Skip Navigation LinksHome > December 2010 - Volume 53 - Issue 4 > Fertility Preservation in Women With Breast Cancer
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e3181f96e00
Fertility Preservation: New Developments

Fertility Preservation in Women With Breast Cancer

RODRIGUEZ-WALLBERG, KENNY A. MD, PhD* †; OKTAY, KUTLUK MD

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Abstract

Fertility preservation is an important issue for young women diagnosed with breast cancer. The most well-established options for fertility preservation in cancer patients, embryo and oocyte cryopreservation, have not been traditionally offered to breast cancer patients as estradiol rise during standard stimulation protocols may not be safe for those patients. Potentially safer stimulation protocols using tamoxifen and aromatase inhibitors induce lower levels of estradiol whereas similar results in terms of number of oocyte and embryo obtained to standard protocols. Cryopreservation of immature oocytes and ovarian cortical tissue, both still experimental methods, are also fertility preservation options for breast cancer patients.

© 2010 Lippincott Williams & Wilkins, Inc.

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