Uterine Artery Doppler in First-trimester Pregnancy ScreeningBAHADO-SINGH, RAY O. MD, MBA; JODICKE, CRISTIANO MDClinical Obstetrics & Gynecology: December 2010 - Volume 53 - Issue 4 - pp 879-887 doi: 10.1097/GRF.0b013e3181fbb65d New Horizons In Doppler Imaging In Obstetrics Abstract Author Information Uterine artery Doppler velocimetry has revolutionized the investigation of the developing placental vasculature. Abnormal placental vascular development is the basis of common obstetric disorders such as preeclampsia and intrauterine growth restriction. Uterine artery Doppler velocimetry by itself or in combination with other biochemical markers seems to be an effective first-trimester screening tool for preeclampsia and in particular early-onset preeclampsia. The diagnostic accuracy although statistically significant, is not as high for the prediction of intrauterine growth restriction unrelated to preeclampsia. In the future, first-trimester prophylaxis using antiplatelet agents in Doppler identified high-risk groups could suppress the development of these disorders. Department of Ob/Gyn, Detroit Michigan, Wayne State University, Michigan Correspondence: Ray O. Bahado-Singh, MD, MBA, Harper Hospital, OB/Ultrasound, 3980 John R, Box 160, Detroit, Michigan. E-mail: firstname.lastname@example.org © 2010 Lippincott Williams & Wilkins, Inc.