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Invasive and Noninvasive Methods for the Diagnosis of Endometriosis

HSU, ALBERT L. MD; KHACHIKYAN, IZABELLA MD; STRATTON, PAMELA MD

Clinical Obstetrics & Gynecology: June 2010 - Volume 53 - Issue 2 - pp 413-419
doi: 10.1097/GRF.0b013e3181db7ce8
Endometriosis

Endometriosis has been associated with pain and infertility. The gold standard for the diagnosis of endometriosis has been visual inspection by laparoscopy, preferably with histologic confirmation. Because there is no good noninvasive test for endometriosis, there is often a significant delay in diagnosis of this disease. Imaging that confirms an endometriotic cyst or deep infiltrating endometriosis may help guide surgical therapeutic approaches. No serum marker has been found to diagnose endometriosis with adequate sensitivity and specificity. There has been a recent focus on the presence of nerve fibers in the eutopic endometrium of patients with endometriosis.

Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland

Funding for this work was provided exclusively by the Eunice Kennedy Shriver National Institute of Child Health and Human Development. No pharmaceutical or industry funding was accepted in the preparation of this manuscript.

Correspondence: Pamela Stratton, MD, Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Building 10, CRC, Room 1-3140, 10 Center Drive, MSC 1109, Bethesda, MD. E-mail: strattop@mail.nih.gov

© 2010 Lippincott Williams & Wilkins, Inc.