Skip Navigation LinksHome > September 2010 - Volume 53 - Issue 3 > Genetics of Stillbirth
Clinical Obstetrics & Gynecology:
doi: 10.1097/GRF.0b013e3181ee2793
Stillbirth

Genetics of Stillbirth

WAPNER, RONALD J. MD

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Abstract

Approximately 25% of stillbirths have been attributed to genetic etiologies. The most common cytogenetic abnormalities are similar to those seen in liveborns and include 45X, trisomy 21, trisomy 18, and trisomy 13. Cytogenetic abnormalities are more common when fetal structural anomalies are identified. Mendelian and metabolic causes of stillbirth are less well understood although single gene disorders can result in stillbirth. With new cytogenetic and molecular technologies additional genetic causes of stillbirth are likely to be described and will provide additional information for appropriate genetic counseling.

© 2010 Lippincott Williams & Wilkins, Inc.

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