Skip Navigation LinksHome > June 2011 - Volume 54 - Issue 2 > Impact of Preterm PROM and its Complications on Long-term In...
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e318217ee18
Preterm Premature Rupture Of The Membranes

Impact of Preterm PROM and its Complications on Long-term Infant Outcomes

CLARK, ERIN A. S. MD; VARNER, MICHAEL MD

Collapse Box

Abstract

There is increasing evidence that preterm premature rupture of membranes (PPROM) is associated with increased risk for adverse neurodevelopmental outcomes through multiple mechanisms, including preterm birth and its antecedent etiologies. Intrauterine infection is a particularly important risk factor for adverse neurodevelopmental outcomes after PPROM. This review focuses on the long-term neurodevelopmental outcomes after PPROM, the possible etiologic mechanisms of neurological injury, and the effect of antenatal and perinatal interventions using available evidence.

© 2011 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.