Skip Navigation LinksHome > June 2011 - Volume 54 - Issue 2 > Antenatal Corticosteroids After Preterm Premature Rupture of...
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e318217d85b
Preterm Premature Rupture Of The Membranes

Antenatal Corticosteroids After Preterm Premature Rupture of Membranes

VIDAEFF, ALEX C. MD, MPH; RAMIN, SUSAN M. MD

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Abstract

Preterm premature rupture of membranes (PPROM) is an obstetrical complication associated with high neonatal morbidity and mortality. The current management of PPROM focuses on neonatal benefit and includes the ancillary use of corticosteroids for fetal maturation. The purpose of this work was to provide a comprehensive and unbiased review of the available literature on prenatal administration of corticosteroids in conditions of PPROM, and to address the rationale and the relevant supporting evidence for this practice. We conclude that the cumulative level I evidence indicates a definite beneficial effect of corticosteroids in conditions of PPROM.

© 2011 Lippincott Williams & Wilkins, Inc.

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