer in Young Women

SHAH, MONJRI M. MD; WRIGHT, JASON D. MD

Clinical Obstetrics and Gynecology: June 2011 - Volume 54 - Issue 2 - p 219–225
doi: 10.1097/GRF.0b013e318218607c
Endometrial Cancer

Endometrial cancer is the most common gynecologic cancer and its incidence is rising among premenopausal women. Hysterectomy and bilateral salpingo-oophorectomy, traditional treatment for endometrial cancer, causes loss of fertility and ovarian function, both of which can significantly negatively impact a young woman's physical and mental well-being. Recently, conservative management with progestational agents has been reported with success from both oncologic and reproductive perspectives. However, there are no randomized trials comparing conservative versus surgical therapy. Patients who are candidates for conservative therapy must be extensively counseled regarding the risks and must comply with close surveillance.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York

Correspondence: Jason D. Wright, MD, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, 161 Fort Washington Ave, 8th Floor, New York, NY. e-mail: jw2459@columbia.edu

© 2011 Lippincott Williams & Wilkins, Inc.